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Volumn 13, Issue 8, 2011, Pages 1984-1987

Palladium-Catalyzed C,N-Cross coupling reactions of 3-Halo-2-aminopyridines

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPYRIDINE DERIVATIVE; CARBON; CROSS LINKING REAGENT; LIGAND; NITROGEN; PALLADIUM;

EID: 79955371564     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol200371n     Document Type: Article
Times cited : (24)

References (41)
  • 10
    • 79955402532 scopus 로고    scopus 로고
    • Exception: For an SNAr on 3-bromo-2-amino-5-phenylpyridine under harsh reaction conditions
    • Exception: For an SNAr on 3-bromo-2-amino-5-phenylpyridine under harsh reaction conditions.
  • 13
    • 77952986439 scopus 로고    scopus 로고
    • Additionally, the synthesis of 3-butylamino-2-amino-pyridine via nucleophilic substitution has been reported
    • Additionally, the synthesis of 3-butylamino-2-amino-pyridine via nucleophilic substitution has been reported: Liu, Y.; Zhang, W.; Sayre, L. M J. Heterocycl. Chem. 2010, 47, 683.
    • (2010) J. Heterocycl. Chem. , vol.47 , pp. 683
    • Liu, Y.1    Zhang, W.2    Sayre, L.M.3
  • 20
    • 79955451877 scopus 로고    scopus 로고
    • Palladacycles based upon biarylmonophosphines are operationally simple to handle precatalysts which are, easily acivated and ensure formation of the catalytically active monoligated Pd(0 species
    • Palladacycles based upon biarylmonophosphines are operationally simple to handle precatalysts which are, easily acivated and ensure formation of the catalytically active monoligated Pd(0 species.
  • 29
    • 79955392629 scopus 로고    scopus 로고
    • No product formation was observed without ligand or without palladium source under the reaction conditions
    • No product formation was observed without ligand or without palladium source under the reaction conditions.
  • 30
    • 79955427653 scopus 로고    scopus 로고
    • For the role of LiHMDS as a base to enable Pd-catalyzed C,Ncross coupling reactions in the presence of functional groups with acidic protons
    • For the role of LiHMDS as a base to enable Pd-catalyzed C,Ncross coupling reactions in the presence of functional groups with acidic protons
  • 33
    • 79955429320 scopus 로고    scopus 로고
    • Product configuration was confirmed by NOE experiment
    • Product configuration was confirmed by NOE experiment.
  • 34
    • 79955428156 scopus 로고    scopus 로고
    • The prefered C,N-cross coupling in position 3 is in accordance with selectivities observed in C,C-cross coupling reactions
    • The prefered C,N-cross coupling in position 3 is in accordance with selectivities observed in C,C-cross coupling reactions
  • 37
    • 79955419012 scopus 로고    scopus 로고
    • For the origin of regioselectivity in Pd-catalyzed cross-coupling reactions of polyhalogenated heterocycles
    • For the origin of regioselectivity in Pd-catalyzed cross-coupling reactions of polyhalogenated heterocycles.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.