Quantitative in vivo lifetime imaging using a time-domain platform with a supercontinuum tunable laser for extended spectral coverage

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7910, Issue , 2011, Pages

  Mincu, Niculae ^a   Huang, Dao Chao ^a   Piche, Marilyse ^a   Ma, Guobin ^a  

^a ART Advanced Research Technologies Inc   (Canada)

Author keywords

Fluorescence lifetime; Fluorescent methods and biomarkers; Fluorescent nanoprobes; In vivo lifetime imaging; Small animals imaging; Supercontinuum laser; Time resolved spectroscopy

Indexed keywords

FLUORESCENCE LIFETIMES; FLUORESCENT METHODS; FLUORESCENT NANOPROBES; IN-VIVO; SMALL ANIMALS IMAGING; SUPERCONTINUUM LASER; TIME-RESOLVED SPECTROSCOPY;

ANALYTIC EQUIPMENT; ANIMALS; FLUORESCENCE; LASER SPECTROSCOPY; LASERS; NANOPARTICLES; NANOPROBES; PROBES; SILICA; TIME DOMAIN ANALYSIS;

PULSED LASERS;

EID: 79955136027     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.875214     Document Type: Conference Paper

References (7)

1. http://edrn.nci.nih.gov/biomarkers.
2. http://www.biocompare.com/ProductCategories/2605/Probes-And-Dyes.html.
3. Cho, M., Cho, W. S., Choi, M., Kim, S. J., Han, B. S., Kim, S. H., Kim, H. O., Sheen, Y. Y., Jeong, J., "The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles", Toxicol. Lett., 189(3), 177-83(2009).
4. Hall, D., Ma, G., Lesage, F., and Wang, Y., "Simple time domain optical method for estimating the depth and concentration of a fluorescent inclusion in a turbid medium", Opt. Lett., 29, 2258-60 (2004).
5. Ma, G., Fortier, S., Jean-Jacques, M., Mincu, N., Leblond, F., Ichalalene, Z., Benyamin-Seeyar, A., Khayat, M., "Fluorescence lifetime estimation of multiple near-infrared dyes in mice", SPIE Photonics West, BIOS 2008 Biomedical Optics (San Jose, California), January 19-24, 2008. Paper in Multimodal Biomedical Imaging III, edited by Fred S. Azar, Xavier Intes, Proceedings of SPIE Vol. 6850 (SPIE, Bellingham, WA 2008) 685003.
6. Shaner, N. C., Campbell, R. E., Steinbach, P. A., Giepmans, B. N., Palmer, A. E., Tsien R. Y., "Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. Red fluorescent protein", Nat. Biotechnol. 22(4), 1567-72 (2004);. (Pubitemid 40039460)
7. Shaner, N. C., Lin, M. Z., McKeown, M. R., Steinbach, P. A., Hazelwood, K. L., Davidson, M. W., Tsien, R. Y., "Improving the photostability of bright monomeric orange and red fluorescent proteins", Nat. Methods 5(6), 472-3 (2008).