Comparing micellar, hemolytic, and antibacterial properties of di- and tricarboxyl dendritic amphiphiles

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 9, 2011, Pages 2918-2926

  Maisuria, Bhadreshkumar B ^a,c   Actis, Marcelo L ^a,d   Hardrict, Shauntrece N ^a,e   Falkinham III, Joseph O ^a   Cole, Michael F ^b   Cihlar, Ronald L ^b   Peters, Stephen M ^b   MacRi, Richard V ^a,f   Sugandhi, Eko W ^a,g   Williams, André A ^a   Poppe, Michael A ^a   Esker, Alan R ^a   Gandour, Richard D ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c LUNA INNOVATIONS INC   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e BASF CORPORATION   (United States)

^f WAKE FOREST UNIVERSITY   (United States)

^g US Army Research Labs ^*

Author keywords

Critical micelle concentrations; Dendritic amphiphiles; Hemolytic activities; MRSA; Staphylococcus aureus

Indexed keywords

4 (DOCOSYLOXYCARBONYLAMINO) 4 METHYLHEPTANEDIOIC ACID; 4 (HEXADECYLOXYCARBONYLAMINO) 4 METHYLHEPTANEDIOIC ACID; 4 (ICOSYLOXYCARBONYLAMINO) 4 METHYLHEPTANEDIOIC ACID; 4 METHYL 4 (1 OXODOCOSYLAMINO)HEPTANEDIOIC ACID; 4 METHYL 4 (1 OXOHEXADECYLAMINO)HEPTANEDIOIC ACID; 4 METHYL 4 (1 OXOICOSYLAMINO)HEPTANEDIOIC ACID; 4 METHYL 4 (1 OXOOCTADECYLAMINO)HEPTANEDIOIC ACID; 4 METHYL 4 (1 OXOTETRADECYLAMINO)HEPTANEDIOIC ACID; 4 METHYL 4 (OCTADECYLOXYCARBONYLAMINO)HEPTANEDIOIC ACID; ANTIINFECTIVE AGENT; DI TERT BUTYL 4 (DOCOSYLOXYCARBONYLAMINO) 4 METHYLHEPTANEDIOIC ACID; DI TERT BUTYL 4 (HEXADECYLOXYCARBONYLAMINO) 4 METHYLHEPTANEDIOIC ACID; DI TERT BUTYL 4 (ICOSYLOXYCARBONYLAMINO) 4 METHYLHEPTANEDIOIC ACID; DI TERT BUTYL 4 AMINO 4 METHYLHEPTANEDIOIC ACID; DI TERT BUTYL 4 ISOCYANATO 4 METHYLHEPTANEDIOIC ACID; DI TERT BUTYL 4 METHYL 4 (1 OXODOCOSYLAMINO)HEPTANEDIOIC ACID; DI TERT BUTYL 4 METHYL 4 (1 OXOHEXADECYLAMINO)HEPTANEDIOIC ACID; DI TERT BUTYL 4 METHYL 4 (1 OXOICOSYLAMINO)HEPTANEDIOIC ACID; DI TERT BUTYL 4 METHYL 4 (1 OXOOCTADECYLAMINO)HEPTANEDIOIC ACID; DI TERT BUTYL 4 METHYL 4 (1 OXOTETRADECYLAMINO)HEPTANEDIOIC ACID; DI TERT BUTYL 4 METHYL 4 (OCTADECYLOXYCARBONYLAMINO)HEPTANEDIOIC ACID; DI TERT BUTYL 4 METHYL 4 NITROHEPTANEDIOIC ACID; HEMOLYTIC AGENT; TRICARBOXYLIC DENDRITIC AMPHIPHILE DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BROTH DILUTION; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; CULTURE MEDIUM; DRUG STRUCTURE; DRUG SYNTHESIS; HEMOLYSIS; HYDROPHILICITY; INOCULATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICELLE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; QUALITY CONTROL; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; DENDRIMERS; HEMOLYSIS; HEPTANOIC ACIDS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICELLES; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCUS AUREUS;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 79955465850     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.03.036     Document Type: Article

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