Correlation of EPHX1, GSTP1, GSTM1, and GSTT1 genetic polymorphisms with antioxidative stress markers in chronic obstructive pulmonary disease

Experimental Lung Research

Volumn 37, Issue 4, 2011, Pages 195-204

  Lakhdar, Ramzi ^a   Denden, Sabri ^a   Mouhamed, Manel Haj ^b   Chalgoum, Abdelkader ^b   Leban, Nadia ^a   Knani, Jalel ^c   Lefranc, Gérard ^d   Miled, Abelhadi ^b   Chibani, Jemni Ben ^a   Khelil, Amel Haj ^a  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b FARHAT HACHED HOSPITAL   (Tunisia)

^c CHU Tahar Sfar   (Tunisia)

^d INSTITUTE OF HUMAN GENETICS   (France)

Author keywords

COPD; genetic polymorphism; glutathione S transferase; microsomal epoxide hydrolase; oxidative stress

Indexed keywords

BIOLOGICAL MARKER; CATALASE; EPOXIDE HYDROLASE; EPOXIDE HYDROLASE X1; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROL GROUP; CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; EXON; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INFORMATION PROCESSING; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; REDOX STRESS; TUNISIA;

BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; EPOXIDE HYDROLASES; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; OXIDATION-REDUCTION; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 79955446941     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.3109/01902148.2010.535093     Document Type: Article

References (48)

1. Pauwels RA, Rabe KF: Burden and clinical features of chronic obstructive pulmonary disease (COPD). Lancet. 2004;364:613-620. (Pubitemid 39094180)
2. Mayer AS, Newman LS: Genetic and environmental modulation of chronic obstructive pulmonary disease. Respir Physiol. 2001;128:3-11. (Pubitemid 32771686)
3. Barnes PJ, Shapiro SD, Pauwels RA: Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J. 2003;22:672-688. (Pubitemid 37258549)
4. Demedts IK, Brusselle GG, Bracke KR, Vermaelen KY, Pauwels RA: Matrix metalloproteinases in asthma and COPD. Curr Opin Pharmacol. 2005;5:257-263. (Pubitemid 40674248)
5. Hoffmann D, Hoffmann I: The changing cigarette, 1950-1995. J Toxicol Environ Health. 1997;50:307-364.
6. Molfno NA: Genetics of COPD. Chest. 2004;125:1929-1940.
7. Joos L, He JQ, Shepherdson MB, et al.: The role of matrix metalloproteinase polymorphisms inthe rate ofdecline in lungfunction. Hum Mol Genet. 2002;11:5679-5676.
8. Vibhuti A, Arif E, Deepak D, Singh B, Pasha MA: Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD. Biochem Biophys Res Comm. 2007;359:136-142. (Pubitemid 46836679)
9. Nebert DW, Vasiliou V: Analysis ofthe glutathione 5-transferase (GST) gene family. Hum Genomics. 2004;1:460-464.
10. Strange RC, Spiteri MA, Ramachandran S, Fryer AA: Glutathione 5-transferase family of enzymes. Mutat Res. 2001;482:21-26.
11. Seidegard J, Ekstrom G: The role ofhuman glutathione transferases and epoxide hydrolases in the metabolism ofxenobiotics. Environ Health Perspect. 1997;105:791-799. (Pubitemid 27372964)
12. Eaton DL, Bammler TK: Concise review of the glutathione 5-transferase and their signifcance to toxicology. Toxicol Sci. 1999;49:156-164. (Pubitemid 29300401)
13. Cantlay AM, Smith CAD, Wallace WA, Yap PL, Lamb D, Harrison DJ: Heterogeneous expression and polymorphic genotype of glutathione 5-transferase in human lung. Thorax. 1994;49:1010-1014. (Pubitemid 24315995)
14. Pemble S, Schroeder KR, Spencer SR, et al.: Human glutathione 5-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem J 1994;300:271-276. (Pubitemid 24151046)
15. Zimniak P, Nandur B, Pikula S, et al.: Naturally occurring human glutathione 5-transferase GSTP-1 isoforms with isoleucine and valine in position 104 differ in enzymatic properties. Eur J Biochem. 1994;224:893-899. (Pubitemid 24288851)
16. Hassett C, Aicher L, Sidhu JS, et al.: Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet. 1994;3:421-428. (Pubitemid 24083901)
17. Rahman I, Macnee W: Oxidant/antioxidant imbalance in smokers and chronic obstructive pulmonary disease. Thorax. 1996;51:348-350. (Pubitemid 26140195)
18. Santos MC, Oliveira AL, Viegas-Crespo AM, et al.: Systemic markers of the redox balance in chronic obstructive pulmonary disease. Biomarkers 2004;9:461-469. (Pubitemid 40403129)
19. Paglia DE, Valentine WN: Studies on the quantitative and qualitative characterisation of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967;70:158-169.
20. McCord JM, Fridovich I: Superoxide dismutase. An enzymatic function for erythrocuprein (hemocuprein). J Biol Chem. 1969;244:6049-6055.
21. Rice-Evans C, Miller NJ: Total antioxidant status in plasma and bodyfuids. Methods Enzymol. 1994;234:279-293.
22. Aebi H: Catalase. In: Bergmeyer HU, ed. Methods in Enzymatic Analysis. Vol. 2. New York: Academic Press; 1974:673-678.
23. Habig WH, Pabst MJ, Jakoby WB: Glutathione 5-transferases: the frst enzymatic step in mercapturic acid formation. J Biol Chem. 1974;249:7130-7139.
24. Lakhdar R, Denden S, Knani J, et al.: Association between GSTM1 and GSTT1 polymorphisms with COPD in Tunisian population. Biochem Genet. 2010;48:647-657.
25. Lakhdar R, Denden S, Knani J, et al.: Relationship between glutathione 5-transferase P1 polymorphisms and chronic obstructive pulmonary disease in Tunisian population. Genet Mol Res. 2010;9:897-907.
26. Lakhdar R, Denden S, Knani J, et al.: Microsomal epoxide hydrolase gene (EPHX1) polymorphisms and susceptibility to chronic obstructive pulmonary disease in Tunisian population. Genet Test Mol Biomarkers. DOI: 10.1089/gtmb.2009. 0168.
27. MacNee W: Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2005;2:50-60. (Pubitemid 40562963)
28. Nadeem A, Raj HG, Chhabra SK: Increased oxidative stress and altered levels of antioxidants in chronic obstructive pulmonary disease. Infammation. 2005;29:23-32.
29. Pryor WA, Srone K: Oxidant in cigarette smoke: radicals, hydrogen peroxides, peroxynitrate. Ann N Y Acad Sci. 1993;686:121-128.
30. Macnee W, Rahman I: Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999;60:558-565.
31. Church T, Pryor WA: Free-radical chemistry ofcigarette smoke and its toxicological implications. Environ Health Perspect. 1981;64:111-126. (Pubitemid 16135783)
32. Bowers R, Cool C, Murphy RC, et al.: Oxidative stress in severe pulmonary hypertension. Am J Respir Crit Care Med. 2004;169:764-769. (Pubitemid 38338929)
33. Blum J, Fridovich I: Inactivation of glutathione peroxidase by superoxide radical. Arch Biochem Biophys. 1985;249:500-508. (Pubitemid 15250062)
34. Daga MK, Chhabra R, Sharma B, Mishra TK: Effects of exogenous vitamin E supplementation on the levels of oxidants and antioxidants in chronic obstructive pulmonary disease. J Biosci. 2003;28:7-11. (Pubitemid 36268240)
35. Kondo T, Tagami S, Yoshioka A, Nishimura M, Kawakami Y: Current smoking of elderly men reduces antioxidants in alveolar macrophages.Am J Respir Crit Care Med. 1994;149:178-182. (Pubitemid 24066117)
36. Wu G, Fang YZ, Yang S, Lupton JR, Turner ND: Glutathione metabolism and its implications for health. J Nutr. 2004;134:489-492. (Pubitemid 38298485)
37. Kocyigit A, Erel O, Gur S: Effects of tobacco smoking on plasma selenium, zinc, copper and iron concentrations and related antioxidant enzyme activities. Clin Biochem. 2001;34:629-633. (Pubitemid 34159353)
38. Hanta I, Kocabas A, Canacankatan N, Kuleci S, Seydaoglu G: Oxidant-antioxidant balance in patients with COPD. Lung. 2006;184:51-55.
39. Sadowska AM, Luyten C, Vints AM, Verbraecken J, Ranst DV, De Backer WA: Systemic antioxidant defences during acute ex-acerbation of chronic obstructive pulmonary disease. Respirology. 2006;11:741-747. (Pubitemid 44581438)
40. Mak JC, Ho SP, Yu WC, et al.: Polymorphisms and functional activity in superoxide dismutase and catalase genes in smokers with COPD. Eur Respir J. 2007;30:684-690. (Pubitemid 351194828)
41. Gumral N, Naziroglu M, Ongel K, et al.: Antioxidant enzymes and melatonin levels in patients with bronchial asthma and chronic obstructive pulmonary disease during stable and exac-erbation periods. Cell Biochem Funct. 2009;27:276-83.
42. Mak JCW, Ho SP, Leung HCM, et al.: Relationship between glutathione 5-transferase gene polymorphisms and enzyme ac-tivity in Hong Kong Chinese asthmatics. Clin Exp Allergy. 2007;37:1150-1157. (Pubitemid 47076339)
43. Chan-Yeung M, Ho SP, Cheung AHK, et al.: Polymorphisms of glutathione 5-transferase genes and functional activity in smokers with or without COPD. Int J Tuberc Lung Dis. 2007;11:508-514. (Pubitemid 46732636)
44. Rahman I, Swarska E, Henry M, Stolk J, MacNee W: Is there any relationship between plasma antioxidant capacity and lung function in smokers and in patients with chronic obstructive pul-monary disease? Thorax. 2000;55:189-193. (Pubitemid 30245967)
45. Nowak D, Kasielski M, Antczak A, et al.: Increased content of thiobarbituric acid-reactive substances and hydrogen peroxide in the expired breath condensate of patients with stable chronic obstructive pulmonary disease: no signifcant effect of cigarette smoking. Respir Med. 1999;93:389-396. (Pubitemid 29265348)
46. Ishii T, Matsuse T, Teramoto S, et al.: Glutathione 5-transferase P1 (GSTP1) polymorphism in patients with chronic obstructive pulmonary disease. Thorax. 1999;54:693-696. (Pubitemid 29341405)
47. Smith CA, Harrison DJ: Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to em-physema. Lancet. 1997;350:630-633. (Pubitemid 27367797)
48. Vibhuti A, Arif E, Mishra A, et al.: CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD. Clin Chim Acta. 2010;411:474-480.