Effects of exogenous apelin-12 on functional and metabolic recovery of isolated rat heart after ischemia

Kardiologiya

Volumn 50, Issue 10, 2010, Pages 44-49

  Pisarenko, O I ^a   Shulzhenko, V S ^a   Pelogeykina, Yu A ^a   Studneva, I M ^a   Khatri, D N ^a   Bespalova, Z D ^a   Azmuko, A A ^a   Sidorova, M V ^a   Palkeeva, M E ^a  

^a INSTITUTE OF EXPERIMENTAL CARDIOLOGY   (Russian Federation)

Author keywords

Apelin 12; Cell membrane damage; Energy metabolism; Myocardial ischemia and reperfusion

Indexed keywords

APELIN 12 PEPTIDE; APELIN-12 PEPTIDE; PROTECTIVE AGENT; SIGNAL PEPTIDE;

ANIMAL; ANIMAL MODEL; ARTICLE; CONVALESCENCE; CORONARY ARTERY BLOOD FLOW; DRUG ADMINISTRATION; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; ENERGY METABOLISM; HEART; HEART CONTRACTION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SYNTHESIS; WISTAR RAT;

ANIMALS; CORONARY CIRCULATION; DRUG ADMINISTRATION ROUTES; DRUG ADMINISTRATION SCHEDULE; ENERGY METABOLISM; HEART; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MODELS, ANIMAL; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PROTECTIVE AGENTS; RATS; RATS, WISTAR; RECOVERY OF FUNCTION;

EID: 79955101663     PISSN: 00229040     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Verma S., Fedak P.W., Weiself R.D. et al. Fundamentals of reperfusion injury for the clinical cardiologist. Circulation 2002; 105:2332-2336. (Pubitemid 34556381)
2. Infanger M., Faramani S., Grosst J. et al. Expression of vascular endothelial growth factor and receptor tyrosine kinases in cardiac ischemia/reperfusion injury. Cardiovasc Pathol 2007;16:291-299. (Pubitemid 47375119)
3. Smith C.C., Mocanu M.M., Davidson S.M. et al. Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects. Br J Pharmacol 2006;149:5-13. (Pubitemid 44299063)
4. Berry M.F., Pirolli T.J., Jayasankar V. et al. Apelin has in vivo inotropic effects on normal and failing hearts. Circulation 2004;110: II187-II193. (Pubitemid 39263721)
5. Boucher J., Masri B., Daviaud D. et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology 2005;146:1764-1771. (Pubitemid 40396885)
6. Tatemoto K., Takayama K., Zou M.X. et al. The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism. Regul Pept 2001;99:87-92. (Pubitemid 32522535)
7. Chen M.M., Ashley E.A., Deng D.X. et al. Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation 2003; 108:1432-1439. (Pubitemid 37176447)
8. Simpkin J.C., Yellon D.M., Davidson S.M. et al. Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemia-reperfusion injury. Basic Res Cardiol 2007;102:518-528. (Pubitemid 47578397)
9. Kleinz M.J., Baxter G.F. Apelin reduces myocardial reperfiision injury independently of PI3K/Akt and P70S6 kinase. Regul Pept 2008;146:271-277.
10. Zeng X.J., Zhang L.K., Wang H.X. et al. Apelin protects heart against ischemia/reperfiision injury in rat. Peptides 2009;30:1144-1152.
11. Smith C. C., Mocanu M.M., Bowen J. et al. Temporal changes in myocardial salvage kinases during reperfiision following ischemia: studies involving the cardioprotective adipocytokine apelin. Cardiovasc Drugs Ther 2007;21:409-414. (Pubitemid 350231508)
12. Masri B., Lahlou H., Mazarguil H. et al. Apelin (65-77) activates extracellular signalregulated kinases via a PTX-sensitive G protein. Biochem Biophys Res Commun 2004;290:539-545.
13. Kawamata Y., Habata Y., Fukusumi S. et al. Molecular properties of apelin: tissue distribution and receptor binding. Biochim Biophys Acta 2001;1538:162-171. (Pubitemid 32402239)
14. Lamprecht W., Trautschold I. Creatine phosphane. Determination with CK, HK and G6P-DH. In: Methods of enzymatic analysis. Beigmeyer H.U. (ed). Academic Press. N.Y. 1974:1777-1781.
15. Jaworek D., Gruber W., Bergmeyer H.U. Adenosine-5'-diphosphate and adenosine-5'-monophosphate. In: Methods of enzymatic analysis. Bergmeyer H.U. (ed). Academic Press. N.Y. 1974:2127-2131.
16. Bernt E., Bergmeyer H.U., MolleringH. Creatine. In: Methods of enzymatic analysis. Bergmeyer H.U. (ed). Academic Press. N.Y. 1974:1772-1776.
17. Gutman I., Wahlenfeld A.W.L. L-(±)-Lactate. Determination with LDH and NAD. In: Methods of enzymatic analysis. Bergmeyer H.U. (ed). Academic Press. N.Y. 1974:1464-1467.
18. Bucher T., Czpk R., Lamprecht W., Latzko E. Pyruvate. In: Methods of enzymatic analysis. Bergmeyer H.U. (ed). Academic Press. N.Y. 1963:2253-2259.
19. Jia Y.X., Lu Z.F., Zhang J. et al. Apelin activates L-anjinine/nitric oxide synthase/nitric oxide pathway in rat aortas. Peptides 2007;28:2023-2029. (Pubitemid 47419100)
20. Cheng X., Cheng X.S., Pang C.C. Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats. Eur J Pharmacol 2003;470:171-175. (Pubitemid 36694473)
21. Clancy R.M., Leszcynska-Piziak J., Abramson S.B. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest 1992;90:1116-1121.
22. Shultz R., Kelm M., Heusch G. Nitric oxide in myocardial ischemia/reperfiision injury. Cardiovasc Res 2004;61:402-413. (Pubitemid 38210147)
23. Marklund S., Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974;47:469-474.
24. Ronkalnen V.P., Ronkalnen J.J., Hanninen S.L. et al. Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. FASEB J 2007;8:1821-1830. (Pubitemid 46855628)
25. Atluri P., Marine K.J., Liao G.P. et al. Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression. Cell Mol Biol Lett 2007;1:127-138. (Pubitemid 46786647)
26. Ashley E.A., Powers J., Chen M. et al. The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Cardiovasc Res 2005;65:73-82. (Pubitemid 40038480)