Bisphosphonate use and risk of post-operative fracture among patients undergoing a total knee replacement for knee osteoarthritis: A propensity score analysis

Osteoporosis International

Volumn 22, Issue 5, 2011, Pages 1555-1571

  Prieto Alhambra, D ^a,b,c,d   Javaid, M K ^a   Judge, A ^a   Maskell, J ^a,e   Kiran, A ^a   Cooper, C ^a,e   Arden, N K ^a,e,f  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b INSTITUT CATALÀ DE LA SALUT   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^d Research Institute University Primary Care IDIAP Jordi Gol   (Spain)

^e UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Arthroplasty; Bone; Diphosphonates; Epidemiology; Fractures; Knee; Propensity score; Replacement

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; RALOXIFENE; RISEDRONIC ACID; STRONTIUM; VITAMIN D;

AGED; ARTICLE; COHORT ANALYSIS; DRUG EXPOSURE; FEMALE; FRACTURE; FRAGILITY FRACTURE; HAZARD RATIO; HIP FRACTURE; HUMAN; HUMERUS FRACTURE; KNEE ARTHROPLASTY; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; POSTOPERATIVE FRACTURE; PRESCRIPTION; PRIORITY JOURNAL; SPINE FRACTURE; WRIST FRACTURE;

AGED; ARTHROPLASTY, REPLACEMENT, KNEE; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; DIPHOSPHONATES; DRUG UTILIZATION; EPIDEMIOLOGIC METHODS; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; OSTEOPOROTIC FRACTURES; SPAIN;

EID: 79955479017     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-010-1368-1     Document Type: Article

References (38)

1. C Cooper G Campion LJ Melton 3rd 1992 Hip fractures in the elderly: a world-wide projection Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2 285 289 1:STN:280: DyaK3s%2Fktlyrtw%3D%3D
2. DT Felson A Naimark J Anderson L Kazis W Castelli RF Meenan 1987 The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study Arthritis Rheum 30 914 918 3632732 10.1002/art.1780300811 1:STN:280:DyaL2szis1GgsQ%3D%3D (Pubitemid 17140857)
3. KM Jordan S Sawyer P Coakley HE Smith C Cooper NK Arden 2004 The use of conventional and complementary treatments for knee osteoarthritis in the community Rheumatology (Oxford, England) 43 381 384 10.1093/rheumatology/keh045 1:STN:280:DC%2BD2c%2FnsVGitg%3D%3D (Pubitemid 38313192)
4. National Joint R (2009) National Joint Registry for England and Wales. 6th Annual Report
5. A Laupacis R Bourne C Rorabeck D Feeny C Wong P Tugwell K Leslie R Bullas 1994 Costs of elective total hip arthroplasty during the first year. Cemented versus noncemented. J Arthroplasty 9 481 487 7807104 10.1016/0883-5403(94)90093- 0 1:STN:280:DyaK2M7gsFyiuw%3D%3D
6. MV Foss PD Byers 1972 Bone density, osteoarthrosis of the hip, and fracture of the upper end of the femur Ann Rheum Dis 31 259 264 5045904 10.1136/ard.31.4.259 1:STN:280:DyaE383jvFSjsQ%3D%3D
7. MC Nevitt NE Lane JC Scott MC Hochberg AR Pressman HK Genant SR Cummings 1995 Radiographic osteoarthritis of the hip and bone mineral density. The Study of Osteoporotic Fractures Research Group Arthritis Rheum 38 907 916 7612040 10.1002/art.1780380706 1:STN:280:DyaK2Mzjs1Crtg%3D%3D
8. MT Hannan JJ Anderson Y Zhang D Levy DT Felson 1993 Bone mineral density and knee osteoarthritis in elderly men and women. The Framingham Study Arthritis Rheum 36 1671 1680 8250986 10.1002/art.1780361205 1:STN:280: DyaK2c%2Fnt1Sitw%3D%3D (Pubitemid 23360006)
9. M Abdin-Mohamed K Jameson EM Dennison C Cooper NK Arden Hertfordshire Cohort Study G 2009 Volumetric bone mineral density of the tibia is not increased in subjects with radiographic knee osteoarthritis Osteoarthritis and cartilage/OARS, Osteoarthritis Research Society 17 174 177 18684648 10.1016/j.joca.2008.06.004 1:STN:280:DC%2BD1M7itlWqsA%3D%3D
10. NK Arden GO Griffiths DJ Hart DV Doyle TD Spector 1996 The association between osteoarthritis and osteoporotic fracture: the Chingford Study Br J Rheumatol 35 1299 1304 9010060 10.1093/rheumatology/35.12.1299 1:STN:280:DyaK2s7mtlahtw%3D%3D
11. AP Bergink M van der Klift A Hofman JA Verhaar JP van Leeuwen AG Uitterlinden HA Pols 2003 Osteoarthritis of the knee is associated with vertebral and nonvertebral fractures in the elderly: the Rotterdam Study Arthritis Rheum 49 648 657 14558050 10.1002/art.11380 (Pubitemid 37296470)
12. NK Arden S Crozier H Smith F Anderson C Edwards H Raphael C Cooper 2006 Knee pain, knee osteoarthritis, and the risk of fracture Arthritis Rheum 55 610 615 16874784 10.1002/art.22088 (Pubitemid 44289882)
13. Prieto-Alhambra D, Javaid M, Maskell J, Judge A, Nevitt M, Cooper C, Arden NK (2010) Changes in Hip Fracture Rate before and after total knee replacement due to Osteoarthritis: a population-based cohort study. Ann Rheum Dis (in press)
14. DM Black DE Thompson DC Bauer K Ensrud T Musliner MC Hochberg MC Nevitt S Suryawanshi SR Cummings 2000 Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group J Clin Endocrinol Metab 85 4118 4124 11095442 10.1210/jc.85.11.4118 1:CAS:528:DC%2BD3cXotlWnurw%3D (Pubitemid 32055362)
15. ST Harris NB Watts HK Genant CD McKeever T Hangartner M Keller CH Chesnut 3rd J Brown EF Eriksen MS Hoseyni DW Axelrod PD Miller 1999 Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group JAMA 282 1344 1352 10527181 10.1001/jama.282.14.1344 1:CAS:528:DyaK1MXmvFansr0%3D (Pubitemid 29483192)
16. B Ettinger DM Black BH Mitlak RK Knickerbocker T Nickelsen HK Genant C Christiansen PD Delmas JR Zanchetta J Stakkestad CC Gluer K Krueger FJ Cohen S Eckert KE Ensrud LV Avioli P Lips SR Cummings 1999 Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators JAMA 282 637 645 10517716 10.1001/jama.282.7.637 1:CAS:528:DyaK1MXlvVKqurg%3D (Pubitemid 29384151)
17. E Seeman 2006 Strontium ranelate: vertebral and non-vertebral fracture risk reduction Curr Opin Rheumatol 18 Suppl 1 S17 S20 16735841 10.1097/01.bor.0000229523.89546.32 (Pubitemid 44289185)
18. TD Spector 2003 Bisphosphonates: potential therapeutic agents for disease modification in osteoarthritis Aging Clin Exp Res 15 413 418 14703007 1:CAS:528:DC%2BD2cXmsVSmtQ%3D%3D (Pubitemid 37509166)
19. CO Bingham 3rd JC Buckland-Wright P Garnero SB Cohen M Dougados S Adami DJ Clauw TD Spector JP Pelletier JP Raynauld V Strand LS Simon JM Meyer GA Cline JF Beary 2006 Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study Arthritis Rheum 54 3494 3507 17075851 10.1002/art.22160 1:CAS:528:DC%2BD28Xht12mtLbP (Pubitemid 44737161)
20. T Walley A Mantgani 1997 The UK General Practice Research Database Lancet 350 1097 1099 10213569 10.1016/S0140-6736(97)04248-7 1:STN:280: DyaK1M3ivVGrsQ%3D%3D (Pubitemid 27437871)
21. JA Kanis O Johnell A Oden H Johansson E McCloskey 2008 FRAX and the assessment of fracture probability in men and women from the UK Osteoporos Int 19 385 397 18292978 10.1007/s00198-007-0543-5 1:STN:280:DC%2BD1c7nvF2ntA%3D%3D
22. Group Whos (2007) Assessment Of Osteoporosis At The Primary Health Care Who Collaborating Centre For Metabolic Bone Diseases level. Of Sheffield 2007 (available On Request From The Who Collaborating Centre Or The Iof) U Kanis JA, Group WHOS (2007) Assessment of osteoporosis at the primary health care level. WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield 2007 (available on request from the WHO Collaborating Centre or the IOF)
23. TP Van Staa L Abenhaim C Cooper B Zhang HG Leufkens 2000 The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results Pharmacoepidemiol Drug Saf 9 359 366 19025840 10.1002/1099-1557(200009/10)9: 5<359::AID-PDS507>3.0.CO;2-E
24. E Brankin M Walker N Lynch T Aspray Y Lis W Cowell 2006 The impact of dosing frequency on compliance and persistence with bisphosphonates among postmenopausal women in the UK: evidence from three databases Curr Med Res Opin 22 1249 1256 16834823 10.1185/030079906X112688 1:CAS:528:DC%2BD28XotlKgtLw%3D (Pubitemid 44085576)
25. PR Rosenbaum DB Rubin 1983 The central role of the propensity score in observational studies for causal effects Biometrika 70 15 10.1093/biomet/70.1.41
26. LE Braitman PR Rosenbaum 2002 Rare outcomes, common treatments: analytic strategies using propensity scores Ann Intern Med 137 693 695 12379071 (Pubitemid 35176104)
27. SL Normand K Sykora P Li M Mamdani PA Rochon GM Anderson 2005 Readers guide to critical appraisal of cohort studies: 3. Analytical strategies to reduce confounding BMJ 330 1021 1023 15860831 10.1136/bmj.330.7498.1021 (Pubitemid 40604289)
28. PC Austin 2009 Some methods of propensity-score matching had superior performance to others: results of an empirical investigation and Monte Carlo simulations Biom J 51 171 184 19197955 10.1002/bimj.200810488
29. A Barratt PC Wyer R Hatala T McGinn AL Dans S Keitz V Moyer GG For 2004 Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat CMAJ 171 353 358 15313996 10.1503/cmaj.1021197 (Pubitemid 39127990)
30. JR Center TV Nguyen D Schneider PN Sambrook JA Eisman 1999 Mortality after all major types of osteoporotic fracture in men and women: an observational study Lancet 353 878 882 10093980 10.1016/S0140-6736(98)09075-8 1:STN:280:DyaK1M7ptFOlug%3D%3D (Pubitemid 29126875)
31. TD Spector PG Conaghan JC Buckland-Wright P Garnero GA Cline JF Beary DJ Valent JM Meyer 2005 Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173] Arthritis Res Ther 7 R625 R633 15899049 10.1186/ar1716 1:CAS:528:DC%2BD2MXkt1equ7Y%3D
32. LD Carbone MC Nevitt K Wildy KD Barrow F Harris D Felson C Peterfy M Visser TB Harris BW Wang SB Kritchevsky A Health S Body Composition 2004 The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis Arthritis Rheum 50 3516 3525 15529367 10.1002/art.20627 (Pubitemid 39488676)
33. JC Buckland-Wright EA Messent CO Bingham 3rd RJ Ward C Tonkin 2007 A 2 yr longitudinal radiographic study examining the effect of a bisphosphonate (risedronate) upon subchondral bone loss in osteoarthritic knee patients Rheumatology (Oxford) 46 257 264 10.1093/rheumatology/kel213 1:CAS:528:DC%2BD2sXhtVyitbo%3D (Pubitemid 46189786)
34. DM Black DE Thompson DC Bauer K Ensrud T Musliner MC Hochberg MC Nevitt S Suryawanshi SR Cummings T Fracture Intervention 2000 Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group J Clin Endocrinol Metab 85 4118 4124 11095442 10.1210/jc.85.11.4118 1:CAS:528:DC%2BD3cXotlWnurw%3D (Pubitemid 32055362)
35. SR Cummings DM Black DE Thompson WB Applegate E Barrett-Connor TA Musliner L Palermo R Prineas SM Rubin JC Scott T Vogt R Wallace AJ Yates AZ LaCroix 1998 Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial JAMA 280 2077 2082 9875874 10.1001/jama.280.24.2077 1:CAS:528: DyaK1MXjsVWruw%3D%3D (Pubitemid 29014065)
36. O Sheehy CM Kindundu M Barbeau J LeLorier 2009 Differences in persistence among different weekly oral bisphosphonate medications Osteoporos Int 20 1369 1376 19020921 10.1007/s00198-008-0795-8 1:CAS:528:DC%2BD1MXotlyhu7w%3D
37. JJ Caro KJ Ishak KF Huybrechts G Raggio C Naujoks 2004 The impact of compliance with osteoporosis therapy on fracture rates in actual practice Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 15 1003 1008 (Pubitemid 40064656)
38. PC Austin 2008 The performance of different propensity-score methods for estimating relative risks J Clin Epidemiol 61 537 545 18471657 10.1016/j.jclinepi.2007.07.011