Diabetes mellitus alters the mechanical properties of the native tendon in an experimental rat model

Journal of Orthopaedic Research

Volumn 29, Issue 6, 2011, Pages 880-885

  Fox, Alice J S ^a   Bedi, Asheesh ^a   Deng, Xiang Hua ^a   Ying, Liang ^a   Harris, Paul E ^b   Warren, Russell F ^a   Rodeo, Scott A ^a  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

diabetes; mechanical properties; patellar tendon; rat; streptozotocin

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GLYCEMIC CONTROL; HEMOGLOBIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; MALE; MORPHOMETRICS; NONHUMAN; PATELLA; PATELLA TENDON; PHENOTYPE; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; TIBIA; YOUNG MODULUS;

ANIMALS; BIOMECHANICS; DIABETES MELLITUS, EXPERIMENTAL; MALE; PATELLAR LIGAMENT; PHENOTYPE; RATS; RATS, INBRED LEW;

EID: 79955464201     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21327     Document Type: Article

References (49)

1. Macey LR, Kana SM, Jinushi S, et al. 1989. Defects of early fracture-healing in experimental diabetes. JBJS 71: 722-733. (Pubitemid 19179662)
2. Loder RT,. 1988. The influence of diabetes mellitus on the healing of closed fractures. Clin Orthop 232: 210-216.
3. Cozen L,. 1972. Does diabetes delay fracture healing? Clin Orthop 82: 134-140.
4. Wray JB, Stunkle E,. 1965. The effect of experimental diabetes on the breaking strength of the healing fracture in the rat. J Surg Res 5: 479-481.
5. Herbsman H, Powers JC, Hirschman A, et al. 1968. Retardation of fracture healing in experimental diabetes. J Surg Res 8: 424-431.
6. Funk JR, Hale JE, Carmines D, et al. 2000. Biomechanical evaluation of early fracture healing in normal and diabetic rats. J Orthop Res 18: 126-132.
7. Saha MT, Sievänen H, Salo MK, et al. 2009. Bone mass and structure in adolescents with type 1 diabetes compared to healthy peers. Osteoporos Int 20: 1401-1406.
8. Heilman K, Zilmer M, Zilkmer K, et al. 2009. Lower bone mineral density in children with type 1 diabetes is associated with poor glycemic control and higher serum ICAM-1 and urinary isoprostane levels. J Bone Miner Metab 27: 598-604.
9. Spanheimer RG,. 1992. Correlation between decreased collagen production in diabetic animals and in cells exposed to diabetic serum: response to insulin. Matrix 12: 101-107.
10. Leung MK, Folkes GA, Ramamurthy NS, et al. 1986. Diabetes stimulates procollagen degradation on rat tendon in vitro. Biochim Biophys Acta 880: 147-152. (Pubitemid 16051026)
11. Arkkila PE, Kantola IM, Viikari JS, et al. 1996. Shoulder capsulitis in type I and II diabetic patients: association with diabetic complications and related diseases. Ann Rheum Dis 55: 907-914. (Pubitemid 26426685)
12. Balci N, Balci MK, Tuzuner S,. 1999. Shoulder adhesive capsulitis and shoulder range of motion in type II diabetes: association with diabetic complications. J Diab Comp 13: 135-140. (Pubitemid 29430213)
13. Bridgman JF,. 1972. Periarthritis of the shoulder and diabetes mellitus. Ann Rheum Dis 31: 69-71.
14. Rao SR, Saltzman CL, Wilken J, et al. 2006. Increased passive ankle stiffness and reduced dorsiflexion range of motion in individuals with diabetes mellitus. Foot Ankle Int 27: 617-622. (Pubitemid 44289939)
15. Trevino SG, Buford WL, Nakamura T, et al. 2004. Use of a torque-range-of-motion device for objective differentiation of diabetic from normal feet in adults. Foot Ankle Int 25: 561-567. (Pubitemid 39096105)
16. Batista F, Nery C, Pinzur M, et al. 2008. Achilles tendinopathy in diabetes mellitus. Foot Ankle Int 29: 498-501. (Pubitemid 351619974)
17. James VJ, Delbridge L, McLennan SV, et al. 1991. Use of X-ray diffraction in study of human diabetic and aging collagen. Diabetes 40: 391-394.
18. Reddy GK, Stehno-Bittel L, Enwemeka CS,. 2002. Glycation-induced matrix stability in the rat Achilles tendon. Arch Biochem Biophys 399: 174-180. (Pubitemid 34848604)
19. Sell DR, Monnier VM,. 1990. End-stage renal disease and diabetes catalyze the formation of a pentose-derived crosslink from aging human collagen. J Clin Invest 85: 380-384. (Pubitemid 20070042)
20. Degroot J, Verzijl N, Budde M, et al. 2001. Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes. Exp Cell Res 266: 303-310. (Pubitemid 32579235)
21. Grant WP, Sullivan R, Sonenshine DE, et al. 1997. Electron microscopic investigation of the effect of diabetes mellitus on the Achilles tendon. J Foot Ankle Surg 36: 272-278. (Pubitemid 27387874)
22. Odetti P, Aragno I, Rolandi R, et al. 2000. Scanning force microscopy reveals structural alterations in diabetic rat collagen fibrils: role of protein glycation. Diab Metab Res Rev 16: 74-81. (Pubitemid 30219042)
23. Chen AL, Shapiro JA, Ahn AK, et al. 2003. Rotator cuff repair in patients with type 1 diabetes mellitus. J Shoulder Elbow Surg 12: 416-421. (Pubitemid 37237510)
24. Saxena A, Maffulli N, Nguyen A, et al. 2008. Wound complications from surgeries pertaining to the Achilles tendon. J Am Podiatr Med Assoc 98: 95-101.
25. Ramirez LC, Raskin P,. 1998. Diabetic foot tendinopathy: abnormalities in the flexor plantar tendons in patients with diabetes mellitus. J Diabetes Compl 12: 337-339. (Pubitemid 29029888)
26. Cook JL, Khan KM, Kiss ZS, et al. 2000. Patellar tendinopathy in junior basketball players: a controlled clinical and ultrsonographic study of 268 patellar tendons in players aged 14-18 years. Scand J Med Sci Sports 10: 216-220.
27. Maffulli N, Wong J, Almekinders LC,. 2003. Types and epidemiology of tendons. Clin Sports Med 22: 675-692.
28. Maffulli N, Testa V, Capasso G, et al. 2006. Surgery for chronic Achilles tendinopathy yields worse results in nonathletic patients. Clin J Sport Med 16: 123-128. (Pubitemid 43670373)
29. Rahbar S, Blumenfeld O, Ranney HM,. 1969. Studies of an unusual hemoglobin in patients with diabetes mellitus. Biochem Biophys Res Commun 36: 838-843.
30. Gabbay KH, Hasty K, Breslow JL, et al. 1977. Glycosylated hemoglobins and long-term blood glucose control in diabetes mellitus. J Clin Endocrinol Metab 44: 859-864. (Pubitemid 8104630)
31. Bunn HF, Shapiro R, McManus M, et al. 1979. Structural heterogeneity of human hemoglobin A due to nonenzymatic glycosylation. J Biol Chem 254: 3892-3898. (Pubitemid 9178801)
32. Koenig RJ, Peterson CM, Kilo C, et al. 1976. Hemoglobin A1c as an indicator of the degree of glucose intolerance in diabetes. Diabetes 25: 20-232.
33. Yue DK, McLennan S, Church DB, et al. 1982. The measurement of glycosylated haemoglobin in man and animals by aminophenylboronic acid affinity chromatography. Diabetes 31: 701-705. (Pubitemid 12095167)
34. Gulotta LV, Kovacevic D, Ehteshami JR, et al. 2009. Application of bone-marrow derived mesenchymal stem cells in a rotator cuff repair model. Am J Sports Med 37: 2126-2133.
35. Bedi A, Kovacevic D, Hettrich C, et al. 2010. The effect of matrix metalloproteinase inhibition on tendon-bone healing in a rotator cuff repair model. J Shoulder Elbow Surg 19: 384-391.
36. Chbinou N, Frenette J,. 2004. Insulin-dependent diabetes impairs the inflammatory response and delays angiogenesis following Achilles tendon injury. Am J Physiol Regul Comp Physiol 286: R952-R957. (Pubitemid 38506843)
37. Darby IA, Bisucc T, Hewitson TD, et al. 1997. Apoptosis is increased in a model of diabetes-impaired wound healing in genetically diabetic mice. Int J Biochem Cell Biol 29: 191-200. (Pubitemid 27096432)
38. Loots M, Lamme EN, Mekkes JR, et al. 1999. Cultured fibroblasts from chronic diabetic wounds on the lower extremity (non-insulin-dependent diabetes mellitus) show disturbed proliferation. Arch Dermatol Res 291: 93-99. (Pubitemid 29116523)
39. Maffulli N, Sharma P, Luscombe KL,. 2004. Achilles tendinopathy: aetiology and management. J R Soc Med 97: 472-476. (Pubitemid 39424603)
40. Magra M, Maffulli N,. 2005. Matrix metalloproteases: a role in overuse tendinopathies. Br J Sports Med 39: 789-791. (Pubitemid 41564911)
41. Woo SLY, Ritter MA, Amiel D, et al. 1980. The biomechanical and biochemical properties of swine tendons - long term effects of exercise on the digital extensors. Connect Tissue Res 7: 177-183. (Pubitemid 10063459)
42. Simonsen EB, Klitgaard H, Bojsen-Moller F,. 1995. The influence of strength training, swim training and ageing on the Achilles tendon and M. soleus of the rat. J Sports Sci 13: 291-295.
43. Viidik S,. 1969. Tensile strength properties of Achilles tendon systems in trained and untrained rabbits. Acta Orthop Scand 40: 261-272.
44. Andreassen TT, Seyer-Hansen K, Bailey AJ,. 1981. Thermal stability, mechanical properties and reducible cross-links of rat tail tendon in experimental diabetes. Biochim Biophys 677: 313-317. (Pubitemid 12239109)
45. Altinel L, Cagri Kose K, Degirmenci B, et al. 2007. The midterm effect of diabetes mellitus on quadriceps and patellar tendons in patients with knee arthrosis: a comparative radiologic study. J Diabetes Complications 21: 392-396. (Pubitemid 47633237)
46. Gaida JE, Ashe MC, Bass SL, et al. 2009. Is adiposity an under-recognized risk factor for tendinopathy? A systemic review. Arthritis Care Res 61: 840-849.
47. Scott JE,. 1988. Proteoglycan-fibrillar collagen interactions. Biochem J 252: 313-323.
48. Corps AN, Jones GC, Harrall RL, et al. 2008. The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells. Matrix Biol 27: 393-401.
49. Yue DK, Swanson B, McLennan S, et al. 1986. Abnormalities of granulation tissue and collagen formation in experimental diabetes, uraemia and malnutrition. Diabetic Med 3: 221-225. (Pubitemid 16068492)