Material characterization and computer model simulation of low density polyurethane foam used in a rodent traumatic brain injury model

Journal of Neuroscience Methods

Volumn 198, Issue 1, 2011, Pages 93-98

  Zhang, Liying ^a   Gurao, Manish ^a   Yang, King H ^a   King, Albert I ^a  

^a Wayne State University   (United States)

Author keywords

Compression test; Finite element modeling; Low density polyurethane foam; Rate dependency; Rodent head impact acceleration device; Traumatic brain injury

Indexed keywords

POLYURETHAN FOAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; FINITE ELEMENT ANALYSIS; NONHUMAN; PRIORITY JOURNAL; STRESS STRAIN RELATIONSHIP; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN INJURIES; COMPUTER SIMULATION; DISEASE MODELS, ANIMAL; POLYURETHANES; RODENTIA; SPECIES SPECIFICITY; STRESS, MECHANICAL;

EID: 79955504774     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2011.03.024     Document Type: Article

References (28)

1. Cernak I., Chapman S.M., Hamlin G.P., Vink R. Temporal characterisation of pro- and anti-apoptotic mechanisms following diffuse traumatic brain injury in rats. J Clin Neurosci 2002, 9(5):565-572.
2. Chang F.S., DeSilva C.N. Unified constitutive equation of foam materials. J Eng Mater Technol 1998, 120:212-216.
3. Davies O.L., Mills N.J. The rate dependence of confor polyurethane foams. Cell Polym 1999, 8(2):117-136.
4. Fei Z., Zhang X., Bai H.M. Metabotropic glutamate receptor antagonists and agonists: potential neuroprotectors in diffuse brain injury. J Clin Neurosci 2006, 13:1023-1027.
5. Foda M.A., Marmarou A. A new model of diffuse axonal injury in rats. Part II. Morphological characteristic. J Neurosurg 1994, 8:301-313.
6. Gibson L.J., Ashby M.F. Cellular solids: structure and properties 1988, Pergamon Press, New York.
7. Hager S.L., Craig T.A. Fatigue testing of high performance flexible polyurethane foam. J Cell Plast 1992, 28:284-301.
8. Heath D.L., Vink R. Improved motor outcome in response to magnesium therapy received up to 24h after traumatic diffuse axonal brain injury in rats. J Neurosurg 1999, 90:504-509.
9. Hosford W.F., Caddell R.M. Metal forming mechanics and metallurgy 1993, PTR Prentice Hall, New Jersey, p. 80-1.
10. Kallakuri S., Cavanaugh J.M., Ozaktay A.C., Takebayashi T. The effect of varying impact energy on diffuse axonal injury in the rat brain: a preliminary study. Exp Brain Res 2003, 148(4):419-424.
11. Kim J.S., Walter M.E., Lee J.K. Modeling mechanical response of intumescent mat material at room temperature. Int. J Mech Sci 2002, 2285-2325.
12. Lammie G.A., Piper I.R., Thomson D., Brannan F. Neuropathologic characterization of a rodent model of closed head injury-addition of clinically relevant secondary insults does not significantly potentiate brain damage. J Neurotrauma 1999, 16(7):603-615.
13. Marmarou A., Foda M.A., Van den Brink W., Campbell J., Kita H., Demetriadou K. A new model of diffuse brain injury in rats. Part I. Pathophysiology and biomechanics. J. Neurosurg 1994, 80:291-300.
14. Mills N.J., Gilchrist A. Modelling the indentation of low density polymer foams. Cell Polym 2000, 19:389-412.
15. Mills N.J., Lyn G. Modeling of air flow in impacted polyurethane foam. Cell Polym 2002, 21(5):343-367.
16. Piper I.R., Miller J.D., Thomson D. Monitoring weight drop velocity and foam stiffness as an aid to quality control of a rodent model of impact acceleration neurotrauma. J Neurosci Methods 1996, 69:171-174.
17. Povlishock J.T., Christman C.W. The pathobiology of traumatically induced axonal injury in animals and humans: a review of current thoughts. J Neurotrauma 1995, 12(4):555-564.
18. Rehkopf J.D., McNeice G.M., Brodland G.W., Kuczynski E.T., Kerman M. Dynamic behavior of an automotive polyurethane foam under multiple compression cycles. Proc international congress and expos 1994, SAE technical paper no. 940876.
19. Schmidt R.H., Scholten K.J., Maughan P.H. Cognitive impairment and synaptosomal choline uptake in rats following impact acceleration injury. J Neurotrauma 2000, 17:1129-1139.
20. Sengul G., Takci E., Malcok U.A., Akar A., Erdogan F., Kadioglu H.H., et al. A preliminary histopathological study of the effect of agmatine on diffuse brain injury in rats. J Clin Neurosci 2008, 15:1125-1129.
21. Stone J.R., Okonkwo D.O., Dialo A.O., Rubin D.G., Mutlu L.K., Povlishock J.T., et al. Impaired axonal transport and altered axolemmal permeability occur in distinct populations of damaged axons following traumatic brain injury. J Exp Neurol 2004, 190:59-69.
22. Suresh S. Fatigue of materials 1991, Cambridge University Press, Cambridge, Britain.
23. Tavazzi B., Signoretti S., Lazzarino G., Amorini A.M., Delfini R., Cimatti M., et al. Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats. Neurosurgery 2005, 56:582-589.
24. Vagnozzi R., Tavazzi B., Signoretti S., Amorini A.M., Belli A., Cimatti M., et al. Temporal window of metabolic brain vulnerability to concussions: mitochondrial-related impairment - part I. Neurosurgery 2007, 61:379-388.
25. Vorspohl K., Mertes J., Zschiesche R., Lutte H.D., Drumm R. Time dependence of hardness of cold cure molded flexible foams and its importance for system development. J Cell Plast 1994, 30:361-373.
26. Youssef S., Maire E., Gaertner R. Finite element modeling of the actual structure of cellular material determined by X-ray tomography. Acta Mater 2005, 53:719-730.
27. Zhang L., Mao H., Yang K.H., King A.I. Heterogeneous mechanical properties of brain tissue contribute to local variations in mechanical response in the rat hippocampus. Proc ASME Bioengineering Conference No. 157381 2006.
28. Zhang L., Zhou R., Neng Y. Biomechanical response of impact acceleration-induced traumatic axonal injury: rat head model development and injury localization. J Neurotrauma 2010, 26:42.