Editorial Commentary: Is it time to abandon progesterone supplementation of early pregnancy after IVF?

Human Reproduction

Volumn 26, Issue 5, 2011, Pages 1017-1019

  Griesinger, Georg ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN AGONIST; PROGESTERONE;

BLEEDING; EDITORIAL; ENDOMETRIOSIS; FERTILIZATION IN VITRO; FIRST TRIMESTER PREGNANCY; HUMAN; OVARY POLYCYSTIC DISEASE; PREGNANCY TEST; SUPPLEMENTATION;

EID: 79955377311     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der013     Document Type: Editorial

References (9)

1. EMEA Committee for Medicinal Products for Human Use (CHMP) 2006. Guideline on the Choice of the Non-Inferiority Margin. Doc. Ref. EMEA/CPMP/EWP/2158/99.
2. International Committee for Monitoring Assisted Reproductive Technology (ICMART), de Mouzon J, Lancaster P, Nygren KG, Sullivan E, Zegers-Hochschild F, Mansour R, Ishihara O, Adamson D. World collaborative report on Assisted Reproductive Technology, 2002. Hum Reprod 2009; 24: 2310-2320.
3. Kyrou D, Fatemi HM, Zepiridis L, Riva A, Papanikolaou EG, Tarlatzis BC, Devroey P. Is cessation of progesterone supplementation during early pregnancy in patients treated with recFSH/GnRH antagonist non-inferior to its continuation regarding pregnancy outcomes? A randomized controlled trial. Hum Reprod 2011, in press.
4. Nyboe-Andersen A, Popovic-Todorovic B, Schmidt KT, Loft A, Lindhard A, Højgaard A, Ziebe S, Hald F, Hauge B, Toft B. Progesterone supplementation during early gestations after IVF or ICSI has no effect on the delivery rates: a randomized controlled trial. Hum Reprod 2002; 17:357-361. (Pubitemid 34168441)
5. Prietl G, Diedrich K, Van der Ven H, Luckhaus J, Krebs D. The effectof 17a-hydroxyprogesterone caproate/oestradiol valerate on the development and outcome of early pregnancies following in vitro fertilization and embryo transfer: a prospective and randomized controlled trial. Hum Reprod 1992;7(Suppl. 1):1-5.
6. Proctor A, Hurst BS, Marshburn PB, Matthews ML. Effect of progesterone supplementation in early pregnancy on the pregnancy outcome after in vitro fertilization. Fertil Steril 2006;85:1550-1552.
7. Schmidt KLT, Ziebe S, Popovic B, Lindhard A, Loft A, Andersen AN. Progesterone supplementation during early gestation after in vitro fertilization has no effect on the delivery rate. Fertil Steril 2001; 75:337-341. (Pubitemid 32112111)
8. Stelling JR, Barrett CB, Penzias AS, Alper MM, Berger MJ, Oskowitz SP, Karnis MF, Gray MR, Reindollar RH. Progesterone Support in Early IVF/GIFT Pregnancies May Not Be Necessary [abstract]. Fertil Steril 1999;(suppl.):S37 (abstr. # O-095).
9. Stovall D, Van Voorhis B, Sparks A, Adams L, Syrop C. Selective early elimination of luteal support in assisted reproduction cycles using a gonadotropin-releasing hormone agonist during ovarian stimulation. Fertil Steril 1998;70:1056-1062. (Pubitemid 28546231)