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Volumn 25, Issue 3, 2011, Pages 413-418

Fozivudine tidoxil as single-agent therapy decreases plasma and cell-associated viremia during acute feline immunodeficiency virus infection

Author keywords

Acquired immunodeficiency syndrome; Antiretroviral therapy; Lentivirus; Zidovudine

Indexed keywords

ANTIVIRUS AGENT; DRUG DERIVATIVE; FOZIVUDINE TIDOXIL; LIPID; ZIDOVUDINE;

EID: 79955487456     PISSN: 08916640     EISSN: 19391676     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2011.0699.x     Document Type: Article
Times cited : (12)

References (34)
  • 1
    • 0023137671 scopus 로고
    • Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome
    • Pedersen NC, Ho E, Brown ML, Yamamoto JK. Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome. Science 1987;235:790-793.
    • (1987) Science , vol.235 , pp. 790-793
    • Pedersen, N.C.1    Ho, E.2    Brown, M.L.3    Yamamoto, J.K.4
  • 2
    • 34648860955 scopus 로고    scopus 로고
    • FIV as a model of AIDS pathogenesis studies
    • Friedman H, Specter S, Bendinelli M, eds. New York: Springer.
    • Vahlenkamp TW, Tompkins MB, Tompkins WA. FIV as a model of AIDS pathogenesis studies. In: Friedman H, Specter S, Bendinelli M, eds. In Vivo Models of HIV Disease and Control. New York: Springer; 2006:239-273.
    • (2006) In Vivo Models of HIV Disease and Control , pp. 239-273
    • Vahlenkamp, T.W.1    Tompkins, M.B.2    Tompkins, W.A.3
  • 3
    • 0030893913 scopus 로고    scopus 로고
    • Mucosal transmission of cell-associated and cell-free feline immunodeficiency virus
    • Burkhard M, Obert LA, O'Neil LL, et al. Mucosal transmission of cell-associated and cell-free feline immunodeficiency virus. AIDS Res Hum Retroviruses 1997;13:347-355.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 347-355
    • Burkhard, M.1    Obert, L.A.2    O'Neil, L.L.3
  • 4
    • 0028796099 scopus 로고
    • Feline immunodeficiency virus: An interesting model for AIDS studies and an important cat pathogen
    • Bendinelli M, Pistello M, Lombardi S, et al. Feline immunodeficiency virus: An interesting model for AIDS studies and an important cat pathogen. Clin Microbiol Rev 1995;8:87-112.
    • (1995) Clin Microbiol Rev , vol.8 , pp. 87-112
    • Bendinelli, M.1    Pistello, M.2    Lombardi, S.3
  • 5
    • 2342435026 scopus 로고    scopus 로고
    • Transmission and immunopathogenesis of FIV in cats as a model for HIV
    • Burkhard MJ, Dean GA. Transmission and immunopathogenesis of FIV in cats as a model for HIV. Curr HIV Res 2003;1:15-29.
    • (2003) Curr HIV Res , vol.1 , pp. 15-29
    • Burkhard, M.J.1    Dean, G.A.2
  • 6
    • 0031965078 scopus 로고    scopus 로고
    • Mucosally transmitted feline immunodeficiency virus induces a CD8+ antiviral response that correlates with reduction of cell-associated virus
    • Bucci J, English R, Jordan H, et al. Mucosally transmitted feline immunodeficiency virus induces a CD8+ antiviral response that correlates with reduction of cell-associated virus. J Infect Dis 1998;177:18-25.
    • (1998) J Infect Dis , vol.177 , pp. 18-25
    • Bucci, J.1    English, R.2    Jordan, H.3
  • 7
    • 0027472659 scopus 로고
    • Infection with feline immunodeficiency virus is followed by the rapid expansion of a CD8+ lymphocyte subset
    • Willett BJ, Hosie MJ, Callanan JJ, et al. Infection with feline immunodeficiency virus is followed by the rapid expansion of a CD8+ lymphocyte subset. Immunology 1993;78:1-6.
    • (1993) Immunology , vol.78 , pp. 1-6
    • Willett, B.J.1    Hosie, M.J.2    Callanan, J.J.3
  • 8
    • 51849141926 scopus 로고    scopus 로고
    • No major differences in the functional profile of HIV Gag and Nef-specific CD8+ responses between long-term nonprogressors and typical progressors
    • Lopez M, Soriano V, Lozano S, et al. No major differences in the functional profile of HIV Gag and Nef-specific CD8+ responses between long-term nonprogressors and typical progressors. AIDS Res Hum Retroviruses 2008;24:1185-1195.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , pp. 1185-1195
    • Lopez, M.1    Soriano, V.2    Lozano, S.3
  • 9
    • 62749134469 scopus 로고    scopus 로고
    • Comparisons of CD8+ T cells specific for human immunodeficiency virus, hepatitis C virus, and cytomegalovirus reveal differences in frequency, immunodominance, phenotype, and interleukin-2 responsiveness
    • Jagannathan P, Osborne CM, Royce C, et al. Comparisons of CD8+ T cells specific for human immunodeficiency virus, hepatitis C virus, and cytomegalovirus reveal differences in frequency, immunodominance, phenotype, and interleukin-2 responsiveness. J Virol 2009;83:2728-2742.
    • (2009) J Virol , vol.83 , pp. 2728-2742
    • Jagannathan, P.1    Osborne, C.M.2    Royce, C.3
  • 10
    • 29944437982 scopus 로고    scopus 로고
    • Low-dose interferon-alpha treatment for feline immunodeficiency virus infection
    • Pedretti E, Passeri B, Amadori M, et al. Low-dose interferon-alpha treatment for feline immunodeficiency virus infection. Vet Immunol Immunopathol 2006;109:245-254.
    • (2006) Vet Immunol Immunopathol , vol.109 , pp. 245-254
    • Pedretti, E.1    Passeri, B.2    Amadori, M.3
  • 11
    • 44649176876 scopus 로고    scopus 로고
    • American Association of Feline Practitioners' feline retrovirus management guidelines
    • Levy J, Crawford C, Hartmann K, et al. American Association of Feline Practitioners' feline retrovirus management guidelines. J Feline Med Surg 2008;10:300-316.
    • (2008) J Feline Med Surg , vol.10 , pp. 300-316
    • Levy, J.1    Crawford, C.2    Hartmann, K.3
  • 12
    • 0026619819 scopus 로고
    • Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms
    • Hartmann K, Donath A, Beer B., et al. Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms. Vet Immunol Immunopathol 1992;35:167-175.
    • (1992) Vet Immunol Immunopathol , vol.35 , pp. 167-175
    • Hartmann, K.1    Donath, A.2    Beer, B.3
  • 13
    • 0033836047 scopus 로고    scopus 로고
    • Antiviral therapy reduces viral burden but does not prevent thymic involution in young cats infected with feline immunodeficiency virus
    • Hayes KA, Phipps AJ, Francke S, Mathes LE. Antiviral therapy reduces viral burden but does not prevent thymic involution in young cats infected with feline immunodeficiency virus. Antimicrob Agents Chemother 2000;44:2399-2405.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2399-2405
    • Hayes, K.A.1    Phipps, A.J.2    Francke, S.3    Mathes, L.E.4
  • 14
    • 0036212779 scopus 로고    scopus 로고
    • Is AZT/3TC therapy effective against FIV infection or immunopathogenesis?
    • Arai M, Earl DD, Yamamoto JK. Is AZT/3TC therapy effective against FIV infection or immunopathogenesis? Vet Immunol Immunopathol 2002;85:189-204.
    • (2002) Vet Immunol Immunopathol , vol.85 , pp. 189-204
    • Arai, M.1    Earl, D.D.2    Yamamoto, J.K.3
  • 15
    • 84995007808 scopus 로고
    • Long-term treatment of diseased, FIV-seropositive field cats with azidothymidine (AZT)
    • Hart S, Nolte I. Long-term treatment of diseased, FIV-seropositive field cats with azidothymidine (AZT). Zentralbl Veterinarmed A 1995;42:397-409.
    • (1995) Zentralbl Veterinarmed A , vol.42 , pp. 397-409
    • Hart, S.1    Nolte, I.2
  • 16
    • 79955504649 scopus 로고    scopus 로고
    • Antiviral chemotherapy in veterinary medicine
    • Hartmann K. Antiviral chemotherapy in veterinary medicine. Proc ACVIM Forum 2008;26:634-636.
    • (2008) Proc ACVIM Forum , vol.26 , pp. 634-636
    • Hartmann, K.1
  • 17
    • 77957183431 scopus 로고
    • Zidovudine toxicity to cats infected with feline leukemia virus
    • Haschek WM, Weigel RM, Scherba G, et al. Zidovudine toxicity to cats infected with feline leukemia virus. Fundamental Appl Tox 1990;14:764-775.
    • (1990) Fundamental Appl Tox , vol.14 , pp. 764-775
    • Haschek, W.M.1    Weigel, R.M.2    Scherba, G.3
  • 18
    • 0022996630 scopus 로고
    • Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase
    • Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci USA 1986;83:8333-8337.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 8333-8337
    • Furman, P.A.1    Fyfe, J.A.2    St Clair, M.H.3
  • 19
    • 0034162182 scopus 로고    scopus 로고
    • Phase II placebo-controlled trial of fozivudine tidoxil for HIV infection, Pharmacokinetics, tolerability, and efficacy
    • Girard PM, Pegram PS, Diquet B, et al. Phase II placebo-controlled trial of fozivudine tidoxil for HIV infection: Pharmacokinetics, tolerability, and efficacy. J Acquir Immune Defic Syndr 2000;23:227-235.
    • (2000) J Acquir Immune Defic Syndr , vol.23 , pp. 227-235
    • Girard, P.M.1    Pegram, P.S.2    Diquet, B.3
  • 20
    • 0035031308 scopus 로고    scopus 로고
    • Cellular metabolism in lymphocytes of a novel thioether-phospholipid-AZT conjugate with anti-HIV-1 activity
    • Kucera GL, Goff CL, Iyer N, et al. Cellular metabolism in lymphocytes of a novel thioether-phospholipid-AZT conjugate with anti-HIV-1 activity. Antiviral Res 2001;50:129-137.
    • (2001) Antiviral Res , vol.50 , pp. 129-137
    • Kucera, G.L.1    Goff, C.L.2    Iyer, N.3
  • 21
    • 79955517343 scopus 로고    scopus 로고
    • Preliminary tolerance of 28-day oral administration of fozivudine to cats. Study Memorandum-Piedmont Pharmaceuticals. 2007-2008.
    • Pharmaceuticals P. Preliminary tolerance of 28-day oral administration of fozivudine to cats. Study Memorandum-Piedmont Pharmaceuticals. 2007-2008.
    • Pharmaceuticals, P.1
  • 22
    • 0027964486 scopus 로고
    • Development of clinical disease in cats experimentally infected with feline immunodeficiency virus
    • English RV, Nelson P, Johnson CM, et al. Development of clinical disease in cats experimentally infected with feline immunodeficiency virus. J Infec Dis 1994;170:543-552.
    • (1994) J Infec Dis , vol.170 , pp. 543-552
    • English, R.V.1    Nelson, P.2    Johnson, C.M.3
  • 23
    • 0027771388 scopus 로고
    • Feline immunodeficiency virus predisposes cats to acute generalized toxoplasmosis
    • Davidson MG, Rottman J, English RV, et al. Feline immunodeficiency virus predisposes cats to acute generalized toxoplasmosis. Am J Pathol 1993;143:1486-1497.
    • (1993) Am J Pathol , vol.143 , pp. 1486-1497
    • Davidson, M.G.1    Rottman, J.2    English, R.V.3
  • 24
    • 0025604821 scopus 로고
    • Characterization of monoclonal antibodies to feline T lymphocytes and their use in the analysis of lymphocyte tissue distribution in the cat
    • Tompkins MB, Gebhard DH, Bingham HR., et al. Characterization of monoclonal antibodies to feline T lymphocytes and their use in the analysis of lymphocyte tissue distribution in the cat. Vet Immunol Immunopathol 1990;26:305-317.
    • (1990) Vet Immunol Immunopathol , vol.26 , pp. 305-317
    • Tompkins, M.B.1    Gebhard, D.H.2    Bingham, H.R.3
  • 25
    • 56149119408 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells are infected and activated during acute FIV infection
    • Mexas AM, Fogle JE, Tompkins WA, Tompkins MB. CD4+CD25+ regulatory T cells are infected and activated during acute FIV infection. Vet Immunol Immunopathol 2008;126:263-272.
    • (2008) Vet Immunol Immunopathol , vol.126 , pp. 263-272
    • Mexas, A.M.1    Fogle, J.E.2    Tompkins, W.A.3    Tompkins, M.B.4
  • 26
    • 77149164820 scopus 로고    scopus 로고
    • CD4(+)CD25(+) T regulatory cells inhibit CD8(+) IFN-gamma production during acute and chronic FIV infection utilizing a membrane TGF-beta-dependent mechanism
    • Fogle JE, Mexas AM, Tompkins WA, Tompkins MB. CD4(+)CD25(+) T regulatory cells inhibit CD8(+) IFN-gamma production during acute and chronic FIV infection utilizing a membrane TGF-beta-dependent mechanism. AIDS Res Hum Retroviruses 2010;26:201-216.
    • (2010) AIDS Res Hum Retroviruses , vol.26 , pp. 201-216
    • Fogle, J.E.1    Mexas, A.M.2    Tompkins, W.A.3    Tompkins, M.B.4
  • 27
    • 0037378795 scopus 로고    scopus 로고
    • In vivo antiretroviral activity of stampidine in chronically feline immunodeficiency virus-infected cats
    • Uckun FM, Chen CL, Samuel P, et al. In vivo antiretroviral activity of stampidine in chronically feline immunodeficiency virus-infected cats. Antimicrob Agents Chemother 2003;47:1233-1240.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1233-1240
    • Uckun, F.M.1    Chen, C.L.2    Samuel, P.3
  • 28
    • 0027537928 scopus 로고
    • Prophylactic ZDV therapy prevents early viremia and lymphocyte decline but not primary infection in feline immunodeficiency virus-inoculated cats
    • Hayes KA, Lafrado LJ, Erickson JG, et al. Prophylactic ZDV therapy prevents early viremia and lymphocyte decline but not primary infection in feline immunodeficiency virus-inoculated cats. J Acquir Immune Defic Syndr 1993;6:127-134.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 127-134
    • Hayes, K.A.1    Lafrado, L.J.2    Erickson, J.G.3
  • 29
    • 0031282842 scopus 로고    scopus 로고
    • Phase I/II trial with fozivudine tidoxil (BM 21.1290)
    • A 7 day randomized, placebo-controlled dose-escalating trial
    • Bogner JR, Roecken M, Herrmann DB, et al. Phase I/II trial with fozivudine tidoxil (BM 21.1290): A 7 day randomized, placebo-controlled dose-escalating trial. Antivir Ther 1997;2:257-264.
    • (1997) Antivir Ther , vol.2 , pp. 257-264
    • Bogner, J.R.1    Roecken, M.2    Herrmann, D.B.3
  • 31
    • 0027327507 scopus 로고
    • In vivo lymphocyte tropism of feline immunodeficiency virus
    • English RV, Johnson CM, Gebhard DH, Tompkins MB. In vivo lymphocyte tropism of feline immunodeficiency virus. J Virol 1993;67:5175-5186.
    • (1993) J Virol , vol.67 , pp. 5175-5186
    • English, R.V.1    Johnson, C.M.2    Gebhard, D.H.3    Tompkins, M.B.4
  • 32
    • 0030824066 scopus 로고    scopus 로고
    • Toxicity associated with high dosage 9-[(2R,5R-2,5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy off attempts to abort early FIV infection
    • Hartmann K, Ferk G, North TW, Pedersen NC. Toxicity associated with high dosage 9-[(2R, 5R-2, 5-dihydro-5-phosphonomethoxy)-2-furanyl]adenine therapy off attempts to abort early FIV infection. Antiviral Res 1997;36:11-25.
    • (1997) Antiviral Res , vol.36 , pp. 11-25
    • Hartmann, K.1    Ferk, G.2    North, T.W.3    Pedersen, N.C.4
  • 33
    • 17344366517 scopus 로고    scopus 로고
    • BM 21.1290: Pharmacological/toxicological evaluation of a novel candidate anti-AIDS drug
    • Herrmann DBJ, Opitz H-G. BM 21.1290: Pharmacological/toxicological evaluation of a novel candidate anti-AIDS drug. AIDS 1996;1 (Suppl 2):S39.
    • (1996) AIDS , vol.1 , Issue.SUPPL 2
    • Herrmann, D.B.J.1    Opitz, H.-G.2
  • 34
    • 0031451851 scopus 로고    scopus 로고
    • Single dose, dose-escalating trial with fozivudine tidoxil (BM 211290)
    • Bogner JR, Boerner D, Muhlhofer A, et al. Single dose, dose-escalating trial with fozivudine tidoxil (BM 211290). Antivir Ther 1997;2:249-256.
    • (1997) Antivir Ther , vol.2 , pp. 249-256
    • Bogner, J.R.1    Boerner, D.2    Muhlhofer, A.3


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