Effect of Human Endometrial Stromal Cell-derived Conditioned Medium on Uterine Natural Killer (uNK) Cells' Proliferation and Cytotoxicity

American Journal of Reproductive Immunology

Volumn 65, Issue 6, 2011, Pages 589-596

  Chen, Yuezhou ^a   Zhuang, Yaling ^a   Chen, Xiuying ^a   Huang, Lili ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Cytotoxicity; Endometrial stromal cells; Proliferation; Uterine natural killer cells

Indexed keywords

LACTATE DEHYDROGENASE;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DECIDUA; ENDOMETRIAL STROMAL CELL; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; MITOCHONDRION; NATURAL KILLER CELL; PHENOTYPE; PHYSIOLOGY; PREGNANCY; PRIORITY JOURNAL; STROMA CELL;

CELL LINE, TUMOR; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; CYTOTOXICITY, IMMUNOLOGIC; ENDOMETRIUM; FEMALE; FOLLICULAR PHASE; HUMANS; KILLER CELLS, NATURAL; L-LACTATE DEHYDROGENASE (CYTOCHROME); LUTEAL PHASE; PREGNANCY; PREGNANCY TRIMESTER, FIRST; STROMAL CELLS; UTERUS;

EID: 79955128058     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2010.00955.x     Document Type: Article

References (32)

1. Peel S: Granulated metrial gland cells. Adv Anat Embryol Cell Biol 1989; 115:1-112.
2. King A, Balendran N, Wooding P, Carter NP, Loke YW: CD3- leukocytes present in the human uterus during early placentation: phenotypic and morphologic characterization of the CD56++ population. Dev Immunol 1991; 1:169-190.
3. Ritson A, Bulmer JN: Isolation and functional studies of granulated lymphocytes in first trimester human decidua. Clin Exp Immunol 1989; 77:263-268.
4. Kopcow HD, Allan DS, Chen X, Rybalov B, Andzelm MM, Ge B, Strominger JL: Human decidual NK cells form immature activating synapses and are not cytotoxic. Proc Natl Acad Sci U S A 2005; 102:15563-15568.
5. Hanna J, Goldman-Wohl D, Hamani Y, Avraham I, Greenfield C, Natanson-Yaron S, Prus D, Cohen-Daniel L, Arnon TI, Manaster I, Gazit R, Yutkin V, Benharroch D, Porgador A, Keshet E, Yagel S, Mandelboim O: Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med 2006; 12:1065-1074.
6. Dunn CL, Kelly RW, Critchley HO: Decidualization of the human endometrial stromal cell: an enigmatic transformation. Reprod Biomed Online 2003; 7:151-161.
7. Blanco O, Leno-Duran E, Morales JC, Olivares EG, Ruiz-Ruiz C: Human decidual stromal cells protect lymphocytes from apoptosis. Placenta 2009; 30:677-685.
8. Keskin DB, Allan DS, Rybalov B, Andzelm MM, Stern JN, Kopcow HD, Koopman LA, Strominger JL: TGFbeta promotes conversion of CD16+ peripheral blood NK cells into CD16- NK cells with similarities to decidual NK cells. Proc Natl Acad Sci U S A 2007; 104:3378-3383.
9. Kalkunte S, Chichester CO, Gotsch F, Sentman CL, Romero R, Sharma S: Evolution of non-cytotoxic uterine natural killer cells. Am J Reprod Immunol 2008; 59:425-432.
10. Kitaya K, Yasuda J, Nakayama T, Fushiki S, Honjo H: Effect of female sex steroids on human endometrial CD16neg CD56bright natural killer cells. Fertil Steril 2003; 79(Suppl 1):730-734.
11. Dosiou C, Giudice LC: Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives. Endocr Rev 2005; 26:44-62.
12. Prabhala RH, Fahey JV, Humphrey SL, Edkins RD, Stern JE, Wira CR: Regulation by human uterine cells of PBMC proliferation: influence of the phase of the menstrual cycle and menopause. J Reprod Immunol 1998; 40:25-45.
13. Noyes RW, Hertig AT, Rock J: Dating the endometrial biopsy. Am J Obstet Gynecol 1975; 122:262-263.
14. Kitaya K, Nakayama T, Okubo T, Kuroboshi H, Fushiki S, Honjo H: Expression of macrophage inflammatory protein-1beta in human endometrium: its role in endometrial recruitment of natural killer cells. J Clin Endocrinol Metab 2003; 88:1809-1814.
15. Marcusson-Stahl M, Cederbrant K: A flow-cytometric NK-cytotoxicity assay adapted for use in rat repeated dose toxicity studies. Toxicology 2003; 193:269-279.
16. Yagel S: The developmental role of natural killer cells at the fetal-maternal interface. Am J Obstet Gynecol 2009; 201:344-350.
17. Jones RK, Bulmer JN, Searle RF: Cytotoxic activity of endometrial granulated lymphocytes during the menstrual cycle in humans. Biol Reprod 1997; 57:1217-1222.
18. Verma S, Hiby SE, Loke YW, King A: Human decidual natural killer cells express the receptor for and respond to the cytokine interleukin 15. Biol Reprod 2000; 62:959-968.
19. Kitaya K, Yamaguchi T, Honjo H: Central role of interleukin-15 in postovulatory recruitment of peripheral blood CD16(-) natural killer cells into human endometrium. J Clin Endocrinol Metab 2005; 90:2932-2940.
20. Inoue T, Kanzaki H, Imai K, Narukawa S, Katsuragawa H, Watanabe H, Hirano T, Mori T: Progesterone stimulates the induction of human endometrial CD56+ lymphocytes in an in vitro culture system. J Clin Endocrinol Metab 1996; 81:1502-1507.
21. Lash GE, Robson SC, Bulmer JN: Review: functional role of uterine natural killer (uNK) cells in human early pregnancy decidua. Placenta 2010; 31:S87-S92.
22. Kalkunte SS, Mselle TF, Norris WE, Wira CR, Sentman CL, Sharma S: Vascular endothelial growth factor C facilitates immune tolerance and endovascular activity of human uterine NK cells at the maternal-fetal interface. J Immunol 2009; 182:4085-4092.
23. Kopp HG, Placke T, Salih HR: Platelet-derived transforming growth factor-beta down-regulates NKG2D thereby inhibiting natural killer cell antitumor reactivity. Cancer Res 2009; 69:7775-7783.
24. Sugino N, Kashida S, Karube-Harada A, Takiguchi S, Kato H: Expression of vascular endothelial growth factor (VEGF) and its receptors in human endometrium throughout the menstrual cycle and in early pregnancy. Reproduction 2002; 123:379-387.
25. Arici A, MacDonald PC, Casey ML: Modulation of the levels of transforming growth factor beta messenger ribonucleic acids in human endometrial stromal cells. Biol Reprod 1996; 54:463-469.
26. Sun R, Li AL, Wei HM, Tian ZG: Expression of prolactin receptor and response to prolactin stimulation of human NK cell lines. Cell Res 2004; 14:67-73.
27. Poli A, Michel T, Theresine M, Andres E, Hentges F, Zimmer J: CD56bright natural killer (NK) cells: an important NK cell subset. Immunology 2009; 126:458-465.
28. Caligiuri MA, Zmuidzinas A, Manley TJ, Levine H, Smith KA, Ritz J: Functional consequences of interleukin 2 receptor expression on resting human lymphocytes. Identification of a novel natural killer cell subset with high affinity receptors. J Exp Med 1990; 171:1509-1526.
29. Nagler A, Lanier LL, Phillips JH: Constitutive expression of high affinity interleukin 2 receptors on human CD16-natural killer cells in vivo. J Exp Med 1990; 171:1527-1533.
30. Robertson MJ, Soiffer RJ, Wolf SF, Manley TJ, Donahue C, Young D, Herrmann SH, Ritz J: Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF. J Exp Med 1992; 175:779-788.
31. Kopcow HD, Eriksson M, Mselle TF, Damrauer SM, Wira CR, Sentman CL, Strominger JL: Human Decidual NK Cells from Gravid Uteri and NK Cells from Cycling Endometrium are Distinct NK Cell Subsets. Placenta 2010; 31:334-338.
32. Eriksson M, Meadows SK, Wira CR, Sentman CL: Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta. J Leukoc Biol 2004; 76:667-675.