메뉴 건너뛰기




Volumn 55, Issue 5, 2011, Pages 2092-2097

Azole resistance of Aspergillus fumigatus biofilms is partly associated with efflux pump activity

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; MESSENGER RNA; VORICONAZOLE;

EID: 79955544138     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01189-10     Document Type: Article
Times cited : (124)

References (38)
  • 1
    • 4644248400 scopus 로고    scopus 로고
    • Development and characterization of an in vivo central venous catheter Candida albicans biofilm model
    • Andes, D., et al. 2004. Development and characterization of an in vivo central venous catheter Candida albicans biofilm model. Infect. Immun. 72:6023-6031.
    • (2004) Infect. Immun. , vol.72 , pp. 6023-6031
    • Andes, D.1
  • 2
    • 77957241722 scopus 로고    scopus 로고
    • Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009
    • Bueid, A., et al. 2010. Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009. J. Antimicrob. Chemother. 65:2116-2118.
    • (2010) J. Antimicrob. Chemother. , vol.65 , pp. 2116-2118
    • Bueid, A.1
  • 3
    • 66449112829 scopus 로고    scopus 로고
    • Efflux-mediated antifungal drug resistance
    • Cannon, R. D., et al. 2009. Efflux-mediated antifungal drug resistance. Clin. Microbiol. Rev. 22:291-321.
    • (2009) Clin. Microbiol. Rev. , vol.22 , pp. 291-321
    • Cannon, R.D.1
  • 4
    • 7244243917 scopus 로고    scopus 로고
    • In vitro evolution of itraconazole resistance in Aspergillus fumigatus involves multiple mechanisms of resistance
    • da Silva Ferreira, M. E., et al. 2004. In vitro evolution of itraconazole resistance in Aspergillus fumigatus involves multiple mechanisms of resistance. Antimicrob. Agents Chemother. 48:4405-4413.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 4405-4413
    • Da Silva Ferreira, M.E.1
  • 5
    • 33745161346 scopus 로고    scopus 로고
    • Transcriptome analysis of Aspergillus fumigatus exposed to voriconazole
    • da Silva Ferreira, M. E., et al. 2006. Transcriptome analysis of Aspergillus fumigatus exposed to voriconazole. Curr. Genet. 50:32-44.
    • (2006) Curr. Genet. , vol.50 , pp. 32-44
    • Da Silva Ferreira, M.E.1
  • 6
  • 7
    • 0032856116 scopus 로고    scopus 로고
    • Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents
    • Henry, K. W., M. C. Cruz, S. K. Katiyar, and T. D. Edlind. 1999. Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents. Antimicrob. Agents Chemother. 43:1968-1974.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 1968-1974
    • Henry, K.W.1    Cruz, M.C.2    Katiyar, S.K.3    Edlind, T.D.4
  • 8
    • 67650657544 scopus 로고    scopus 로고
    • Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure
    • Howard, S. J., et al. 2009. Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure. Emerg. Infect. Dis. 15:1068-1076.
    • (2009) Emerg. Infect. Dis. , vol.15 , pp. 1068-1076
    • Howard, S.J.1
  • 9
    • 77952502309 scopus 로고    scopus 로고
    • Anti-Candida-biofilm activity of micafungin is attenuated by voriconazole but restored by pharmacological inhibition of Hsp90-related stress responses
    • Kaneko, Y., et al. 2010. Anti-Candida-biofilm activity of micafungin is attenuated by voriconazole but restored by pharmacological inhibition of Hsp90-related stress responses. Med. Mycol. 48:606-612.
    • (2010) Med. Mycol. , vol.48 , pp. 606-612
    • Kaneko, Y.1
  • 10
    • 0037334425 scopus 로고    scopus 로고
    • Effect of increasing inoculum sizes of Aspergillus hyphae on MICs and MFCs of antifungal agents by broth microdilution method
    • Lass-Flörl, C., et al. 2003. Effect of increasing inoculum sizes of Aspergillus hyphae on MICs and MFCs of antifungal agents by broth microdilution method. Int. J. Antimicrob. Agents 21:229-233.
    • (2003) Int. J. Antimicrob. Agents , vol.21 , pp. 229-233
    • Lass-Flörl, C.1
  • 11
    • 33645755409 scopus 로고    scopus 로고
    • Time course of microbiologic outcome and gene expression in Candida albicans during and following in vitro and in vivo exposure to fluconazole
    • Lepak, A., J. Nett, L. Lincoln, K. Marchillo, and D. Andes. 2006. Time course of microbiologic outcome and gene expression in Candida albicans during and following in vitro and in vivo exposure to fluconazole. Antimicrob. Agents Chemother. 50:1311-1319.
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1311-1319
    • Lepak, A.1    Nett, J.2    Lincoln, L.3    Marchillo, K.4    Andes, D.5
  • 12
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 13
    • 0035162640 scopus 로고    scopus 로고
    • Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: Novel agents for combination therapy
    • Lomovskaya, O., et al. 2001. Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob. Agents Chemother. 45:105-116.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 105-116
    • Lomovskaya, O.1
  • 14
    • 77950621398 scopus 로고    scopus 로고
    • In vivo biofilm composition of Aspergillus fumigatus
    • Loussert, C., et al. 2010. In vivo biofilm composition of Aspergillus fumigatus. Cell Microbiol. 12:405-410.
    • (2010) Cell Microbiol. , vol.12 , pp. 405-410
    • Loussert, C.1
  • 15
    • 4344693408 scopus 로고    scopus 로고
    • Adherence of Candida albicans to silicone induces immediate enhanced tolerance to fluconazole
    • Mateus, C., S. A. Crow, Jr., and D. G. Ahearn. 2004. Adherence of Candida albicans to silicone induces immediate enhanced tolerance to fluconazole. Antimicrob. Agents Chemother. 48:3358-3366.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3358-3366
    • Mateus, C.1    Crow Jr., S.A.2    Ahearn, D.G.3
  • 16
    • 34250223076 scopus 로고    scopus 로고
    • A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations
    • Mellado, E., et al. 2007. A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations. Antimicrob. Agents Chemother. 51:1897-1904.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 1897-1904
    • Mellado, E.1
  • 17
    • 22844438405 scopus 로고    scopus 로고
    • Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates
    • Meneau, I., and D. Sanglard. 2005. Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates. Med. Mycol. 43(Suppl. 1):S307-S311.
    • (2005) Med. Mycol. , vol.43 , Issue.SUPPL. 1
    • Meneau, I.1    Sanglard, D.2
  • 18
    • 73749084037 scopus 로고    scopus 로고
    • Regulation of multidrug resistance in pathogenic fungi
    • Morschhäuser, J. 2010. Regulation of multidrug resistance in pathogenic fungi. Fungal Genet. Biol. 47:94-106.
    • (2010) Fungal Genet. Biol. , vol.47 , pp. 94-106
    • Morschhäuser, J.1
  • 19
    • 0036148452 scopus 로고    scopus 로고
    • Azole cross-resistance in Aspergillus fumigatus
    • Mosquera, J., and D. W. Denning. 2002. Azole cross-resistance in Aspergillus fumigatus. Antimicrob. Agents Chemother. 46:556-557.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 556-557
    • Mosquera, J.1    Denning, D.W.2
  • 20
    • 34748871970 scopus 로고    scopus 로고
    • Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus
    • Mowat, E., J. Butcher, S. Lang, C. Williams, and G. Ramage. 2007. Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus. J. Med. Microbiol. 56:1205-1212.
    • (2007) J. Med. Microbiol. , vol.56 , pp. 1205-1212
    • Mowat, E.1    Butcher, J.2    Lang, S.3    Williams, C.4    Ramage, G.5
  • 21
    • 56649091422 scopus 로고    scopus 로고
    • Phase-dependent antifungal activity against Aspergillus fumigatus developing multicellular filamentous biofilms
    • Mowat, E., et al. 2008. Phase-dependent antifungal activity against Aspergillus fumigatus developing multicellular filamentous biofilms. J. Antimicrob. Chemother. 62:1281-1284.
    • (2008) J. Antimicrob. Chemother. , vol.62 , pp. 1281-1284
    • Mowat, E.1
  • 22
    • 67651101026 scopus 로고    scopus 로고
    • The characteristics of Aspergillus fumigatus mycetoma development: Is this a biofilm?
    • Mowat, E., C. Williams, B. Jones, S. McChlery, and G. Ramage. 2009. The characteristics of Aspergillus fumigatus mycetoma development: is this a biofilm? Med. Mycol. 47:(Suppl. 1)S120-S126.
    • (2009) Med. Mycol. , vol.47 , Issue.SUPPL. 1
    • Mowat, E.1    Williams, C.2    Jones, B.3    McChlery, S.4    Ramage, G.5
  • 23
    • 0041764578 scopus 로고    scopus 로고
    • Mechanism of fluconazole resistance in Candida albicans biofilms: Phase-specific role of efflux pumps and membrane sterols
    • Mukherjee, P. K., J. Chandra, D. M. Kuhn, and M. A. Ghannoum. 2003. Mechanism of fluconazole resistance in Candida albicans biofilms: phase-specific role of efflux pumps and membrane sterols. Infect. Immun. 71:4333-4340.
    • (2003) Infect. Immun. , vol.71 , pp. 4333-4340
    • Mukherjee, P.K.1    Chandra, J.2    Kuhn, D.M.3    Ghannoum, M.A.4
  • 24
    • 0037659190 scopus 로고    scopus 로고
    • Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole
    • Nascimento, A. M., et al. 2003. Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole. Antimicrob. Agents Chemother. 47:1719-1726.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1719-1726
    • Nascimento, A.M.1
  • 25
    • 77955355113 scopus 로고    scopus 로고
    • Role of Fks1p and matrix glucan in Candida albicans biofilm resistance to an echinocandin, pyrimidine, and polyene
    • Nett, J. E., K. Crawford, K. Marchillo, and D. R. Andes. 2010. Role of Fks1p and matrix glucan in Candida albicans biofilm resistance to an echinocandin, pyrimidine, and polyene. Antimicrob. Agents Chemother. 54:3505-3508.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 3505-3508
    • Nett, J.E.1    Crawford, K.2    Marchillo, K.3    Andes, D.R.4
  • 26
    • 67650665320 scopus 로고    scopus 로고
    • Time course global gene expression analysis of an in vivo Candida biofilm
    • Nett, J. E., A. J. Lepak, K. Marchillo, and D. R. Andes. 2009. Time course global gene expression analysis of an in vivo Candida biofilm. J. Infect. Dis. 200:307-313.
    • (2009) J. Infect. Dis. , vol.200 , pp. 307-313
    • Nett, J.E.1    Lepak, A.J.2    Marchillo, K.3    Andes, D.R.4
  • 27
    • 28644434509 scopus 로고    scopus 로고
    • Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
    • Nierman, W. C., et al. 2005. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 438:1151-1156.
    • (2005) Nature , vol.438 , pp. 1151-1156
    • Nierman, W.C.1
  • 28
    • 33745755772 scopus 로고    scopus 로고
    • A prospective randomized trial of itraconazole vs fluconazole for the prevention of fungal infections in patients with acute leukemia and hematopoietic stem cell transplant recipients
    • Oren, I., et al. 2006. A prospective randomized trial of itraconazole vs fluconazole for the prevention of fungal infections in patients with acute leukemia and hematopoietic stem cell transplant recipients. Bone Marrow Transplant. 38:127-134.
    • (2006) Bone Marrow Transplant. , vol.38 , pp. 127-134
    • Oren, I.1
  • 29
    • 33747154459 scopus 로고    scopus 로고
    • Multidrug-resistance efflux pumps-not just for resistance
    • Piddock, L. J. 2006. Multidrug-resistance efflux pumps-not just for resistance. Nat. Rev. Microbiol. 4:629-636.
    • (2006) Nat. Rev. Microbiol. , vol.4 , pp. 629-636
    • Piddock, L.J.1
  • 30
    • 40849093036 scopus 로고    scopus 로고
    • Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: Posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin
    • Raad, I. I., et al. 2008. Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin. Leukemia 22:496-503.
    • (2008) Leukemia , vol.22 , pp. 496-503
    • Raad, I.I.1
  • 31
    • 0035992139 scopus 로고    scopus 로고
    • Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms
    • Ramage, G., S. Bachmann, T. F. Patterson, B. L. Wickes, and J. L. Lopez-Ribot. 2002. Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms. J. Antimicrob. Chemother. 49:973-980.
    • (2002) J. Antimicrob. Chemother. , vol.49 , pp. 973-980
    • Ramage, G.1    Bachmann, S.2    Patterson, T.F.3    Wickes, B.L.4    Lopez-Ribot, J.L.5
  • 32
    • 33646898182 scopus 로고    scopus 로고
    • Voriconazole treatment for subacute invasive and chronic pulmonary aspergillosis
    • Sambatakou, H., B. Dupont, H. Lode, and D. W. Denning. 2006. Voriconazole treatment for subacute invasive and chronic pulmonary aspergillosis. Am. J. Med. 119:527, e17-e24.
    • (2006) Am. J. Med. , vol.119
    • Sambatakou, H.1    Dupont, B.2    Lode, H.3    Denning, D.W.4
  • 33
    • 77952597776 scopus 로고    scopus 로고
    • Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling
    • Snelders, E., A. Karawajczyk, G. Schaftenaar, P. E. Verweij, and W. J. Melchers. 2010. Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling. Antimicrob. Agents Chemother. 54:2425-2430.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 2425-2430
    • Snelders, E.1    Karawajczyk, A.2    Schaftenaar, G.3    Verweij, P.E.4    Melchers, W.J.5
  • 34
    • 56749159784 scopus 로고    scopus 로고
    • Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism
    • Snelders, E., et al. 2008. Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism. PLoS Med. 5:e219.
    • (2008) PLoS Med. , vol.5
    • Snelders, E.1
  • 35
    • 74949097747 scopus 로고    scopus 로고
    • The effects of antifungal agents to conidial and hyphal forms of Aspergillus fumigatus
    • van de Sande, W. W., M. Tavakol, W. van Vianen, and I. A. Bakker-Woudenberg. 2010. The effects of antifungal agents to conidial and hyphal forms of Aspergillus fumigatus. Med. Mycol. 48:48-55.
    • (2010) Med. Mycol. , vol.48 , pp. 48-55
    • Van De Sande, W.W.1    Tavakol, M.2    Van Vianen, W.3    Bakker-Woudenberg, I.A.4
  • 36
    • 33846959131 scopus 로고    scopus 로고
    • Voriconazole and multidrug resistance in Candida albicans
    • Wakiec, R., et al. 2007. Voriconazole and multidrug resistance in Candida albicans. Mycoses 50:109-115.
    • (2007) Mycoses , vol.50 , pp. 109-115
    • Wakiec, R.1
  • 37
    • 33845356887 scopus 로고    scopus 로고
    • Comparative in vivo activity of BAL4815, the active component of the prodrug BAL8557, in a neutropenic murine model of disseminated Aspergillus flavus
    • Warn, P. A., et al. 2006. Comparative in vivo activity of BAL4815, the active component of the prodrug BAL8557, in a neutropenic murine model of disseminated Aspergillus flavus. J. Antimicrob. Chemother. 58:1198-1207.
    • (2006) J. Antimicrob. Chemother. , vol.58 , pp. 1198-1207
    • Warn, P.A.1
  • 38
    • 0030757227 scopus 로고    scopus 로고
    • Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus
    • White, T. C. 1997. Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrob. Agents Chemother. 41:1482-1487.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1482-1487
    • White, T.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.