In vivo activity of Sapindus saponaria against azole-susceptible and -resistant human vaginal Candida species

BMC Complementary and Alternative Medicine

Volumn 11, Issue , 2011, Pages

  Damke, Edílson ^a   Tsuzuki, Joyce K ^a   Cortez, Diógenes A G ^a   Ferreira, Izabel C P ^a   Bertoni, Thâmara A ^a   Batista, Márcia R ^a   Donati, Lucélia ^b   Svidzinski, Terezinha I E ^a   Consolaro, Márcia E L ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

in vivo; Sapindus saponariavaginal yeastsantifungal activity

Indexed keywords

ACYCLIC OLIGOGLYCOSIDE 1; ANTIFUNGAL AGENT; FLUCONAZOLE; HEDERAGENIN 3 O (3,4 DI O ACETYL BETA DEXTRO XYLOPYRANOSYL) (1-3) ALPHA LEVO RAMNOPYRANOSYL (1-2) ALPHA LEVO ARABINOPYRANOSIDE; HEDERAGENIN 3 O (4 O ACETYL BETA DEXTRO XYLOPYRANOSYL) (1-3) ALPHA LEVO RAMNOPYRANOSYL (1-2) ALPHA LEVO RABINOPYRANOSIDE; ITRACONAZOLE; PLANT EXTRACT; PLANT GLYCOSIDE; SAPINDUS SAPONARIA EXTRACT; SAPONIN; UNCLASSIFIED DRUG; PYRROLE DERIVATIVE; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BROTH DILUTION; CANDIDA ALBICANS; CANDIDA GLABRATA; CARBON NUCLEAR MAGNETIC RESONANCE; COLONY FORMING UNIT; COMPETITIVE INHIBITION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; FUNGAL STRAIN; FUNGICIDAL ACTIVITY; FUNGUS ISOLATION; HELA CELL; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; IN VIVO STUDY; MEDICINAL PLANT; MINIMUM FUNGICIDE CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SAPINDUS SAPONARIA; SCANNING ELECTRON MICROSCOPY; TREATMENT DURATION; VAGINA CANDIDIASIS; VAGINA EPITHELIUM; ANIMAL; BRAZIL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; FRUIT; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; SAPINDACEAE; UTERINE CERVIX; WISTAR RAT;

ANIMALS; ANTIFUNGAL AGENTS; AZOLES; BRAZIL; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDIASIS, VULVOVAGINAL; CERVIX UTERI; EPITHELIAL CELLS; FEMALE; FLUCONAZOLE; FRUIT; HELA CELLS; HUMANS; ITRACONAZOLE; MICROBIAL SENSITIVITY TESTS; PLANT EXTRACTS; RATS; RATS, WISTAR; SAPINDUS; SAPONINS; TRITERPENES;

EID: 79955497211     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-11-35     Document Type: Article

References (29)

1. Matos FJA. Farmácias Vivas: sistema de utilização de plantas medicinais projetado para pequenas comunidades. 2002, Fortaleza: Ed. UFC.
2. Ribeiro A, Zani CL, Alves TMA, Mendes NM, Hamburger M, Hostettmann K. Molluscicidal saponins from the pericarp of Sapindus saponaria. Int J Pharmacognosy 1995, 33:177-180.
3. Albiero ALM, Sertié JAA, Bacchi EM. Antiulcer activity of Sapindus saponaria L. in the rat. J Ethnopharmacol 2002, 82:41-44. 10.1016/S0378-8741(02)00094-6, 12169404.
4. Murgu M, Rodrigues-Filho E. Hydroxilation of a hederagenin derived saponin by a Xylareaceous fungus found in fruits of Sapindus saponaria. J Braz Chem Soc 2006, 17:1281-1290.
5. Tzuzuki JK, Svidzinski TIE, Shinobu CS, Silva LFA, Rodrigues-Filho E, Cortez DAG, Ferreira ICP. Antifungal activity of the extracts and saponins from Sapindus saponaria L. Anais Ac Bras Ciências 2007, 79:577-583.
6. Sobel JD. Vulvovaginal candidosis. Lancet 2007, 369:1961-1971. 10.1016/S0140-6736(07)60917-9, 17560449.
7. Corsello S, Spinillo A, Osnengo G, Penna C, Guaschino S. Beltrame: An epidemiological survey of vulvovaginal candidiasis in Italy. Eur J Obstet Gynecol Reprod Biol 2003, 110:66-72. 10.1016/S0301-2115(03)00096-4, 12932875.
8. Sojakova M, Liptajova D, Borovsky M, Subik J. Fluconazole and itraconazole susceptibility of vaginal yeasts isolated from Slovakia. Mycopathologia 2004, 157:163-169.
9. Dota KFD, Shinobu CS, Patussi EV, Consolaro MEL, Svidzinski TIE. Susceptibility to vaginal yeast in most used antifungal in Maringá, Paraná, Brazil. Acta Bioquim Clin Latinoam 2008, 110:66-72.
10. Larone DH. Medically important fungi. A guide to identification. 2005, Washington: ASM Press.
11. Kurtzmann CP, Fell FW. The yeast. A taxonomy study. 1998, Amsterdam: Elsevier.
12. Sugita T, Kurosaka S, Yajitate M, Sato H, Nishikawa A. Extracellular proteinase and phospolipase activity of three genotypic strains of a human pathogenic yeast, Candida albicans. Microbiol Immunol 2002, 46:881-883.
13. Clinical Laboratory Standard Institute Reference method for broth dillution antifungal susceptibility testing for yeasts: approved standard M27-A2. 2002, CLSI, Wayne, PA, USA, Clinical Laboratory Standard Institute.
14. Dota KFD, Faria MGI, Bruschi ML, Pelloso SM, Consolaro MEL, Svidzinski TIE. Antifungal activity of propolis extract against yeasts isolated from vaginal exudates. J Alt Compl Med 2010, 16(3):285-290.
15. De Bernardis F, Lucciarini R, Boccanera M, Amantini C, Arancia S, Morrone S, Mosca M, Cassone A, Santoni G. Phenotypic and functional characterization of vaginal dendritic cells in a rat model of Candida albicans vaginitis. Infec Immun 2006, 74:4282-4294.
16. Lee MW, Kim S, Han DR. Antifungal activity of modified hederagenin from the leaves of Kalopanax pictum var. Chinese. Biol Pharm Bull 2001, 24:718-719. 10.1248/bpb.24.718, 11411568.
17. Du Z, Zhu N, Ze-Ren-Wang-Mu N, Shen Y. Two new antifungal saponins from the Tibetan herbal medicine Clematis tangutica. Planta Med 2003, 69:547-551.
18. Tamura Y, Mizutani K, Ikeda T, OHTANI K, KASAI R, YAMASAKI K, TANAKA O. Antimicrobial activies of saponins of pericarps of Sapindus mukurossi on dermatophytes. Nat Med 2001, 55(1):11-16.
19. Barile E, Bonanomi G, Antignani V, Zolfaghari B, Sajjadi SE, Scala F, Lanzotti V. Saponins from Allium minutiflorum with antifungal activity. Phitochem 2007, 68(5):596-603.
20. Kuete V, Tangmouo JG, PenlapBeng V, Ngounou FN, Lontsi D. Antimicrobial activity of the methanolic extract from from the stem bark of Tridesmostemon omphalocarpoides (Sapotaceae). J Ethn 2006, 104:8-11.
21. Mandal P, Sinha Babu SP, Mandal NC. Antimicrobial activity of saponins from Acacia auriculiformis. Fitoter 2005, 76:462-465.
22. Francis G, Kerem Z, Makkar HPS, Becker K. The biological action saponins in animal systems: a review. British J Nutr 2002, 88:587-605.
23. Ferrer J. Vaginal candidosis: epidemiological and etiological factors. I J Gynaecol Obstet 2000, 71(1):21-27.
24. Duarte MCT, Figueira M, Sartorato A, Rehder VLG, Delarmelina C. Anti-Candida activity of brazilian medicinal plants. J Ethnoph 2005, 97:305-311.
25. Ferraza MHSH, Maluf MLF, Consolaro MEL, Shinobu CS, Svidzinski TIE. Caracterização de leveduras isoladas da vagina e sua associação com candidíase vulvovaginal em duas cidades do sul do Brasil. Rev Bras Ginecol obstet 2005, 27(2):58-63.
26. Consolaro MEL, Albertoni TA, Yoshida CS, Mazucheli J, Peralta RM, Svidzinski TIE. Correlation of Candida species and symptoms among patients with vulvovaginal candidiasis in Maringa, Parana, Brazil. Rev Iberoam Micol 2004, 21:202-205.
27. Jacobs WA. The saponin occurring in Sapindus saponaria L. and Sapindus mukorossi utilis. J Biol Chem 1925, 64:379-381.
28. Quetin-Leclercq J, Elias R, Balansard G, Bassleer R, Angenot L. Cytotoxic activity of some triterpenoid saponins. Planta Med 1992, 58(3):279-281. 10.1055/s-2006-961456, 1409985.
29. Meyer ALA, Sarragiotto MH, Fujimura A, Bacchi EM. Cytotoxic activity of Sapindus saponaria L. fruits on Ehrlich ascitic tumor cells. Acta Farmac Bonaer 2001, 20(3):169-171.