Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A)

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 9, 2011, Pages 2736-2739

  Van Veldhoven, J P D ^a   Blad, C C ^a   Artsen, C M ^a   Klopman, C ^a   Wolfram, D R ^a   Abdelkadir, M J ^a   Lane, J R ^a   Brussee, J ^a   Ijzerman, A P ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cinnamic acid; Fumaric acid; G protein coupled receptor; GPR109A; Nicotinic acid

Indexed keywords

ACRYLIC ACID; AMIDE; CINNAMIC ACID DERIVATIVE; ESTER; FUMARIC ACID; FUMARIC ACID AMIDE DERIVATIVE; FUMARIC ACID ESTER DERIVATIVE; G PROTEIN COUPLED RECEPTOR; HYDROXYCARBOXYLIC ACID RECEPTOR HCA2; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DRUG SYNTHESIS; MOLECULAR MODEL; PHARMACOPHORE; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ACRYLATES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79955464454     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.11.091     Document Type: Conference Paper

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