Folate and vitamin B12 status in schizophrenic patients

Journal of Research in Medical Sciences

Volumn 16, Issue SPEC. ISSUE, 2011, Pages 437-441

  Saedisomeolia, Ahmad ^a   Djalali, Mahmoud ^a   Moghadam, Ali Malekshahi ^b   Ramezankhani, Ozra ^a   Najmi, Laya ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Eating; Folic acid; Schizophrenia; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE COUNT; FEMALE; FOLIC ACID BLOOD LEVEL; FOLIC ACID DEFICIENCY; HUMAN; IRAN; ISOTOPE DILUTION ASSAY; MAJOR CLINICAL STUDY; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; SCHIZOPHRENIA; VITAMIN BLOOD LEVEL;

EID: 79955553886     PISSN: 17351995     EISSN: 17357136     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Stabler SP, Marcell PD, Podell ER, Allen RH, Savage DG, Lindenbaum J. Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry. J Clin Invest 1988; 81(2): 466-74.
2. Bottiglieri T. Folate, vitamin B12, and neuropsychiatric disorders. Nutr Rev 1996;54(12):382-90.
3. Levi RN, Waxman S. Schizophrenia, epilepsy, cancer, methionine, and folate metabolism. Pathogenesis of schizophrenia. Lancet 1975; 2(7923): 11-3.
4. Silver H. Vitamin B12 levels are low in hospitalized psychiatric patients. Isr J Psychiatry Relat Sci 2000; 37(1): 41-5.
5. Monji A, Yanagimoto K, Maekawa T, Sumida Y, Yamazaki K, Kojima K. Plasma folate and homocysteine levels may be related to interictal schizophrenia-like psychosis in patients with epilepsy. J Clin Psychopharmacol 2005; 25(1): 3-5.
6. th ed. Washington: American Psychiatric Association Inc.; 2000.
7. Zemlin AE, Essack Y, Rensburg M, Jephtha E, Abrahams N, Brinkmann T. Red blood cell folate stability study: stability of whole blood prior to haemolysate preparation and stability of the haemolysate at various temperatures. Med Technol SA 2009; 23(1): 14-6.
8. García-Miss Mdel R, Pérez-Mutul J, López-Canul B, Solís-Rodríguez F, Puga-Machado L, Oxté-Cabrera A, et al. Folate, homocysteine, interleukin-6, and tumor necrosis factor alfa levels, but not the methylenetetrahydrofolate reductase C677T polymorphism, are risk factors for schizophrenia. J Psychiatr Res 2010; 44(7): 441-6.
9. Reif A, Pfuhlmann B, Lesch KP. Homocysteinemia as well as methylenetetrahydrofolate reductase polymorphism are associated with affective psychoses. Prog Neuropsychopharmacol Biol Psychiatry 2005; 29(7): 1162-8.
10. Herrán A, García-Unzueta MT, Amado JA, López-Cordovilla JJ, Díez-Manrique JF, Vázquez-Barquero JL. Folate levels in psychiatric outpatients. Psychiatry Clin Neurosci 1999; 53(4): 531-3.
11. Silver H, Goodman C, Bilker W, Gur RC, Isakov V, Knoll G, et al. Impaired error monitoring contributes to face recognition deficit in schizophrenia patients. Schizophr Res 2006; 85(1-3): 151-61.
12. Muntjewerff JW, van der Put N, Eskes T, Ellenbroek B, Steegers E, Blom H, et al. Homocysteine metabolism and B-vitamins in schizophrenic patients: low plasma folate as a possible independent risk factor for schizophrenia. Psychiatry Res 2003; 121(1): 1-9.