Pro: The illegitimate crusade against corticosteroids for severe H1N1 pneumonia

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 9, 2011, Pages 1125-1126

  Annane, Djillali ^a  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ALBUMIN; CORTICOSTEROID; CYTOKINE; DOPAMINE; GLUCOCORTICOID RECEPTOR ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANTIOXIDANT ACTIVITY; AUTHOR; AUTOPSY; BRONCHIOLITIS; CELL MIGRATION; CHEMOKINESIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ASSESSMENT; COHORT ANALYSIS; COLLOID; CYTOKINE RELEASE; CYTOSOL; CYTOTOXICITY; DISEASE ASSOCIATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG EXPOSURE; DRUG SAFETY; FRANCE; HEMATOLOGIC MALIGNANCY; HOSPITAL INFECTION; HUMAN; IMMUNOCOMPETENT CELL; INFECTION; INFECTION RISK; INFLUENZA VIRUS A H1N1; INNATE IMMUNITY; INTENSIVE CARE UNIT; LUNG ALVEOLITIS; LUNG HEMORRHAGE; LUNG PARENCHYMA; MACROPHAGE; MORTALITY; NECROTIZING BRONCHIOLITIS; NEOPLASM; NEUTROPHIL; PANDEMIC; PHAGOCYTOSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK REDUCTION; SEPSIS; SOUTH KOREA; SUPERINFECTION; TRANSACTIVATION; TREATMENT DURATION; VENTILATOR ASSOCIATED PNEUMONIA; VIRUS PNEUMONIA;

ACUTE LUNG INJURY; ADRENAL CORTEX HORMONES; CROSS INFECTION; HOSPITAL MORTALITY; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTENSIVE CARE; PNEUMONIA;

EID: 79955502350     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201102-0345ED     Document Type: Review

References (20)

1. Brun-Buisson C, Richard JC, Mercat A, Thiébaut A, Brochard L. Early corticosteroids in severe Influenza A/H1N1 pneumonia and acute respiratory distress syndrome. Am J Respir Crit Care Med 2011;183:1200-1206.
2. Kim SH, Hong SB, Yun SC, Choi WI, Ahn JJ, Lee YJ, Lee HB, Lim CM, Koh Y. Corticosteroid treatment in critically ill patients with pandemic influenza A/H1N1 2009 infection. Am J Respir Crit Care Med 2011;183:1207-1214.
3. Bautista E, Chotpitayasunondh T, Gao Z, Harper SA, Shaw M, Uyeki TM, Zaki SR, Hayden FG, Hui DS, Kettner JD, et al.; Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza. Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med 2010;362:1708-1719.
4. Mauad T, Hajjar LA, Callegari GD, da Silva LF, Schout D, Galas FR, Alves VA, Malheiros DM, Auler JO Jr, Ferreira AF, et al. Lung pathology in fatal novel human influenza A (H1N1) infection. Am J Respir Crit Care Med 2010;181:72-79.
5. Kobasa D, Jones SM, Shinya K, Kash JC, Copps J, Ebihara H, Hatta Y, Kim JH, Halfmann P, Hatta M, et al. Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature 2007;445:319-323.
6. Vlahos R, Stambas J, Bozinovski S, Broughton BR, Drummond GR, Selemidis S. Inhibition of nox2 oxidase activity ameliorates influenza a virus-induced lung inflammation. PLoS Pathog 2011;7:e1001271.
7. Barczyk K, Ehrchen J, Tenbrock K, Ahlmann M, Kneidl J, Viemann D, Roth J. Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3. Blood 2010;116:446-455.
8. Ottolini M, Blanco J, Porter D, Peterson L, Curtis S, Prince G. Combination antiinflammatory and antiviral therapy of influenza in a cotton rat model. Pediatr Pulmonol 2003;36:290-294. (Pubitemid 37129767)
9. Quispe-Laime AM, Bracco JD, Barberio PA, Campagne CG, Rolfo VE, Umberger R, Meduri GU. H1N1 influenza A virus-associated acute lung injury: response to combination oseltamivir and prolonged corticosteroid treatment. Intensive Care Med 2010;36:33-41.
10. Lee KY, Rhim JW, Kang JH. Hyperactive immune cells (T cells) may be responsible for acute lung injury in influenza virus infections: a need for early immune-modulators for severe cases. Med Hypotheses 2011;76:64-69.
11. Linko R, Pettilä1 V, Ruokonen E, Varpula T, Sari Karlsson S, Tenhunen J, Reinikainen M, Saarinen K, Perttilä J, Parviainen I, et al.; FINNH1N1-study group. Steroid treatment in patients with influenza A(H1N1) infection in Finnish ICUs: an observational study. Acta Anesth Scand (In press)
12. Martin-Loeches I, Lisboa T, Rhodes A, Moreno RP, Silva E, Sprung C, Chiche JD, Barahona D, Villabon M, Balasini C, et al.; ESICM H1N1 Registry Contributors. Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection. Intensive Care Med 2011;37:272-283.
13. Viasus D, Ramón Paño-Pardo J, Cordero E, Campins A, López-Medrano F, Villoslada A, Fariñas MC, Moreno A, Rodríguez-Baño J, Antonio Oteo J, et al.; Novel Influenza A (H1N1) Study Group of the Spanish Network for Research in Infectious Diseases (REIPI). Effect of immunomodulatory therapies in patients with pandemic influenza A (H1N1) 2009 complicated by pneumonia. J Infect 2011;62:193-199.
14. Falagas ME, Vouloumanou EK, Baskouta E, Rafailidis PI, Polyzos K, Rello J. Treatment options for 2009 H1N1 influenza: evaluation of the published evidence. Int J Antimicrob Agents 2010;35:421-430.
15. Connors AF Jr, Speroff T, Dawson NV, Thomas C, Harrell FE Jr, Wagner D, Desbiens N, Goldman L, Wu AW, Califf RM, et al.; SUPPORT Investigators The effectiveness of right heart catheterization in the initial care of critically ill patients. JAMA 1996;276:889-897.
16. Harvey S, Stevens K, Harrison D, Young D, Brampton W, McCabe C, Singer M, Rowan K. An evaluation of the clinical and cost-effectiveness of pulmonary artery catheters in patient management in intensive care: a systematic review and a randomised controlled trial. Health Technol Assess 2006;10:iii-iv, ix-xi, 1-133.
17. Glynn RJ, Schneeweiss S, Stürmer T. Indications for propensity scores and review of their use in pharmacoepidemiology. Basic Clin Pharmacol Toxicol 2006;98:253-259.
18. Cook EF, Goldman L. Performance of tests of significance based on stratification by a multivariate confounder score or by a propensity score. J Clin Epidemiol 1989;42:317-324. (Pubitemid 19133717)
19. Steinberg KP, Hudson LD, Goodman RB, Hough CL, Lanken PN, Hyzy R, Thompson BT, Ancukiewicz M; National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med 2006;354:1671-1684.
20. Roquilly A, Mahe PJ, Seguin P, Guitton C, Floch H, Tellier AC, Merson L, Renard B, Malledant Y, Flet L, et al. Hydrocortisone therapy for corticosteroid insufficiency related to trauma: The HYPOLYT study. JAMA 2011;305:1201-1209.