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Volumn 11, Issue 4, 2011, Pages 541-549

Potential role of soluble VEGFR-1 in antiangiogenesis therapy for cancer

Author keywords

antiangiogenesis; cancer; hypertension; proteinuria; sFlt 1; VEGF

Indexed keywords

ADENOVIRUS VECTOR; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; CEDIRANIB; NEUROPILIN 1; NEUROPILIN 2; PLACENTAL GROWTH FACTOR; SOLUBLE VASCULOTROPIN RECEPTOR 1; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN B; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN E; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

EID: 79955105059     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.10.171     Document Type: Review
Times cited : (29)

References (68)
  • 1
    • 30944446883 scopus 로고    scopus 로고
    • Lessons from phase III clinical trials on anti-VEGF therapy for cancer
    • DOI 10.1038/ncponc0403, PII N0403
    • Jain RK, Duda DG, Clark JW, Loeffler JS. Lessons from Phase III clinical trials on anti-VEGF therapy for cancer. Nat. Clin. Pract. Oncol. 3(1), 24-40 (2006). (Pubitemid 43108832)
    • (2006) Nature Clinical Practice Oncology , vol.3 , Issue.1 , pp. 24-40
    • Jain, R.K.1    Duda, D.G.2    Clark, J.W.3    Loeffler, J.S.4
  • 2
    • 77952593669 scopus 로고    scopus 로고
    • A systems biology perspective on sVEGFR1: Its biological function pathogenic role and therapeutic use
    • Wu FTH, Stefanini MO, Mac Gabhann F et al. A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use. J. Cell. Mol. Med. 14(3), 528-552 (2010).
    • (2010) J. Cell. Mol. Med. , vol.14 , Issue.3 , pp. 528-552
    • Wu, F.T.H.1    Stefanini, M.O.2    Mac Gabhann, F.3
  • 3
    • 33645451829 scopus 로고    scopus 로고
    • Angiogenesis inhibitors and hypertension: An emerging issue
    • DOI 10.1200/JCO.2005.04.5740
    • Sica DA. Angiogenesis inhibitors and hypertension: an emerging issue. J. Clin. Oncol. 24(9), 1329-1331 (2006). (Pubitemid 46621994)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.9 , pp. 1329-1331
    • Sica, D.A.1
  • 4
    • 67650380136 scopus 로고    scopus 로고
    • Biomarkers of response and resistance to antiangiogenic therapy
    • Jain RK, Duda DG, Willett CG et al. Biomarkers of response and resistance to antiangiogenic therapy. Nat. Rev. Clin. Oncol. 6(6), 327-338 (2009).
    • (2009) Nat. Rev. Clin. Oncol. , vol.6 , Issue.6 , pp. 327-338
    • Jain, R.K.1    Duda, D.G.2    Willett, C.G.3
  • 5
    • 38049025794 scopus 로고    scopus 로고
    • Review: Side effects of approved molecular targeted therapies in solid cancers
    • Widakowich C, de Castro G Jr, de Azambuja E, Dinh P, Awada A. Review: side effects of approved molecular targeted therapies in solid cancers. Oncologist 12(12), 1443-1455 (2007).
    • (2007) Oncologist , vol.12 , Issue.12 , pp. 1443-1455
    • Widakowich, C.1    De Castro Jr., G.2    De Azambuja, E.3    Dinh, P.4    Awada, A.5
  • 6
    • 33846638744 scopus 로고    scopus 로고
    • Risks of Proteinuria and Hypertension With Bevacizumab, an Antibody Against Vascular Endothelial Growth Factor: Systematic Review and Meta-Analysis
    • DOI 10.1053/j.ajkd.2006.11.039, PII S0272638606018336
    • Zhu X, Wu S, Dahut WL, Parikh CR. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysis. Am. J. Kidney Dis. 49(2), 186-193 (2007). (Pubitemid 46178407)
    • (2007) American Journal of Kidney Diseases , vol.49 , Issue.2 , pp. 186-193
    • Zhu, X.1    Wu, S.2    Dahut, W.L.3    Parikh, C.R.4
  • 7
    • 33644586050 scopus 로고    scopus 로고
    • Reversible posterior leukoencephalopathy syndrome and bevacizumab
    • discussion
    • Glusker P, Recht L, Lane B. Reversible posterior leukoencephalopathy syndrome and bevacizumab. N. Engl. J. Med. 354(9), 980-982; discussion 980-982 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , Issue.9 , pp. 980-982
    • Glusker, P.1    Recht, L.2    Lane, B.3
  • 8
    • 33644586050 scopus 로고    scopus 로고
    • Reversible posterior leukoencephalopathy syndrome and bevacizumab
    • discussion
    • Ozcan C, Wong SJ, Hari P. Reversible posterior leukoencephalopathy syndrome and bevacizumab. N. Engl. J. Med. 354(9), 980-982; discussion 980-982 (2006).
    • (2006) N. Engl. J. Med. , vol.354 , Issue.9 , pp. 980-982
    • Ozcan, C.1    Wong, S.J.2    Hari, P.3
  • 9
    • 77950339501 scopus 로고    scopus 로고
    • Vascular endothelial growth factor targeted therapy in the perioperative setting: Implications for patient care
    • Bose D, Meric-Bernstam F, Hofstetter W et al. Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care. Lancet Oncol. 11(4), 373-382 (2010).
    • (2010) LancetOncol. , vol.11 , Issue.4 , pp. 373-382
    • Bose, D.1    Meric-Bernstam, F.2    Hofstetter, W.3
  • 10
    • 58749097799 scopus 로고    scopus 로고
    • Emergency surgery in the era of molecular treatment of solid tumours
    • Rutkowski P, Ruka W. Emergency surgery in the era of molecular treatment of solid tumours. Lancet Oncol. 10(2), 157-163 (2009).
    • (2009) LancetOncol. , vol.10 , Issue.2 , pp. 157-163
    • Rutkowski, P.1    Ruka, W.2
  • 12
    • 38549085315 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with sorafenib in patients with cancer: A systematic review and meta-analysis
    • Wu S, Chen JJ, Kudelka A, Lu J, Zhu X. Incidence and risk of hypertension with sorafenib in patients with cancer: a systematic review and meta-analysis. Lancet Oncol. 9(2), 117-123 (2008).
    • (2008) LancetOncol. , vol.9 , Issue.2 , pp. 117-123
    • Wu, S.1    Chen, J.J.2    Kudelka, A.3    Lu, J.4    Zhu, X.5
  • 13
    • 38549140603 scopus 로고    scopus 로고
    • Quantifying hypertension in patients with cancer treated with sorafenib
    • DOI 10.1016/S1470-2045(08)70009-3, PII S1470204508700093
    • Rini BI. Quantifying hypertension in patients with cancer treated with sorafenib. Lancet Oncol. 9(2), 86-87 (2008). (Pubitemid 351150123)
    • (2008) The Lancet Oncology , vol.9 , Issue.2 , pp. 86-87
    • Rini, B.I.1
  • 14
    • 85008279049 scopus 로고    scopus 로고
    • ABC of hypertension blood pressure measurement part I-sphygmomanometry: Factors common to all techniques
    • Beevers G, Lip GY, O'Brien E. ABC of hypertension. Blood pressure measurement. Part I-sphygmomanometry: factors common to all techniques. BMJ 322(7292), 981-985 (2001).
    • (2001) BMJ , vol.322 , Issue.7292 , pp. 981-985
    • Beevers, G.1    Lip, G.Y.2    O'Brien, E.3
  • 15
    • 0348010397 scopus 로고    scopus 로고
    • Sources of Variability in Blood Pressure Measurement using the Dinamap PRO 100 Automated Oscillometric Device
    • DOI 10.1093/aje/kwg274
    • Chang JJ, Rabinowitz D, Shea S. Sources of variability in blood pressure measurement using the Dinamap PRO 100 automated oscillometric device. Am. J. Epidemiol. 158(12), 1218-1226 (2003). (Pubitemid 37548792)
    • (2003) American Journal of Epidemiology , vol.158 , Issue.12 , pp. 1218-1226
    • Chang, J.J.1    Rabinowitz, D.2    Shea, S.3
  • 17
    • 38049092600 scopus 로고    scopus 로고
    • Home blood-pressure monitoring in patients receiving sunitinib
    • Azizi M, Chedid A, Oudard S. Home blood-pressure monitoring in patients receiving sunitinib. N. Engl. J. Med. 358(1), 95-97 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , Issue.1 , pp. 95-97
    • Azizi, M.1    Chedid, A.2    Oudard, S.3
  • 18
    • 34548480949 scopus 로고    scopus 로고
    • Chemotherapy agents and hypertension: A focus on angiogenesis blockade
    • DOI 10.1007/s11906-007-0058-7
    • Jain M, Townsend RR. Chemotherapy agents and hypertension: a focus on angiogenesis blockade. Curr. Hypertens. Rep. 9(4), 320-328 (2007). (Pubitemid 47377031)
    • (2007) Current Hypertension Reports , vol.9 , Issue.4 , pp. 320-328
    • Jain, M.1    Townsend, R.R.2
  • 19
    • 77955887676 scopus 로고    scopus 로고
    • Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: Phase III trial of the cancer and leukemia group B CALGB 80303
    • Kindler HL, Niedzwiecki D, Hollis D et al. Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: Phase III trial of the Cancer and Leukemia Group B (CALGB 80303).J. Clin. Oncol. 28(22), 3617-3622 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.22 , pp. 3617-3622
    • Kindler, H.L.1    Niedzwiecki, D.2    Hollis, D.3
  • 20
    • 65549150854 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
    • Van Cutsem E, Vervenne WL, Bennouna J et al. Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. J. Clin. Oncol. 27(13), 2231-2237 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.13 , pp. 2231-2237
    • Van Cutsem, E.1    Vervenne, W.L.2    Bennouna, J.3
  • 22
    • 34447310236 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 VEGFR-1/Flt-1: A dual regulator for angiogenesis
    • discussion
    • Shibuya M. Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis. Angiogenesis 9(4), 225-230; discussion 231 (2006).
    • (2006) Angiogenesis , vol.9 , Issue.4 , pp. 225-231
    • Shibuya, M.1
  • 23
    • 0025259592 scopus 로고
    • Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene flt closely related to the fms family
    • Shibuya M, Yamaguchi S, Yamane A et al. Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene 5(4), 519-524 (1990).
    • (1990) Oncogene , vol.5 , Issue.4 , pp. 519-524
    • Shibuya, M.1    Yamaguchi, S.2    Yamane, A.3
  • 25
    • 0035126012 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies
    • Helske S, Vuorela P, Carpen O et al. Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies. Mol. Hum. Reprod. 7(2), 205-210 (2001). (Pubitemid 32148349)
    • (2001) Molecular Human Reproduction , vol.7 , Issue.2 , pp. 205-210
    • Helske, S.1    Vuorela, P.2    Carpen, O.3    Hornig, C.4    Weich, H.5    Halmesmaki, E.6
  • 26
    • 36849024331 scopus 로고    scopus 로고
    • Intronic polyadenylation signal sequences and alternate splicing generate human soluble Flt1 variants and regulate the abundance of soluble Flt1 in the placenta
    • DOI 10.1096/fj.07-8809com
    • Thomas CP, Andrews JI, Liu KZ. Intronic polyadenylation signal sequences and alternate splicing generate human soluble Flt1 variants and regulate the abundance of soluble Flt1 in the placenta. FASEB J. 21(14), 3885-3895 (2007). (Pubitemid 350232346)
    • (2007) FASEB Journal , vol.21 , Issue.14 , pp. 3885-3895
    • Thomas, C.P.1    Andrews, J.I.2    Liu, K.Z.3
  • 27
    • 48249090832 scopus 로고    scopus 로고
    • A novel human-specific soluble vascular endothelial growth factor receptor 1: Cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia
    • Sela S, Itin A, Natanson-Yaron S et al. A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia. Circ. Res. 102(12), 1566-1574 (2008).
    • (2008) Circ. Res. , vol.102 , Issue.12 , pp. 1566-1574
    • Sela, S.1    Itin, A.2    Natanson-Yaron, S.3
  • 28
    • 59849090604 scopus 로고    scopus 로고
    • Novel splice variants of sFlt1 are upregulated in preeclampsia
    • Heydarian M, McCaffrey T, Florea L et al. Novel splice variants of sFlt1 are upregulated in preeclampsia. Placenta 30(3), 250-255 (2009).
    • (2009) Placenta , vol.30 , Issue.3 , pp. 250-255
    • Heydarian, M.1    McCaffrey, T.2    Florea, L.3
  • 32
    • 0037631361 scopus 로고    scopus 로고
    • Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria
    • DOI 10.1074/jbc.C300012200
    • Sugimoto H, Hamano Y, Charytan D et al. Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J. Biol. Chem. 278(15), 12605-12608 (2003). (Pubitemid 36800018)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.15 , pp. 12605-12608
    • Sugimoto, H.1    Hamanog, Y.2    Charytan, D.3    Cosgrove, D.4    Kieran, M.5    Sudhakar, A.6    Kalluri, R.7
  • 33
    • 45449090215 scopus 로고    scopus 로고
    • Efficacy of gemcitabine plus axitinib compared with gemcitabine alone in patients with advanced pancreatic cancer: An open-label randomised phase II study
    • Spano JP, Chodkiewicz C, Maurel J et al. Efficacy of gemcitabine plus axitinib compared with gemcitabine alone in patients with advanced pancreatic cancer: an open-label randomised Phase II study. Lancet 371(9630), 2101-2108 (2008).
    • (2008) Lancet , vol.371 , Issue.9630 , pp. 2101-2108
    • Spano, J.P.1    Chodkiewicz, C.2    Maurel, J.3
  • 34
    • 65549088617 scopus 로고    scopus 로고
    • Association of diastolic blood pressure dBP > 90 mmHg with overall survival OS in patients treated with axitinib AG-013736
    • Rini BI SJ, Fruehauf JP, Cohen EE et al. Association of diastolic blood pressure (dBP) > 90 mmHg with overall survival (OS) in patients treated with axitinib (AG- 013736).J. Clin. Oncol. 26(15S ), 3543 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.15 S , pp. 3543
    • Rini, B.I.S.J.1    Fruehauf, J.P.2    Cohen, E.E.3
  • 35
    • 53749093040 scopus 로고    scopus 로고
    • Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100
    • Schneider BP, Wang M, Radovich M et al. Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100. J. Clin. Oncol. 26(28), 4672-4678 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.28 , pp. 4672-4678
    • Schneider, B.P.1    Wang, M.2    Radovich, M.3
  • 36
    • 33846662478 scopus 로고    scopus 로고
    • Overexpression of soluble vascular endothelial growth factor receptor 1 in colorectal cancer: Association with progression and prognosis
    • DOI 10.1111/j.1349-7006.2007.00402.x
    • Yamaguchi T, Bando H, Mori T et al. Overexpression of soluble vascular endothelial growth factor receptor 1 in colorectal cancer: association with progression and prognosis. Cancer Sci. 98(3), 405-410 (2007). (Pubitemid 46195613)
    • (2007) Cancer Science , vol.98 , Issue.3 , pp. 405-410
    • Yamaguchi, T.1    Bando, H.2    Mori, T.3    Takahashi, K.4    Matsumoto, H.5    Yasutome, M.6    Weich, H.A.7    Toi, M.8
  • 37
    • 0036497957 scopus 로고    scopus 로고
    • Significance of vascular endothelial growth factor (VEGF)/soluble VEGF receptor-1 relationship in breast cancer
    • DOI 10.1002/ijc.10121
    • Toi M, Bando H, Ogawa T et al. Significance of vascular endothelial growth factor (VEGF)/soluble VEGF receptor-1 relationship in breast cancer. Int. J. Cancer 98(1), 14-18 (2002). (Pubitemid 34113411)
    • (2002) International Journal of Cancer , vol.98 , Issue.1 , pp. 14-18
    • Toi, M.1    Bando, H.2    Ogawa, T.3    Muta, M.4    Hornig, C.5    Weich, H.A.6
  • 38
    • 0037389767 scopus 로고    scopus 로고
    • Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A
    • Lamszus K, Ulbricht U, Matschke J et al. Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A. Clin. Cancer Res. 9(4), 1399-1405 (2003). (Pubitemid 36418393)
    • (2003) Clinical Cancer Research , vol.9 , Issue.4 , pp. 1399-1405
    • Lamszus, K.1    Ulbricht, U.2    Matschke, J.3    Brockmann, M.A.4    Fillbrandt, R.5    Westphal, M.6
  • 39
    • 1942466613 scopus 로고    scopus 로고
    • Soluble Vascular Endothelial Growth Factor Receptor 1, and Not Receptor 2, Is an Independent Prognostic Factor in Acute Myeloid Leukemia and Myelodysplastic Syndromes
    • DOI 10.1002/cncr.20187
    • Hu Q, Dey AL, Yang Y et al. Soluble vascular endothelial growth factor receptor 1, and not receptor 2, is an independent prognostic factor in acute myeloid leukemia and myelodysplastic syndromes. Cancer 100(9), 1884-1891 (2004). (Pubitemid 38529566)
    • (2004) Cancer , vol.100 , Issue.9 , pp. 1884-1891
    • Hu, Q.1    Dey, A.L.2    Yang, Y.3    Shen, Y.4    Jilani, I.B.5    Estey, E.H.6    Kantarjian, H.M.7    Giles, F.J.8    Albitar, M.9
  • 40
    • 15244362063 scopus 로고    scopus 로고
    • Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer
    • DOI 10.1038/sj.bjc.6602374
    • Bando H, Weich HA, Brokelmann M et al. Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer. Brit. J. Cancer 92(3), 553-561 (2005). (Pubitemid 40395537)
    • (2005) British Journal of Cancer , vol.92 , Issue.3 , pp. 553-561
    • Bando, H.1    Weich, H.A.2    Brokelmann, M.3    Horiguchi, S.4    Funata, N.5    Ogawa, T.6    Toi, M.7
  • 41
    • 77951729010 scopus 로고    scopus 로고
    • The ratio of serum placenta growth factor to soluble vascular endothelial growth factor receptor-1 predicts the prognosis of hepatocellular carcinoma
    • Nagaoka S, Yoshida T, Akiyoshi J et al. The ratio of serum placenta growth factor to soluble vascular endothelial growth factor receptor-1 predicts the prognosis of hepatocellular carcinoma. Oncol. Rep. 23(6), 1647-1654 (2010).
    • (2010) Oncol. Rep. , vol.23 , Issue.6 , pp. 1647-1654
    • Nagaoka, S.1    Yoshida, T.2    Akiyoshi, J.3
  • 42
    • 55949086925 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor/soluble vascular endothelial growth factor receptor 1 ratio is an independent prognostic marker in pancreatic cancer
    • Chang YT, Chang MC, Wei SC et al. Serum vascular endothelial growth factor/soluble vascular endothelial growth factor receptor 1 ratio is an independent prognostic marker in pancreatic cancer. Pancreas 37(2), 145-150 (2008).
    • (2008) Pancreas , vol.37 , Issue.2 , pp. 145-150
    • Chang, Y.T.1    Chang, M.C.2    Wei, S.C.3
  • 43
    • 24644469670 scopus 로고    scopus 로고
    • Soluble VEGF/sFLt1 ratio is an independent predictor of AML patient out come
    • DOI 10.1080/10245330500065797
    • Aref S, El Sherbiny M, Goda T et al. Soluble VEGF/sFLt1 ratio is an independent predictor of AML patient out come. Hematology 10(2), 131-134 (2005). (Pubitemid 41800786)
    • (2005) Hematology , vol.10 , Issue.2 , pp. 131-134
    • Aref, S.1    El Sherbiny, M.2    Goda, T.3    Fouda, M.4    Al Askalany, H.5    Abdalla, D.6
  • 44
    • 33748160118 scopus 로고    scopus 로고
    • Anti-angiogenic inhibition of tumor growth by systemic delivery of PEI-g-PEG-RGD/pCMV-sFlt-1 complexes in tumor-bearing mice
    • DOI 10.1016/j.jconrel.2006.05.029, PII S0168365906002495
    • Kim WJ, Yockman JW, Jeong JH et al. Anti-angiogenic inhibition of tumor growth by systemic delivery of PEI-g-PEG-RGD/pCMV-sFlt-1 complexes in tumor-bearing mice. J. Control. Release 114(3), 381-388 (2006). (Pubitemid 44310812)
    • (2006) Journal of Controlled Release , vol.114 , Issue.3 , pp. 381-388
    • Kim, W.J.1    Yockman, J.W.2    Jeong, J.H.3    Christensen, L.V.4    Lee, M.5    Kim, Y.-H.6    Kim, S.W.7
  • 45
    • 34247126542 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy with systemically administered sFlt-1 plasmid DNA in engineered gelatin-based nanovectors
    • DOI 10.1038/sj.cgt.7701041, PII 7701041
    • Kommareddy S, Amiji M. Antiangiogenic gene therapy with systemically administered sFlt-1 plasmid DNA in engineered gelatin-based nanovectors. Cancer Gene Ther. 14(5), 488-498 (2007). (Pubitemid 46588197)
    • (2007) Cancer Gene Therapy , vol.14 , Issue.5 , pp. 488-498
    • Kommareddy, S.1    Amiji, M.2
  • 46
    • 0034655246 scopus 로고    scopus 로고
    • Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ
    • Takayama K, Ueno H, Nakanishi Y et al. Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res. 60(8), 2169-2177 (2000). (Pubitemid 30225180)
    • (2000) Cancer Research , vol.60 , Issue.8 , pp. 2169-2177
    • Takayama, K.1    Ueno, H.2    Nakanishi, Y.3    Sakamoto, T.4    Inoue, K.5    Shimizu, K.6    Oohashi, H.7    Hara, N.8
  • 48
    • 20144373435 scopus 로고    scopus 로고
    • Suppression of tumor growth by oncolytic adenovirus-mediated delivery of an antiangiogenic gene, Soluble Flt-1
    • DOI 10.1016/j.ymthe.2004.12.015, PII S1525001604015928
    • Zhang Z, Zou W, Wang J et al. Suppression of tumor growth by oncolytic adenovirus-mediated delivery of an antiangiogenic gene, soluble Flt-1. Mol. Ther. 11(4), 553-562 (2005). (Pubitemid 40353113)
    • (2005) Molecular Therapy , vol.11 , Issue.4 , pp. 553-562
    • Zhang, Z.1    Zou, W.2    Wang, J.3    Gu, J.4    Dang, Y.5    Li, B.6    Zhao, L.7    Qian, C.8    Qian, Q.9    Liu, X.10
  • 49
    • 2442640516 scopus 로고    scopus 로고
    • Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer
    • DOI 10.1158/0008-5472.CAN-04-0304
    • Sako A, Kitayama J, Koyama H et al. Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer. Cancer Res. 64(10), 3624-3628 (2004). (Pubitemid 38657941)
    • (2004) Cancer Research , vol.64 , Issue.10 , pp. 3624-3628
    • Sako, A.1    Kitayama, J.2    Koyama, H.3    Ueno, H.4    Uchida, H.5    Hamada, H.6    Nagawa, H.7
  • 51
    • 77950575701 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-1
    • Oba M, Vachutinsky Y, Miyata K et al. Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-1. Mol. Pharm. 7(2), 501-509 (2010).
    • (2010) Mol. Pharm. , vol.7 , Issue.2 , pp. 501-509
    • Oba, M.1    Vachutinsky, Y.2    Miyata, K.3
  • 54
    • 63649107910 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy with soluble VEGFR-1-2 and-3 reduces the growth of solid human ovarian carcinoma in mice
    • Sallinen H, Anttila M, Narvainen J et al. Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice. Mol. Ther. 17(2), 278-284 (2009).
    • (2009) Mol. Ther. , vol.17 , Issue.2 , pp. 278-284
    • Sallinen, H.1    Anttila, M.2    Narvainen, J.3
  • 57
    • 34547142109 scopus 로고    scopus 로고
    • Soluble fms-like tyrosine kinase-1 expression inhibits the growth of multiple myeloma in nude mice
    • DOI 10.1111/j.1745-7270.2007.00310.x
    • Liu JR, Li J, Su C, Huang BH, Luo SK. Soluble fms-like tyrosine kinase-1 expression inhibits the growth of multiple myeloma in nude mice. Acta Bioch. Bioph. Sin. 39(7), 499-506 (2007). (Pubitemid 47117599)
    • (2007) Acta Biochimica et Biophysica Sinica , vol.39 , Issue.7 , pp. 499-506
    • Liu, J.1    Li, J.2    Su, C.3    Huang, B.4    Luo, S.5
  • 58
    • 34147139975 scopus 로고    scopus 로고
    • Combined effects of soluble vascular endothelial growth factor receptor Flt-1 gene therapy and cisplatin chemotherapy in human tongue carcinoma xenografts
    • Gao ZN, Wei YQ, Yang PS et al. Combined effects of soluble vascular endothelial growth factor receptor Flt-1 gene therapy and cisplatin chemotherapy in human tongue carcinoma xenografts. Oral Oncol. 43(5), 477-483 (2007).
    • (2007) Oral Oncol. , vol.43 , Issue.5 , pp. 477-483
    • Gao, Z.N.1    Wei, Y.Q.2    Yang, P.S.3
  • 59
    • 77957961198 scopus 로고    scopus 로고
    • Tumor microenvironment modifications induced by soluble VEGF receptor expression in a rat liver metastasis model
    • Bertin S, Mohsen-Kanson T, Baque P et al. Tumor microenvironment modifications induced by soluble VEGF receptor expression in a rat liver metastasis model. Cancer Lett. 298(2), 264-272 (2010).
    • (2010) CancerLett. , vol.298 , Issue.2 , pp. 264-272
    • Bertin, S.1    Mohsen-Kanson, T.2    Baque, P.3
  • 61
    • 48749121296 scopus 로고    scopus 로고
    • VEGF blockade decelerates the growth of a murine experimental osteosarcoma
    • Yin D, Jia T, Gong W et al. VEGF blockade decelerates the growth of a murine experimental osteosarcoma. Int. J. Oncol. 33(2), 253-259 (2008).
    • (2008) Int. J. Oncol. , vol.33 , Issue.2 , pp. 253-259
    • Yin, D.1    Jia, T.2    Gong, W.3
  • 63
    • 56049091266 scopus 로고    scopus 로고
    • Anti-angiogenesis therapy based on the bone marrow-derived stromal cells genetically engineered to express sFlt-1 in mouse tumor model
    • Hu M, Yang JL, Teng H et al. Anti-angiogenesis therapy based on the bone marrow-derived stromal cells genetically engineered to express sFlt-1 in mouse tumor model. BMC Cancer 8, 306 (2008).
    • (2008) BMC Cancer , vol.8 , pp. 306
    • Hu, M.1    Yang, J.L.2    Teng, H.3
  • 64
    • 67649946279 scopus 로고    scopus 로고
    • Efficacy safety and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: A Phase II study
    • Zhu AX, Sahani DV, Duda DG et al. Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a Phase II study. J. Clin. Oncol. 27(18), 3027-3035 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.18 , pp. 3027-3035
    • Zhu, A.X.1    Sahani, D.V.2    Duda, D.G.3
  • 65
    • 77954720781 scopus 로고    scopus 로고
    • Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor in patients with recurrent glioblastoma
    • Batchelor TT, Duda DG, di Tomaso E et al. Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. J. Clin. Oncol. 28(17), 2817-2823 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.17 , pp. 2817-2823
    • Batchelor, T.T.1    Duda, D.G.2    Di Tomaso, E.3
  • 66
    • 77954991606 scopus 로고    scopus 로고
    • Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer
    • Duda DG, Willett CG, Ancukiewicz M et al. Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer. Oncologist 15(6), 577-583 (2010).
    • (2010) Oncologist , vol.15 , Issue.6 , pp. 577-583
    • Duda, D.G.1    Willett, C.G.2    Ancukiewicz, M.3
  • 67
    • 67649921334 scopus 로고    scopus 로고
    • Efficacy safety and biomarkers of neoadjuvant bevacizumab radiation therapy and fluorouracil in rectal cancer: A multidisciplinary phase II study
    • Willett CG, Duda DG, di Tomaso E et al. Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary Phase II study. J. Clin. Oncol. 27(18), 3020-3026 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.18 , pp. 3020-3026
    • Willett, C.G.1    Duda, D.G.2    Di Tomaso, E.3
  • 68
    • 0032795396 scopus 로고    scopus 로고
    • Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA
    • DOI 10.1016/S0022-1759(99)00065-4, PII S0022175999000654
    • Hornig C, Behn T, Bartsch W, Yayon A, Weich HA. Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA. J. Immunol. Methods 226(1-2), 169-177 (1999). (Pubitemid 29336541)
    • (1999) Journal of Immunological Methods , vol.226 , Issue.1-2 , pp. 169-177
    • Hornig, C.1    Behn, T.2    Bartsch, W.3    Yayon, A.4    Weich, H.A.5


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