Experimental evaluation of ethanolic extract of carapa guianensis L. leaf for its wound healing activity using three wound models

Evidence-based Complementary and Alternative Medicine

Volumn 2011, Issue , 2011, Pages

  Nayak, B Shivananda ^a   Kanhai, Joel ^a   Milne, David Malcolm ^a   Pereira, Lexley Pinto ^a   Swanston, William H ^b  

^a UNIVERSITY OF THE WEST INDIES   (Trinidad and Tobago)

^b North Central Regional Health Authority   (Trinidad and Tobago)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALKALOID DERIVATIVE; ANTIINFECTIVE AGENT; CARAPA GUIANENSIS EXTRACT; FLAVONOID; HYDOXYPROLINE; PLANT EXTRACT; PROLINE; SAPONIN DERIVATIVE; STEROL; TANNIN DERIVATIVE; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; WOUND HEALING PROMOTING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; CARAPA GUIANENSIS; CONTROLLED STUDY; DEAD SPACE WOUND; DRUG SCREENING; ENTEROCOCCUS FAECALIS; EPITHELIZATION; ESCHERICHIA COLI; EXCISION WOUND; GRANULATION TISSUE; INCISION WOUND; KLEBSIELLA PNEUMONIAE; MALE; MEDICINAL PLANT; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RANDOMIZED CONTROLLED TRIAL; RAT; SKIN INJURY; STAPHYLOCOCCUS AUREUS; WOUND HEALING;

EID: 79955107621     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nep160     Document Type: Article

References (29)

1. Kumar B., Vijayakumar M., Govindarajan R., Pushpangandan P., Ethanopharmacological approaches to wound healing exploring medicinal plants of India Journal of Ethnopharmacology 2007 114 103 113 (Pubitemid 47539834)
2. Jari S., Popovi Z., Maukanovi-Joci M., Djurdjevi L., Mijatovi M., Karadi B., Mitrovi M., Pavlovi P., An ethnobotanical study on the usage of wild medicinal herbs from Kopaonik Mountain (Central Serbia) Journal of Ethnopharmacology 2007 111 1 160 175
3. Iba Y., Shibata A., Kato M., Masukawa T., Possible involvement of mast cells in collagen remodeling in the late phase of cutaneous wound healing in mice International Immunopharmacology 2004 4 14 1873 1880 (Pubitemid 39504827)
4. Martin P., Wound healingaiming for perfect skin regeneration Science 1997 276 5309 75 81 (Pubitemid 27161246)
5. Roy A., Saraf S., Limonoids: overview of significant bioactive triterpenes distributed in plants kingdom Biological and Pharmaceutical Bulletin 2006 29 2 191 201 (Pubitemid 43200882)
6. Silva O. S., Romo P. R. T., Blazius R. D., Prohiro J. S., The use of andiroba Carapa guianensis as larvicide against Aedes albopictus Journal of the American Mosquito Control Association 2004 20 4 456 457 (Pubitemid 41322539)
7. Miot H. A., Batistella R. F., Batista K. D. A., Volpato D. E. C., Augusto L. S. T., Madeira N. G., Haddad V. Jr., Miot L. D. B., Comparative study of the topical effectiveness of the Andiroba oil (Carapa guianensis) and DEET 50 as repellent for Aedes sp Revista do Instituto de Medicina Tropical de Sao Paulo 2004 46 5 253 256 (Pubitemid 39481735)
8. Hammer M. L. A., Johns E. A., Tapping an Amazonian plethora: four medicinal plants of Marajo Island, Par (Brazil) Journal of Ethnopharmacology 1993 40 1 53 75 (Pubitemid 23299994)
9. Mahmood A. A., Sidik Salmah I., Wound healing activity of Carica papaya L. aqueous leaf extract in rats International Journal of Molecular Medicine and Advance Sciences 2005 1 398
10. Kapoor L. D., Singh A., Kapoort S. L., Strivastava S. N., Survey of Indian medicinal plants for Saponins. Alkaloids and flavonoids Lloydia 1969 32 297 302
11. Harborne J. B., Photochemical Methods. A Guide to Modern Techniques of Plant Analysis 1973 279 London, UK Chapman Hall
12. Morton J. J., Malone M. H., Evaluation of vulneray activity by an open wound procedure in rats Archives Internationales de Pharmacodynamie 1972 196 1 117 126
13. Asif A., Kakub G., Mehmood S., Khunum R., Gulfraz M., Wound healing activity of root extracts of Berberis lyceum Royle in rats Phytotherapy Research 2007 21 6 589 591 (Pubitemid 46910240)
14. Ehrlich H. P., Hunt T. K., Effects of cortisone and vitamin A on wound healing Annals of Surgery 1968 167 3 324 328
15. Lee K. H., Studies on mechanism of action of salicylates II. Retardation of wound healing by aspirin Journal of Pharmaceutical Sciences 1968 57 1042 1043
16. Turner R. A., Inflammatory Agent in Screening Methods of Pharmacology 1965 2nd New York, NY, USA Academic Press
17. Neuman R. E., Logan M. A., The determination of hydroxyproline Journal of Biological Chemistry 1950 184 299 306
18. Datta H. S., Mitra S. K., Patwardhan B., Wound healing activity of topical application forms based on Ayurveda. Evidence-Based Complementary and Alternative Medicine. In press
19. Shetty S., Udupa S., Udupa L., Evaluation of antioxidant and wound healing effects of alcoholic and aqueous extract of Ocimum sanctum Linn in rats Evidence-Based Complementary and Alternative Medicine 2008 5 1 95 101 (Pubitemid 351301955)
20. Kumar R., Katoch S. S., Sharma S., Adrenoceptor agonist treatment reverses denervation atrophy with augmentation of collagen proliferation in denervated mice gastrocnemius muscle Indian Journal of Experimental Biology 2006 44 371 376
21. Penido C., Conte F. P., Chagas S. S., Rodrigues C. A. B., Pereira J. F. G., Henriques M. G. M. O., Anti-allergic effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on allergen-induced vascular permeability and hyperalgesia Inflammation Research 2005 54 295 303 (Pubitemid 41185491)
22. Nayak B. S., Vinutha B., Geetha B., Sudha B., Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats Fitoterapia 2005 76 7-8 671 675 (Pubitemid 41688386)
23. Haque M. M., Rafiq Sherajee S., Ahmed Q., Hasan M. M., Treatment of external wounds by using indigenous medicinal plants and patent drugs in Guinea pigs Journal of Biological Sciences 2003 3 1126 1133
24. De Mesquita M. L., Desrivot J., Bories C., Fournet A., De Paula J. E., Grellier P., Espindola L. S., Antileishmanial and trypanocidal activity of Brazilian Cerrado plants Memorias do Instituto Oswaldo Cruz 2005 100 7 783 787 (Pubitemid 43154816)
25. Nayak B. S., Sandiford S., Maxwell A., Evaluation of the wound-healing activity of ethanolic extract of Morinda citrifolia L. leaf Evidence-based Complementary and Alternative Medicine 2009 6 3 351 356
26. Nayak B. S., Pinto Pereira L. M., Catharanthus roseus flower extract has wound-healing activity in Sprague Dawley rats BMC Complementary and Alternative Medicine 2006 6, article 41
27. de Mendona F. A., da Silva K. F., dos Santos K. K., Ribeiro Jnior K. A., Sant'Ana A. E. G., Activities of some Brazilian plants against larvae of the mosquito Aedes Aegypti Fitoterapia 2005 76 629 636 (Pubitemid 41688379)
28. Lusby P. E., Coombes A., Wilkinson J. M., Honey: a potent agent for wound healing? Journal of Wound, Ostomy, and Continence Nursing 2002 29 6 295 300
29. Simon A., Traynor K., Santos K., Blaser G., Bode U., Molan P., Medicinal honey for wound care still the latest resort Evidence-Based Complementary and Alternative Medicine 2008 5 475 479