-
1
-
-
77949851963
-
Psychophysical evaluation of a sanshool derivative (alkylamide) and the elucidation of mechanisms subserving tingle
-
Albin KC, Simons CT. Psychophysical evaluation of a sanshool derivative (alkylamide) and the elucidation of mechanisms subserving tingle. PLos One 5: e9520, 2010.
-
(2010)
PLos One
, vol.5
-
-
Albin, K.C.1
Simons, C.T.2
-
2
-
-
1842475312
-
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
-
Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, Patapoutian A. Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41: 849-857, 2004.
-
(2004)
Neuron
, vol.41
, pp. 849-857
-
-
Bandell, M.1
Story, G.M.2
Hwang, S.W.3
Viswanath, V.4
Eid, S.R.5
Petrus, M.J.6
Earley, T.J.7
Patapoutian, A.8
-
3
-
-
34447542435
-
The menthol receptor TRPM8 is the principal detector of environmental cold
-
Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D. The menthol receptor TRPM8 is the principal detector of environmental cold. Nature 448: 204-208, 2007.
-
(2007)
Nature
, vol.448
, pp. 204-208
-
-
Bautista, D.M.1
Siemens, J.2
Glazer, J.M.3
Tsuruda, P.R.4
Basbaum, A.I.5
Stucky, C.L.6
Jordt, S.E.7
Julius, D.8
-
4
-
-
46049085571
-
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels
-
Bautista DM, Sigal YM, Milstein AD, Garrison JL, Zorn JA, Tsuruda PR, Nicoll RA, Julius D. Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels. Nat Neurosci 11: 772-779, 2008.
-
(2008)
Nat Neurosci
, vol.11
, pp. 772-779
-
-
Bautista, D.M.1
Sigal, Y.M.2
Milstein, A.D.3
Garrison, J.L.4
Zorn, J.A.5
Tsuruda, P.R.6
Nicoll, R.A.7
Julius, D.8
-
5
-
-
1842453817
-
Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a flurometric imaging plate reader (FLIPR) assay
-
Behrendt HJ, Germann T, Gillen C, Hatt H, Jostock R. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a flurometric imaging plate reader (FLIPR) assay. Br J Pharmacol 141: 737-745, 2004.
-
(2004)
Br J Pharmacol
, vol.141
, pp. 737-745
-
-
Behrendt, H.J.1
Germann, T.2
Gillen, C.3
Hatt, H.4
Jostock, R.5
-
7
-
-
58149401200
-
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
-
Bhattacharya MRC, Bautista DM, Wu K, Haeberle H, Lumpkin EA, Julius D. Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons. Proc Natl Acad Sci USA 105: 20015-20020,2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20015-20020
-
-
Bhattacharya, M.R.C.1
Bautista, D.M.2
Wu, K.3
Haeberle, H.4
Lumpkin, E.A.5
Julius, D.6
-
8
-
-
0015238825
-
Tongue mechanoreceptors: Comparison of afferent fibers in the lingual nerve and chorda tympani
-
Biedenbach MA, Chan KY. Tongue mechanoreceptors: comparison of afferent fibers in the lingual nerve and chorda tympani. Brain Res 35: 584-588, 1971.
-
(1971)
Brain Res
, vol.35
, pp. 584-588
-
-
Biedenbach, M.A.1
Chan, K.Y.2
-
9
-
-
0032875319
-
Alkylamides that produce tingling paresthesia activate tactile and thermal trigeminal neurons
-
Bryant BP, Mezine I. Alkylamides that produce tingling paresthesia activate tactile and thermal trigeminal neurons. Brain Res 842: 452-460, 1999.
-
(1999)
Brain Res
, vol.842
, pp. 452-460
-
-
Bryant, B.P.1
Mezine, I.2
-
10
-
-
0031746097
-
Attenuation of formalin-induced nociceptive behaviors following local peripheral injection of gabapentin
-
Carlton SM, Zhou S. Attenuation of formalin-induced nociceptive behaviors following local peripheral injection of gabapentin. Pain 76: 201-207, 1998.
-
(1998)
Pain
, vol.76
, pp. 201-207
-
-
Carlton, S.M.1
Zhou, S.2
-
11
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389: 816-824, 1997.
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
12
-
-
0034646740
-
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
-
Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen- Zeitz KR, Koltzenburg M, Basbaum AI, Julius D. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288: 306-313, 2000.
-
(2000)
Science
, vol.288
, pp. 306-313
-
-
Caterina, M.J.1
Leffler, A.2
Malmberg, A.B.3
Martin, W.J.4
Trafton, J.5
Petersen-Zeitz, K.R.6
Koltzenburg, M.7
Basbaum, A.I.8
Julius, D.9
-
13
-
-
34247472646
-
Attenuated cold sensitivity in TRPM8 null mice
-
Colburn RW, Lubin ML, Stone DJ, Wang Y, Lawrence D, D'Andrea MR, Brandt MR, Liu Y, Flores CM, Qin N. Attenuated cold sensitivity in TRPM8 null mice. Neuron 54: 379-386, 2007.
-
(2007)
Neuron
, vol.54
, pp. 379-386
-
-
Colburn, R.W.1
Lubin, M.L.2
Stone, D.J.3
Wang, Y.4
Lawrence, D.5
D'Andrea, M.R.6
Brandt, M.R.7
Liu, Y.8
Flores, C.M.9
Qin, N.10
-
14
-
-
10644290199
-
TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells
-
Corey DP, Garcia-Anoveros J, Holt JR, Kwan KY, Lin SY, Vollrath MA, Amalfitano A, Cheung ELM, Derfler BH, Duggan A, Geleoc GSG, Gray PA, Hoffman MP, Rehm HL, Tamasauskas D, Zhang DS. TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature 432: 723-730, 2004.
-
(2004)
Nature
, vol.432
, pp. 723-730
-
-
Corey, D.P.1
Garcia-Anoveros, J.2
Holt, J.R.3
Kwan, K.Y.4
Lin, S.Y.5
Vollrath, M.A.6
Amalfitano, A.7
Cheung, E.L.M.8
Derfler, B.H.9
Duggan, A.10
Geleoc, G.S.G.11
Gray, P.A.12
Hoffman, M.P.13
Rehm, H.L.14
Tamasauskas, D.15
Zhang, D.S.16
-
15
-
-
37049057867
-
Amides of vegetable origin. 8. The constitution and configuration of the sanshools
-
Crombie L, Tayler JL. Amides of vegetable origin. 8. The constitution and configuration of the sanshools. J Chem Soc: 2760-2766, 1957.
-
(1957)
J Chem Soc
, pp. 2760-2766
-
-
Crombie, L.1
Tayler, J.L.2
-
16
-
-
9944251551
-
Pungent and tingling compounds in Asian cuisine
-
edited by Hofmann T, Ho CT, Pickenhagen W. Washington, DC: American Chemical Society
-
Galopin C, Furrer S, Geoke A. Pungent and tingling compounds in Asian cuisine. In: ACS Symposium Series: Challenges in Taste Chemistry and Biology, edited by Hofmann T, Ho CT, Pickenhagen W. Washington, DC: American Chemical Society, vol. 867, pp. 139-152, 2004.
-
(2004)
ACS Symposium Series: Challenges in Taste Chemistry and Biology
, vol.867
, pp. 139-152
-
-
Galopin, C.1
Furrer, S.2
Geoke, A.3
-
17
-
-
0030245643
-
Enhanced withdrawal responses to heat and mechanical stimuli following intraplantar injection of capsaicin in rats
-
Gilchrist HD, Allard BL, Simone DA. Enhanced withdrawal responses to heat and mechanical stimuli following intraplantar injection of capsaicin in rats. Pain 67: 179-188, 1996.
-
(1996)
Pain
, vol.67
, pp. 179-188
-
-
Gilchrist, H.D.1
Allard, B.L.2
Simone, D.A.3
-
18
-
-
0026327913
-
Capsaicin cross-desensitization on the tongue: Psychophysical evidence that oral chemical irritation is mediated by more than one sensory pathway
-
Green BG. Capsaicin cross-desensitization on the tongue: Psychophysical evidence that oral chemical irritation is mediated by more than one sensory pathway. Chem Senses 16: 675-689, 1991.
-
(1991)
Chem Senses
, vol.16
, pp. 675-689
-
-
Green, B.G.1
-
19
-
-
0023924046
-
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
-
Hargreaves K, Dubner R, Brown F, Flores C, Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32: 77-88, 1988.
-
(1988)
Pain
, vol.32
, pp. 77-88
-
-
Hargreaves, K.1
Dubner, R.2
Brown, F.3
Flores, C.4
Joris, J.5
-
20
-
-
33847796216
-
Emergence of functional sensory subtypes as defined by transient receptor potential chan- nel expression
-
Hjerling-Leffler J, Alqatari M, Ernfors P, Koltzenburg M. Emergence of functional sensory subtypes as defined by transient receptor potential chan- nel expression. J Neurosci 27: 2435-2443, 2007.
-
(2007)
J Neurosci
, vol.27
, pp. 2435-2443
-
-
Hjerling-Leffler, J.1
Alqatari, M.2
Ernfors, P.3
Koltzenburg, M.4
-
21
-
-
0037581663
-
Capsaicin binds to the intracellular domain of the capsaicin-activated ion channel
-
Jung J, Hwang SW, Kwak J, Lee SY, Kang CJ, Kim WB, Kim D, Oh U. Capsaicin binds to the intracellular domain of the capsaicin-activated ion channel. J Neurosci 19: 529-538, 1999.
-
(1999)
J Neurosci
, vol.19
, pp. 529-538
-
-
Jung, J.1
Hwang, S.W.2
Kwak, J.3
Lee, S.Y.4
Kang, C.J.5
Kim, W.B.6
Kim, D.7
Oh, U.8
-
22
-
-
0031106453
-
Amides of the fruit of Zanthoxylum spp
-
Kashiwada Y, Ito C, Katagiri H, Mase I, Komatsu K, Namba T, Ikeshiro Y. Amides of the fruit of Zanthoxylum spp. Phytochemistry 44: 1125-1127, 1997.
-
(1997)
Phytochemistry
, vol.44
, pp. 1125-1127
-
-
Kashiwada, Y.1
Ito, C.2
Katagiri, H.3
Mase, I.4
Komatsu, K.5
Namba, T.6
Ikeshiro, Y.7
-
23
-
-
77953022788
-
Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats
-
Klein AH, Sawyer CM, Carstens MI, Tsagerli MG, Tsiklauri N, Carstens E. Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats. Behav Brain Res 212: 179-186, 2010.
-
(2010)
Behav Brain Res
, vol.212
, pp. 179-186
-
-
Klein, A.H.1
Sawyer, C.M.2
Carstens, M.I.3
Tsagerli, M.G.4
Tsiklauri, N.5
Carstens, E.6
-
24
-
-
78651432017
-
Self- and cross-desensitization of oral irritation by menthol and cinnamaldehyde (CA) via peripheral interactions at trigeminal sensory neurons
-
Klein AH, Iodi Carstens M, Zanotto KL, Sawyer CM, Ivanov M, Cheung S, Carstens E. Self- and cross-desensitization of oral irritation by menthol and cinnamaldehyde (CA) via peripheral interactions at trigeminal sensory neurons. Chem Senses 36: 199-208, 2011.
-
(2011)
Chem Senses
, vol.36
, pp. 199-208
-
-
Klein, A.H.1
Carstens, I.M.2
Zanotto, K.L.3
Sawyer, C.M.4
Ivanov, M.5
Cheung, S.6
Carstens, E.7
-
25
-
-
34548309115
-
Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons
-
Koo JY, Jang Y, Cho H, Lee CH, Jang KH, Chang YH, Shin J, Oh U. Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons. Eur J Neurosci 26: 1139-1147, 2007.
-
(2007)
Eur J Neurosci
, vol.26
, pp. 1139-1147
-
-
Koo, J.Y.1
Jang, Y.2
Cho, H.3
Lee, C.H.4
Jang, K.H.5
Chang, Y.H.6
Shin, J.7
Oh, U.8
-
26
-
-
65549123596
-
TRPA1 modulates mechanotransduction in cutaneous sensory neurons
-
Kwan KY, Glazer JM, Corey DP, Rice FL, Stucky CL. TRPA1 modulates mechanotransduction in cutaneous sensory neurons. J Neurosci 29: 4808-4819,2009.
-
(2009)
J Neurosci
, vol.29
, pp. 4808-4819
-
-
Kwan, K.Y.1
Glazer, J.M.2
Corey, D.P.3
Rice, F.L.4
Stucky, C.L.5
-
27
-
-
77949834491
-
Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool
-
Lennertz RC, Tsunozaki M, Bautista DM, Stucky CL. Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool. J Neurosci 30: 4353-4361, 2010.
-
(2010)
J Neurosci
, vol.30
, pp. 4353-4361
-
-
Lennertz, R.C.1
Tsunozaki, M.2
Bautista, D.M.3
Stucky, C.L.4
-
28
-
-
63849187804
-
Variable threshold of trigeminal cold-thermosensitive neurons is determined by a balance between TRPM8 and Kv1 potassium channels
-
Madrid R, de la Peña E, Donovan-Rodriguez T, Belmonte C, Viana F. Variable threshold of trigeminal cold-thermosensitive neurons is determined by a balance between TRPM8 and Kv1 potassium channels. J Neurosci 29: 3120-3131, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 3120-3131
-
-
Madrid, R.1
de la Peña, E.2
Donovan-Rodriguez, T.3
Belmonte, C.4
Viana, F.5
-
29
-
-
64549110889
-
Synthesis and evaluation of new alkylamides derived from alpha-hydroxy sanshool, the pungent molecule in szechuan pepper
-
Menozzi-Smarrito C, Riera CE, Munari C, Le Coutre J, Robert F. Synthesis and evaluation of new alkylamides derived from alpha-hydroxy sanshool, the pungent molecule in szechuan pepper. J Agric Food Chem 57: 1982-1989, 2009.
-
(2009)
J Agric Food Chem
, vol.57
, pp. 1982-1989
-
-
Menozzi-Smarrito, C.1
Riera, C.E.2
Munari, C.3
le Coutre, J.4
Robert, F.5
-
30
-
-
17644426325
-
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing
-
Nagata K, Duggan A, Kumar G, Garcia-Anoveros J. Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci 25: 4052-4061, 2005.
-
(2005)
J Neurosci
, vol.25
, pp. 4052-4061
-
-
Nagata, K.1
Duggan, A.2
Kumar, G.3
Garcia-Anoveros, J.4
-
31
-
-
0019121328
-
Paraesthesiae from ectopic impulse generation in human sensory nerves
-
Ochoa JL, Torebjörk HE. Paraesthesiae from ectopic impulse generation in human sensory nerves. Brain 103: 835-853, 1980.
-
(1980)
Brain
, vol.103
, pp. 835-853
-
-
Ochoa, J.L.1
Torebjörk, H.E.2
-
32
-
-
18344386202
-
A TRP channel that senses cold stimuli and menthol
-
Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A. A TRP channel that senses cold stimuli and menthol. Cell 108: 705-715, 2002.
-
(2002)
Cell
, vol.108
, pp. 705-715
-
-
Peier, A.M.1
Moqrich, A.2
Hergarden, A.C.3
Reeve, A.J.4
Andersson, D.A.5
Story, G.M.6
Earley, T.J.7
Dragoni, I.8
McIntyre, P.9
Bevan, S.10
Patapoutian, A.11
-
33
-
-
70350338210
-
Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels
-
Riera CE, Menozzi-Smarrito C, Affolter M, Michlig S, Munari C, Robert F, Vogel H, Simon SA, le Coutre J. Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. Br J Pharmacol 157: 1398-1409, 2009.
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1398-1409
-
-
Riera, C.E.1
Menozzi-Smarrito, C.2
Affolter, M.3
Michlig, S.4
Munari, C.5
Robert, F.6
Vogel, H.7
Simon, S.A.8
Le Coutre, J.9
-
34
-
-
65949112242
-
Activation of lumbar spinal wide-dynamic range neurons by a sanshool derivative
-
Sawyer CM, Carstens MI, Simons CT, Slack J, McCluskey TS, Furrer S, Carstens E. Activation of lumbar spinal wide-dynamic range neurons by a sanshool derivative. J Neurophysiol 101: 1742-1748, 2009a.
-
(2009)
J Neurophysiol
, vol.101
, pp. 1742-1748
-
-
Sawyer, C.M.1
Carstens, M.I.2
Simons, C.T.3
Slack, J.4
McCluskey, T.S.5
Furrer, S.6
Carstens, E.7
-
35
-
-
79955127945
-
Responses of rat dorsal root ganglion (DRG) cells to sanshool and ther- moTRP agonists (program no. 73.3)
-
Chicago, IL: Society for Neuroscience, Online
-
Sawyer C, Klein AH, Iodi Carstens M, Simons CT, Slack J, Carstens E. Responses of rat dorsal root ganglion (DRG) cells to sanshool and ther- moTRP agonists (program no. 73.3). 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, Online, 2009b.
-
(2009)
2009 Neuroscience Meeting Planner
-
-
Sawyer, C.1
Klein, A.H.2
Carstens, I.M.3
Simons, C.T.4
Slack, J.5
Carstens, E.6
-
36
-
-
0345616438
-
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
-
Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, Earley TJ, Hergarden AC, Andersson DA, Hwang SW, McIntyre P, Jegla T, Bevan S, Patapoutian A. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112: 819-829, 2003.
-
(2003)
Cell
, vol.112
, pp. 819-829
-
-
Story, G.M.1
Peier, A.M.2
Reeve, A.J.3
Eid, S.R.4
Mosbacher, J.5
Hricik, T.R.6
Earley, T.J.7
Hergarden, A.C.8
Andersson, D.A.9
Hwang, S.W.10
McIntyre, P.11
Jegla, T.12
Bevan, S.13
Patapoutian, A.14
-
37
-
-
27644450857
-
Pungent qualities of sanshool-related compounds evaluated by a sensory test and activation of rat TRPV1
-
Sugai E, Morimitsu Y, Iwasaki Y, Morita A, Watanabe T, Kubota K. Pungent qualities of sanshool-related compounds evaluated by a sensory test and activation of rat TRPV1. Biosci Biotechnol Biochem 69: 1951-1957, 2005.
-
(2005)
Biosci Biotechnol Biochem
, vol.69
, pp. 1951-1957
-
-
Sugai, E.1
Morimitsu, Y.2
Iwasaki, Y.3
Morita, A.4
Watanabe, T.5
Kubota, K.6
-
38
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D. The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21: 531-543, 1998.
-
(1998)
Neuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
39
-
-
0031020807
-
Low-threshold mechano-receptive afferents in the human lingual nerve
-
Trulsson M, Essick GK. Low-threshold mechano-receptive afferents in the human lingual nerve. J Neurophysiol 77: 737-748, 1997.
-
(1997)
J Neurophysiol
, vol.77
, pp. 737-748
-
-
Trulsson, M.1
Essick, G.K.2
-
40
-
-
77950338675
-
Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats
-
Tsagerli MG, Tsiklauri N, Zanotto KL, Carstens MI, Klein AH, Sawyer CM, Gurtskaia G, Abzianidze E, Carstens E. Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats. Neurosci Lett 473: 233-236, 2010.
-
(2010)
Neurosci Lett
, vol.473
, pp. 233-236
-
-
Tsagerli, M.G.1
Tsiklauri, N.2
Zanotto, K.L.3
Carstens, M.I.4
Klein, A.H.5
Sawyer, C.M.6
Gurtskaia, G.7
Abzianidze, E.8
Carstens, E.9
-
41
-
-
0036183242
-
Specificity of cold thermotransduction is determined by differential ionic channel expression
-
Viana F, de la Peña E, Belmonte C. Specificity of cold thermotransduction is determined by differential ionic channel expression. Nat Neurosci 5: 254-260, 2002.
-
(2002)
Nat Neurosci
, vol.5
, pp. 254-260
-
-
Viana, F.1
de la Peña, E.2
Belmonte, C.3
-
42
-
-
0001131079
-
Distribution of unsaturated aliphatic acid-amides in Japanese Zanthoxylum species
-
Yasuda I, Takeya K, Itokawa H. Distribution of unsaturated aliphatic acid-amides in Japanese Zanthoxylum species. Phytochemistry 21: 1295-1298,1982.
-
(1982)
Phytochemistry
, vol.21
, pp. 1295-1298
-
-
Yasuda, I.1
Takeya, K.2
Itokawa, H.3
|