Label-free imaging of human breast tissues using coherent anti-Stokes Raman scattering microscopy

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7903, Issue , 2011, Pages

  Yang, Yaliang ^a   Gao, Liang ^a,c   Wang, Zhiyong ^a   Thrall, Michael J ^b   Luo, Pengfei ^a   Wong, Kelvin K ^a,b   Wong, Stephen T C ^a,b,c  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b HOUSTON METHODIST HOSPITAL   (United States)

^c Rice University   (United States)

Author keywords

Breast cancer; Coherent anti Stokes Raman scattering microscopy; Differential diagnosis; Nonlinear optical microscopy

Indexed keywords

BENIGN TISSUES; BIOMEDICAL APPLICATIONS; BREAST CANCER; COHERENT ANTI-STOKES RAMAN SCATTERING; COHERENT ANTI-STOKES RAMAN SCATTERING MICROSCOPY; CURRENT IMAGING; DIAGNOSTIC METHODS; DIFFERENTIAL DIAGNOSIS; EX-VIVO; FAST IMAGING; HIGH COSTS; HIGH DEMAND; HUMAN BREAST TISSUE; IMAGING SPEED; IN-VIVO; LABEL FREE; MEDICAL EXPENSE; MORPHOLOGICAL FEATURES; NONLINEAR OPTICAL MICROSCOPY; PILOT STUDIES; REALTIME IMAGING; SPATIAL RESOLUTION; SUB-WAVELENGTH; VIDEO RATES;

COHERENT SCATTERING; DIAGNOSIS; DISEASES; HISTOLOGY; IMAGING TECHNIQUES; OPTICAL DATA STORAGE; OPTICAL INSTRUMENTS; OPTICAL MICROSCOPY; RAMAN SPECTROSCOPY; TISSUE;

RAMAN SCATTERING;

EID: 79955503624     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.871063     Document Type: Conference Paper

References (20)

1. Melonie, H., "Deaths: leading causes for 2004, " Natl. Vital. Stat. Rep. 56, 1-95 (2007).
2. American Cancer Society, "Cancer facts & figures 2010, " Atlanta: American Cancer Society (2010).
3. Kumar, K. K., Chowdary, M. V. P., Mathew, S., Rao, L., Krishna, C. M. and Kurine, J., "Raman spectroscopic diagnosis of breast cancers: evaluation of models, " J. Raman Spectros. 39, 1276-1282 (2008).
4. Gupta, D. and Layfield, L. J., "Prevalence of inter-institutional anatomic pathology slide review: a survey of current practice, " Am. J. Surg. Pathol. 24, 280-284 (2000). (Pubitemid 30078717)
5. Liberman, L., Dershaw, D. D., Rosen, P. P., Abramson, A. F., Deutch, B. M. and Hann, L. E., "Stereotaxic 14 gauge breast biopsy: how many core biopsy specimens are needed?" Radiology 192, 793-795 (1994). (Pubitemid 24266799)
6. Chowdary, M. V., Kumar, K. K., Kurien, J., Mathew, S. and Krishna, C. M., "Discrimination of normal, benign, and malignant breast tissues by Raman spectroscopy, " Biopolymers 83, 556-569 (2006). (Pubitemid 44851668)
7. Haka, A. S., Shafer-Peltier, K. E., Fitzmaurice, M., Crowe, J., Dasari, R. R. and Feld, M. S., "Diagnosing breast cancer by using Raman spectroscopy, " PNAS 102, 12371-12376 (2005). (Pubitemid 41266366)
8. 2 laser excited autofluorescence spectroscopy, " Lasers Surg. Med. 21, 417-422 (1997). (Pubitemid 27481401)
9. Majumder, S. K., Gupta, P. K., Jain, B. and Uppal, A., "UV excited autofluorescence spectroscopy of human breast tissues for discriminating cancerous tissue from benign tumor and normal tissue, " Lasers Life Sci. 8, 249- 264 (1998).
10. Yang, Y., Katz, A., Celmer, E. J., Zurawska-Szczepaniak, M. and Alfano, R. R., "Fundamental differences of excitation spectrum between malignant and benign breast tissues, " Photochem. Photobiol. 66, 518-522 (1997). (Pubitemid 127470200)
11. Haka, A. S., Volynskaya, Z., Gardecki, J. A., Nazemi, J., Lyons, J., Hicks, D., Fitzmaurice, M., Dasari, R. R., Crowe, J. P. and Feld, M. S., "In vivo margin assessment during partial mastectomy breast surgery using Raman spectroscopy, " Cancer Res. 66, 3317-3322 (2006).
12. Nguyen, F. T., Zysk, A. M., Chaney, E. J., Kotynek, J. G., Oliphant, U. J., Bellafiore, F. J., Rowland, K. M., Johnson, P. A. and Boppart, S. A., "Intraoperative evaluation of breast tumor margins with optical coherence tomography, " Cancer Res. 69, 8790-8796 (2009).
13. Wang, Z., Yang, Y., Luo, P., Gao, L., Wong, K. K. and Wong, S. T. C., "Delivery of picosecond lasers in multimode fibers for coherent anti-Stokes Raman scattering imaging, " Opt. Express 18, 13017-13028 (2010).
14. Cheng, J. X. and Xie, X. S., "Coherent anti-Stokes Raman scattering microscopy: instrumentation, theory, and applications, " J. Phys. Chem. B 108, 827-840 (2004).
15. Ganikhanov, F., Evans, C. L., Saar, B. G. and Xie, X. S., "High sensitivity vibrational imaging with frequency modulation coherent anti-Stokes Raman scattering (FM CARS) microscopy, " Opt. Lett. 31, 1872-1874 (2006). (Pubitemid 44048932)
16. Evans, C. L., Potma, E. O., Puoris'haag, M., Côté, D., Lin, C. P. and Xie, X. S., "Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy, " PNAS 102, 16807-16812 (2005). (Pubitemid 41688858)
17. Nan, X., Cheng, J. X. and Xie, X. S., "Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscopy, " J. Lipid Res. 44, 2202-2208 (2003). (Pubitemid 37509636)
18. Cheng, J. X., "Coherent anti-stokes Raman scattering microscopy, " Appl. Spectrosc. 61, 197A-208A (2007).
19. Muller, M. and Zumbusch, A., "Coherent anti-Stokes Raman scattering microscopy, " Chem. Phys. Chem. 8, 2156-2170 (2007).
20. Evans, C. L., Xu, X., Kesari, S., Xie, X. S., Wong, S. T. C. and Young, G. S., "Chemically-selective imaging of brain structures with CARS microscopy, " Opt. Express 15, 12076-12087 (2007). (Pubitemid 47460072)