Detection of differential proteomes associated with the development of type 2 diabetes in the Zucker rat model using the iTRAQ technique

Journal of Proteome Research

Volumn 10, Issue 2, 2011, Pages 564-577

  Han, Dohyun ^a   Moon, Sungyoon ^a   Kim, Hyunsoo ^a   Choi, Sung E ^b   Lee, Soo Jin ^b   Park, Kyong Soo ^a   Jun, Heesook ^c   Kang, Yup ^b   Kim, Youngsoo ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c Gachon University College of Medicine   (South Korea)

Author keywords

Beta cell; iTRAQ; Obesity; Type 2 diabetes; Zucker rat model

Indexed keywords

ELASTASE; FIBRILLIN 1; GALECTIN 1; INSULIN; PEPTIDE HYDROLASE; PROTEOME; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RAB PROTEIN; SCLEROPROTEIN; SECRETOGRANIN II; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; GLUCOSE INTOLERANCE; MALE; MICROVASCULAR ISCHEMIA; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; ZUCKER DIABETIC FATTY RAT;

ANIMALS; BLOTTING, WESTERN; CLUSTER ANALYSIS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; ISLETS OF LANGERHANS; ISOTOPE LABELING; MALE; OBESITY; PROTEOME; RATS; RATS, ZUCKER; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 79955427809     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr100759a     Document Type: Article

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