-
1
-
-
0032426667
-
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory
-
DOI 10.1073/pnas.95.25.15020
-
M Barad R Bourtchouladze DG Winder H Golan E Kandel 1998 Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory Proc Natl Acad Sci USA 95 15020 15025 9844008 10.1073/pnas.95.25.15020 1:CAS:528:DyaK1cXotVGls7o%3D (Pubitemid 29003749)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 15020-15025
-
-
Barad, M.1
Bourtchouladze, R.2
Winder, D.G.3
Golan, H.4
Kandel, E.5
-
2
-
-
0032816443
-
Stimulators of the cAMP cascade reverse amnesia induced by intra- amygdala but not intrahippocampal KN-62 administration
-
DOI 10.1006/nlme.1998.3830
-
DM Barros LA Izquierdo MK Sant'Anna J Quevedo JH Medina JL McGaugh I Izquierdo 1999 Stimulators of the cAMP cascade reverse amnesia induced by intra-amygdala but not intrahippocampal KN-62 administration Neurobiol Learn Mem 71 94 103 9889075 10.1006/nlme.1998.3830 1:CAS:528:DyaK1MXpvVOnsQ%3D%3D (Pubitemid 29393794)
-
(1999)
Neurobiology of Learning and Memory
, vol.71
, Issue.1
, pp. 94-103
-
-
Barros, D.M.1
Izquierdo, L.A.2
Sant'Anna, M.K.3
Quevedo, J.4
Medina, J.H.5
McGaugh, J.L.6
Izquierdo, I.7
-
3
-
-
0028802726
-
Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
-
7480160 1:CAS:528:DyaK28XlvVyj
-
JA Beavo 1995 Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms Physiol Rev 75 725 748 7480160 1:CAS:528:DyaK28XlvVyj
-
(1995)
Physiol Rev
, vol.75
, pp. 725-748
-
-
Beavo, J.A.1
-
4
-
-
0036729478
-
Cyclic nucleotide research - Still expanding after half a century
-
DOI 10.1038/nrm911
-
JA Beavo LL Brunton 2002 Cyclic nucleotide research-still expanding after half a century Nat Rev Mol Cell Biol 3 710 718 12209131 10.1038/nrm911 1:CAS:528:DC%2BD38Xmslansrk%3D (Pubitemid 34987792)
-
(2002)
Nature Reviews Molecular Cell Biology
, vol.3
, Issue.9
, pp. 710-718
-
-
Beavo, J.A.1
Brunton, L.L.2
-
5
-
-
13244252317
-
Reproducible loss of CA1 neurons following carotid artery occlusion combined with halothane-induced hypotension
-
DOI 10.1016/j.brainres.2004.11.033, PII S0006899304018359
-
O Bendel K Alkass T Bueters M von Euler G von Euler 2005 Reproducible loss of CA1 neurons following carotid artery occlusion combined with halothane-induced hypotension Brain Res 1033 135 142 15694917 10.1016/j.brainres.2004.11.033 1:CAS:528:DC%2BD2MXhtVOrtb8%3D (Pubitemid 40193407)
-
(2005)
Brain Research
, vol.1033
, Issue.2
, pp. 135-142
-
-
Bendel, O.1
Alkass, K.2
Bueters, T.3
Von Euler, M.4
Von Euler, G.5
-
6
-
-
28044445105
-
Reappearance of hippocampal CA1 neurons after ischemia is associated with recovery of learning and memory
-
DOI 10.1038/sj.jcbfm.9600153, PII 9600153
-
O Bendel T Bueters M von Euler S Ove Ogren J Sandin G von Euler 2005 Reappearance of hippocampal CA1 neurons after ischemia is associated with recovery of learning and memory J Cereb Blood Flow Metab 25 1586 1595 15917746 10.1038/sj.jcbfm.9600153 1:CAS:528:DC%2BD2MXhtlGgs73J (Pubitemid 41683170)
-
(2005)
Journal of Cerebral Blood Flow and Metabolism
, vol.25
, Issue.12
, pp. 1586-1595
-
-
Bendel, O.1
Bueters, T.2
Von Euler, M.3
Ove Ogren, S.4
Sandin, J.5
Von Euler, G.6
-
7
-
-
0031465545
-
Delayed treatment with rolipram protects against neuronal damage following global ischemia in rats
-
F Block A Tondar W Schmidt M Schwarz 1997 Delayed treatment with rolipram protects against neuronal damage following global ischemia in rats NeuroReport 8 3829 3832 9427378 10.1097/00001756-199712010-00033 1:CAS:528: DyaK2sXotVCltrs%3D (Pubitemid 28004883)
-
(1997)
NeuroReport
, vol.8
, Issue.17
, pp. 3829-3832
-
-
Block, F.1
Tondar, A.2
Schmidt, W.3
Schwarz, M.4
-
8
-
-
0042337368
-
A mouse model of Rubinstein-Taybi syndrome: Defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4
-
DOI 10.1073/pnas.1834280100
-
R Bourtchouladze R Lidge R Catapano J Stanley S Gossweiler D Romashko R Scott T Tully 2003 A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4 Proc Natl Acad Sci USA 100 10518 10522 12930888 10.1073/pnas.1834280100 1:CAS:528:DC%2BD3sXntFynsLY%3D (Pubitemid 37071910)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.18
, pp. 10518-10522
-
-
Bourtchouladze, R.1
Lidge, R.2
Catapano, R.3
Stanley, J.4
Gossweiler, S.5
Romashko, D.6
Scott, R.7
Tully, T.8
-
9
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
942051 10.1016/0003-2697(76)90527-3 1:CAS:528:DyaE28XksVehtrY%3D
-
MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 942051 10.1016/0003-2697(76)90527-3 1:CAS:528: DyaE28XksVehtrY%3D
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
10
-
-
74049158987
-
Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety
-
20037581 10.1038/nbt.1598 1:CAS:528:DC%2BD1MXhs1SktbzJ
-
AB Burgin OT Magnusson J Singh P Witte BL Staker JM Bjornsson M Thorsteinsdottir S Hrafnsdottir T Hagen AS Kiselyov LJ Stewart ME Gurney 2010 Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety Nat Biotechnol 28 63 70 20037581 10.1038/nbt.1598 1:CAS:528:DC%2BD1MXhs1SktbzJ
-
(2010)
Nat Biotechnol
, vol.28
, pp. 63-70
-
-
Burgin, A.B.1
Magnusson, O.T.2
Singh, J.3
Witte, P.4
Staker, B.L.5
Bjornsson, J.M.6
Thorsteinsdottir, M.7
Hrafnsdottir, S.8
Hagen, T.9
Kiselyov, A.S.10
Stewart, L.J.11
Gurney, M.E.12
-
11
-
-
77957354074
-
Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats
-
10.1007/s00213-010-1943-3 1:CAS:528:DC%2BC3cXovFCgu7g%3D
-
YF Cheng C Wang HB Lin YF Li Y Huang JP Xu HT Zhang 2010 Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats Psychopharmacology (Berl) 212 181 191 10.1007/s00213-010-1943-3 1:CAS:528:DC%2BC3cXovFCgu7g%3D
-
(2010)
Psychopharmacology (Berl)
, vol.212
, pp. 181-191
-
-
Cheng, Y.F.1
Wang, C.2
Lin, H.B.3
Li, Y.F.4
Huang, Y.5
Xu, J.P.6
Zhang, H.T.7
-
12
-
-
0037458648
-
Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling
-
DOI 10.1074/jbc.R200029200
-
M Conti W Richter C Mehats G Livera JY Park C Jin 2003 Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling J Biol Chem 278 5493 5496 12493749 10.1074/jbc.R200029200 1:CAS:528:DC%2BD3sXht1aqsr4%3D (Pubitemid 36800786)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.8
, pp. 5493-5496
-
-
Conti, M.1
Richter, W.2
Mehats, C.3
Livera, G.4
Park, J.-Y.5
Jin, C.6
-
13
-
-
34247889972
-
Therapeutic benefit of PDE4 inhibitors in inflammatory diseases
-
SG Dastidar D Rajagopal A Ray 2007 Therapeutic benefit of PDE4 inhibitors in inflammatory diseases Curr Opin Investig Drugs 8 364 372 17520865 1:CAS:528:DC%2BD2sXmsFOksr4%3D (Pubitemid 46700993)
-
(2007)
Current Opinion in Investigational Drugs
, vol.8
, Issue.5
, pp. 364-372
-
-
Dastidar, S.G.1
Rajagopal, D.2
Ray, A.3
-
14
-
-
0027203084
-
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons
-
U Frey YY Huang ER Kandel 1993 Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons Science 260 1661 1664 8389057 10.1126/science.8389057 1:CAS:528:DyaK3sXksVWmu7o%3D (Pubitemid 23247151)
-
(1993)
Science
, vol.260
, Issue.5114
, pp. 1661-1664
-
-
Frey, U.1
Huang, Y.-Y.2
Kandel, E.R.3
-
15
-
-
0036460142
-
2+-activated potassium channels via oxidation modulation in rat hippocampal CA1 pyramidal neurons
-
DOI 10.1046/j.1460-9568.2002.01908.x
-
LW Gong TM Gao H Huang ZY Zhuang Z Tong 2002 Transient forebrain ischemia induces persistent hyperactivity of large conductance Ca2+ -activated potassium channels via oxidation modulation in rat hippocampal CA1 pyramidal neurons Eur J Neurosci 15 779 783 11886457 10.1046/j.1460-9568.2002.01908.x (Pubitemid 35471945)
-
(2002)
European Journal of Neuroscience
, vol.15
, Issue.4
, pp. 779-783
-
-
Gong, L.-W.1
Gao, T.M.2
Huang, H.3
Zhuang, Z.-Y.4
Tong, Z.5
-
16
-
-
0141819194
-
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke
-
DOI 10.1038/ng1245
-
S Gretarsdottir G Thorleifsson ST Reynisdottir A Manolescu S Jonsdottir T Jonsdottir T Gudmundsdottir SM Bjarnadottir OB Einarsson HM Gudjonsdottir, et al. 2003 The gene encoding phosphodiesterase 4D confers risk of ischemic stroke Nat Genet 35 131 138 14517540 10.1038/ng1245 1:CAS:528:DC%2BD3sXns1WgtLs%3D (Pubitemid 37187631)
-
(2003)
Nature Genetics
, vol.35
, Issue.2
, pp. 131-138
-
-
Gretarsdottir, S.1
Thorleifsson, G.2
Reynisdottir, S.Th.3
Manolescu, A.4
Jonsdottir, S.5
Jonsdottir, T.6
Gudmundsdottir, T.7
Bjarnadottir, S.M.8
Einarsson, O.B.9
Gudjonsdottir, H.M.10
Hawkins, M.11
Gudmundsson, G.12
Gudmundsdottir, H.13
Andrason, H.14
Gudmundsdottir, A.S.15
Sigurdardottir, M.16
Chou, T.T.17
Nahmias, J.18
Goss, S.19
Sveinbjornsdottir, S.20
Valdimarsson, E.M.21
Jakobsson, F.22
Agnarsson, U.23
Gudnason, V.24
Thorgeirsson, G.25
Fingerle, J.26
Gurney, M.27
Gudbjartsson, D.28
Frigge, M.L.29
Kong, A.30
Stefansson, K.31
Gulcher, J.R.32
more..
-
17
-
-
0030956323
-
Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training
-
DOI 10.1073/pnas.94.6.2693
-
JF Guzowski JL McGaugh 1997 Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training Proc Natl Acad Sci USA 94 2693 2698 9122258 10.1073/pnas.94.6.2693 1:CAS:528:DyaK2sXhvF2ktrY%3D (Pubitemid 27136938)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.6
, pp. 2693-2698
-
-
Guzowski, J.F.1
Mcgaugh, J.L.2
-
18
-
-
18044395132
-
Characterizing learning deficits and hippocampal neuron loss following transient global cerebral ischemia in rats
-
DOI 10.1016/j.brainres.2005.02.030
-
RE Hartman JM Lee GJ Zipfel DF Wozniak 2005 Characterizing learning deficits and hippocampal neuron loss following transient global cerebral ischemia in rats Brain Res 1043 48 56 15862517 10.1016/j.brainres.2005.02.030 1:CAS:528:DC%2BD2MXjs1Gjsbo%3D (Pubitemid 40603371)
-
(2005)
Brain Research
, vol.1043
, Issue.1-2
, pp. 48-56
-
-
Hartman, R.E.1
Lee, J.M.2
Zipfel, G.J.3
Wozniak, D.F.4
-
19
-
-
0035224418
-
PDE4 cAMP-specific phosphodiesterases
-
PII S0079660301690494
-
MD Houslay 2001 PDE4 cAMP-specific phosphodiesterases Prog Nucleic Acid Res Mol Biol 69 249 315 11550796 10.1016/S0079-6603(01)69049-4 1:CAS:528:DC%2BD3MXntFGluro%3D (Pubitemid 33805840)
-
(2001)
Progress in Nucleic Acid Research and Molecular Biology
, vol.69
, pp. 249-315
-
-
Houslay, M.D.1
-
20
-
-
33847206404
-
Neuroprotective effect of exogenous microglia in global brain ischemia
-
16820801 10.1038/sj.jcbfm.9600362 1:CAS:528:DC%2BD2sXjtlKitLY%3D
-
F Imai H Suzuki J Oda T Ninomiya K Ono H Sano M Sawada 2007 Neuroprotective effect of exogenous microglia in global brain ischemia J Cereb Blood Flow Metab 27 488 500 16820801 10.1038/sj.jcbfm.9600362 1:CAS:528:DC%2BD2sXjtlKitLY%3D
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 488-500
-
-
Imai, F.1
Suzuki, H.2
Oda, J.3
Ninomiya, T.4
Ono, K.5
Sano, H.6
Sawada, M.7
-
21
-
-
0031048406
-
Ameliorating effects of rolipram on experimentally induced impairments of learning and memory in rodents
-
DOI 10.1016/S0014-2999(96)00969-7, PII S0014299996009697
-
T Imanishi A Sawa Y Ichimaru M Miyashiro S Kato T Yamamoto S Ueki 1997 Ameliorating effects of rolipram on experimentally induced impairments of learning and memory in rodents Eur J Pharmacol 321 273 278 9085037 10.1016/S0014-2999(96)00969-7 1:STN:280:DyaK2s3jvFektw%3D%3D (Pubitemid 27105928)
-
(1997)
European Journal of Pharmacology
, vol.321
, Issue.3
, pp. 273-278
-
-
Imanishi, T.1
Sawa, A.2
Ichimaru, Y.3
Miyashiro, M.4
Kato, S.5
Yamamoto, T.6
Ueki, S.7
-
23
-
-
29644440311
-
Cognitive profile of subcortical ischaemic vascular disease
-
DOI 10.1136/jnnp.2005.069120
-
H Jokinen H Kalska R Mantyla T Pohjasvaara R Ylikoski M Hietanen O Salonen M Kaste T Erkinjuntti 2006 Cognitive profile of subcortical ischaemic vascular disease J Neurol Neurosurg Psychiatry 77 28 33 16361588 10.1136/jnnp.2005.069120 1:STN:280:DC%2BD2MnntlOrsg%3D%3D (Pubitemid 43022686)
-
(2006)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.77
, Issue.1
, pp. 28-33
-
-
Jokinen, H.1
Kalska, H.2
Mantyla, R.3
Pohjasvaara, T.4
Ylikoski, R.5
Hietanen, M.6
Salonen, O.7
Kaste, M.8
Erkinjuntti, T.9
-
24
-
-
0028926408
-
Rolipram, a cyclic AMP-selective phosphodiesterase inhibitor, reduces neuronal damage following cerebral ischemia in the gerbil
-
7713141 10.1016/0014-2999(94)00694-3 1:CAS:528:DyaK2MXivVKlsL8%3D
-
H Kato T Araki Y Itoyama K Kogure 1995 Rolipram, a cyclic AMP-selective phosphodiesterase inhibitor, reduces neuronal damage following cerebral ischemia in the gerbil Eur J Pharmacol 272 107 110 7713141 10.1016/0014-2999(94)00694-3 1:CAS:528:DyaK2MXivVKlsL8%3D
-
(1995)
Eur J Pharmacol
, vol.272
, pp. 107-110
-
-
Kato, H.1
Araki, T.2
Itoyama, Y.3
Kogure, K.4
-
25
-
-
56749169284
-
Persistent behavioral impairments and neuroinflammation following global ischemia in the rat
-
19019197 10.1111/j.1460-9568.2008.06513.x
-
KD Langdon S Granter-Button D Corbett 2008 Persistent behavioral impairments and neuroinflammation following global ischemia in the rat Eur J Neurosci 28 2310 2318 19019197 10.1111/j.1460-9568.2008.06513.x
-
(2008)
Eur J Neurosci
, vol.28
, pp. 2310-2318
-
-
Langdon, K.D.1
Granter-Button, S.2
Corbett, D.3
-
26
-
-
70349150027
-
Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 (PDE4) inhibitor rolipram on behavior depend on cyclic AMP-response element binding protein (CREB)-mediated neurogenesis in the hippocampus
-
19516250 10.1038/npp.2009.66 1:CAS:528:DC%2BD1MXhtFajt7rP
-
YF Li Y Huang SL Amsdell L Xiao JM O'Donnell HT Zhang 2009 Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 (PDE4) inhibitor rolipram on behavior depend on cyclic AMP-response element binding protein (CREB)-mediated neurogenesis in the hippocampus Neuropsychopharmacology 34 2404 2419 19516250 10.1038/npp.2009.66 1:CAS:528:DC%2BD1MXhtFajt7rP
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 2404-2419
-
-
Li, Y.F.1
Huang, Y.2
Amsdell, S.L.3
Xiao, L.4
O'Donnell, J.M.5
Zhang, H.T.6
-
27
-
-
78650891913
-
Phosphodiesterase-4D knockout and RNAi-mediated knockdown enhance memory and increase hippocampal neurogenesis via increased cAMP signaling
-
21209202 10.1523/JNEUROSCI.5236-10.2011 1:CAS:528:DC%2BC3MXls1ygsg%3D%3D
-
YF Li YF Cheng Y Huang M Conti SP Wilson JM O'Donnell HT Zhang 2011 Phosphodiesterase-4D knockout and RNAi-mediated knockdown enhance memory and increase hippocampal neurogenesis via increased cAMP signaling J Neurosci 31 172 183 21209202 10.1523/JNEUROSCI.5236-10.2011 1:CAS:528:DC%2BC3MXls1ygsg%3D%3D
-
(2011)
J Neurosci
, vol.31
, pp. 172-183
-
-
Li, Y.F.1
Cheng, Y.F.2
Huang, Y.3
Conti, M.4
Wilson, S.P.5
O'Donnell, J.M.6
Zhang, H.T.7
-
28
-
-
66749127371
-
Effects of rolipram on learning and memory and the activity of PDE4 in hippocampus following the focal brain injury induced by ischemia-reperfusion in rats
-
1:CAS:528:DC%2BD1MXpvFWmsbw%3D
-
X Liu YF Cheng HT Zhang JP Xu 2008 Effects of rolipram on learning and memory and the activity of PDE4 in hippocampus following the focal brain injury induced by ischemia-reperfusion in rats Chin J Pathophysiol 24 1096 1100 1:CAS:528:DC%2BD1MXpvFWmsbw%3D
-
(2008)
Chin J Pathophysiol
, vol.24
, pp. 1096-1100
-
-
Liu, X.1
Cheng, Y.F.2
Zhang, H.T.3
Xu, J.P.4
-
29
-
-
35348906041
-
A novel phosphodiesterase type 4 inhibitor, HT-0712, enhances rehabilitation-dependent motor recovery and cortical reorganization after focal cortical ischemia
-
DOI 10.1177/1545968307305521
-
E MacDonald H Van der Lee D Pocock C Cole N Thomas PM VandenBerg R Bourtchouladze JA Kleim 2007 A novel phosphodiesterase type 4 inhibitor, HT-0712, enhances rehabilitation-dependent motor recovery and cortical reorganization after focal cortical ischemia Neurorehabil Neural Repair 21 486 496 17823313 10.1177/1545968307305521 (Pubitemid 47585201)
-
(2007)
Neurorehabilitation and Neural Repair
, vol.21
, Issue.6
, pp. 486-496
-
-
MacDonald, E.1
Van Der Lee, H.2
Pocock, D.3
Cole, C.4
Thomas, N.5
VandenBerg, P.M.6
Bourtchouladze, R.7
Kleim, J.A.8
-
30
-
-
30944445595
-
Subchronic rolipram delivery activates hippocampal CREB and Arc, enhances retention and slows down extinction of conditioned fear
-
DOI 10.1038/sj.npp.1300813, PII 1300813
-
B Monti C Berteotti A Contestabile 2006 Subchronic rolipram delivery activates hippocampal CREB and arc, enhances retention and slows down extinction of conditioned fear Neuropsychopharmacology 31 278 286 15988467 10.1038/sj.npp.1300813 1:CAS:528:DC%2BD28XkvFymsQ%3D%3D (Pubitemid 43113393)
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.2
, pp. 278-286
-
-
Monti, B.1
Berteotti, C.2
Contestabile, A.3
-
31
-
-
0021173996
-
Developments of a water-maze procedure for studying spatial learning in the rat
-
DOI 10.1016/0165-0270(84)90007-4
-
R Morris 1984 Developments of a water-maze procedure for studying spatial learning in the rat J Neurosci Methods 11 47 60 6471907 10.1016/0165-0270(84) 90007-4 1:STN:280:DyaL2c3ptl2lug%3D%3D (Pubitemid 14088970)
-
(1984)
Journal of Neuroscience Methods
, vol.11
, Issue.1
, pp. 47-60
-
-
Morris, R.1
-
32
-
-
0037008866
-
Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats
-
DOI 10.1016/S0306-4522(02)00207-5, PII S0306452202002075
-
A Nagakura N Takagi S Takeo 2002 Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats Neuroscience 113 519 528 12150772 10.1016/S0306-4522(02)00207-5 1:CAS:528:DC%2BD38XlvVelsbw%3D (Pubitemid 34874676)
-
(2002)
Neuroscience
, vol.113
, Issue.3
, pp. 519-528
-
-
Nagakura, A.1
Takagi, N.2
Takeo, S.3
-
33
-
-
0036968513
-
Effects of a phosphodiesterase IV inhibitor rolipram on microsphere embolism-induced defects in memory function and cerebral cyclic AMP signal transduction system in rats
-
DOI 10.1038/sj.bjp.0704629
-
A Nagakura M Niimura S Takeo 2002 Effects of a phosphodiesterase IV inhibitor rolipram on microsphere embolism-induced defects in memory function and cerebral cyclic AMP signal transduction system in rats Br J Pharmacol 135 1783 1793 11934820 10.1038/sj.bjp.0704629 1:CAS:528:DC%2BD38Xjt1aqt7k%3D (Pubitemid 36132709)
-
(2002)
British Journal of Pharmacology
, vol.135
, Issue.7
, pp. 1783-1793
-
-
Nagakura, A.1
Niimura, M.2
Takeo, S.3
-
34
-
-
0036581252
-
Regulation of Neurogenesis in Adult Mouse Hippocampus by cAMP and the cAMP Response Element-Binding Protein
-
S Nakagawa JE Kim R Lee JE Malberg J Chen C Steffen YJ Zhang EJ Nestler RS Duman 2002 Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein J Neurosci 22 3673 3682 11978843 1:CAS:528:DC%2BD38Xjs1Slsrw%3D (Pubitemid 37465772)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.9
, pp. 3673-3682
-
-
Nakagawa, S.1
Kim, J.-E.2
Lee, R.3
Malberg, J.E.4
Chen, J.5
Steffen, C.6
Zhang, Y.-J.7
Nestler, E.J.8
Duman, R.S.9
-
35
-
-
0031049849
-
Comparison of effects of global cerebral ischaemia on spatial learning in the standard and radial water maze: Relationship of hippocampal damage to performance
-
DOI 10.1016/S0166-4328(96)00167-2, PII S0166432896001672
-
A Nelson A Lebessi P Sowinski H Hodges 1997 Comparison of effects of global cerebral ischaemia on spatial learning in the standard and radial water maze: relationship of hippocampal damage to performance Behav Brain Res 85 93 115 9095344 10.1016/S0166-4328(96)00167-2 1:STN:280:DyaK2s3kvFCmug%3D%3D (Pubitemid 27116152)
-
(1997)
Behavioural Brain Research
, vol.85
, Issue.1
, pp. 93-115
-
-
Nelson, A.1
Lebessi, A.2
Sowinski, P.3
Hodges, H.4
-
36
-
-
0027207190
-
Effects of fetal hippocampal field grafts on ischaemic-induced deficits in spatial navigation in the water maze
-
DOI 10.1016/0306-4522(93)90384-R
-
CA Netto H Hodges JD Sinden E Le Peillet T Kershaw P Sowinski BS Meldrum JA Gray 1993 Effects of fetal hippocampal field grafts on ischaemic-induced deficits in spatial navigation in the water maze Neuroscience 54 69 92 8515847 10.1016/0306-4522(93)90384-R 1:STN:280:DyaK3s3psFGnsg%3D%3D (Pubitemid 23147089)
-
(1993)
Neuroscience
, vol.54
, Issue.1
, pp. 69-92
-
-
Netto, C.A.1
Hodges, H.2
Sinden, J.D.3
Le Peillet, E.4
Kershaw, T.5
Sowinski, P.6
Meldrum, B.S.7
Gray, J.A.8
-
37
-
-
0028355890
-
Global ischaemia: Hippocampal pathology and spatial deficits in the water maze
-
DOI 10.1016/0166-4328(94)90036-1
-
JA Nunn E LePeillet CA Netto H Hodges JA Gray BS Meldrum 1994 Global ischaemia: hippocampal pathology and spatial deficits in the water maze Behav Brain Res 62 41 54 7917032 10.1016/0166-4328(94)90036-1 1:STN:280: DyaK2M%2FgtVeitA%3D%3D (Pubitemid 24171559)
-
(1994)
Behavioural Brain Research
, vol.62
, Issue.1
, pp. 41-54
-
-
Nunn, J.A.1
LePeillet, E.2
Netto, C.A.3
Hodges, H.4
Gray, J.A.5
Meldrum, B.S.6
-
38
-
-
1342264246
-
Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4)
-
DOI 10.1016/j.tips.2004.01.003
-
JM O'Donnell HT Zhang 2004 Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4) Trends Pharmacol Sci 25 158 163 15019272 10.1016/j.tips.2004.01.003 (Pubitemid 38264507)
-
(2004)
Trends in Pharmacological Sciences
, vol.25
, Issue.3
, pp. 158-163
-
-
O'Donnell, J.M.1
Zhang, H.-T.2
-
39
-
-
0030846179
-
Sequence of neuronal responses assessed by immunohistochemistry in the newborn rat brain after hypoxia-ischemia
-
DOI 10.1016/S0002-9378(97)70139-X
-
A Ota T Ikeda T Ikenoue K Toshimori 1997 Sequence of neuronal responses assessed by immunohistochemistry in the newborn rat brain after hypoxia-ischemia Am J Obstet Gynecol 177 519 526 9322617 10.1016/S0002-9378(97)70139-X 1:STN:280:DyaK2svmtl2itA%3D%3D (Pubitemid 27413762)
-
(1997)
American Journal of Obstetrics and Gynecology
, vol.177
, Issue.3
, pp. 519-526
-
-
Ota, A.1
Ikeda, T.2
Ikenoue, T.3
Toshimori, K.4
-
40
-
-
0034468228
-
3H]rolipram binding autoradiography: Comparison with monkey and rat brain
-
DOI 10.1016/S0891-0618(00)00097-1, PII S0891061800000971
-
S Perez-Torres X Miro JM Palacios R Cortes P Puigdomenech G Mengod 2000 Phosphodiesterase type 4 isozymes expression in human brain examined by in situ hybridization histochemistry and [3H]rolipram binding autoradiography. Comparison with monkey and rat brain J Chem Neuroanat 20 349 374 11207431 10.1016/S0891-0618(00)00097-1 1:CAS:528:DC%2BD3MXht1Oqt7k%3D (Pubitemid 32162892)
-
(2000)
Journal of Chemical Neuroanatomy
, vol.20
, Issue.3-4
, pp. 349-374
-
-
Perez-Torres, S.1
Miro, X.2
Palacios, J.M.3
Cortes, R.4
Puigdomenech, P.5
Mengod, G.6
-
41
-
-
0018347695
-
A new model of bilateral hemispheric ischemia in the unanesthetized rat
-
WA Pulsinelli JB Brierley 1979 A new model of bilateral hemispheric ischemia in the unanesthetized rat Stroke 10 267 272 37614 1:STN:280: DyaE1M3is1amtQ%3D%3D (Pubitemid 9141527)
-
(1979)
Stroke
, vol.10
, Issue.3
, pp. 267-272
-
-
Pulsinelli, W.A.1
Brierley, J.B.2
-
42
-
-
0020067965
-
Temporal profile of neuronal damage in a model of transient forebrain ischemia
-
WA Pulsinelli JB Brierley F Plum 1982 Temporal profile of neuronal damage in a model of transient forebrain ischemia Ann Neurol 11 491 498 7103425 10.1002/ana.410110509 1:STN:280:DyaL383lsFaisw%3D%3D (Pubitemid 12158810)
-
(1982)
Annals of Neurology
, vol.11
, Issue.5
, pp. 491-498
-
-
Pulsinelli, W.A.1
Brierley, J.B.2
Plum, F.3
-
43
-
-
32644461812
-
Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action
-
DOI 10.1016/j.nlm.2005.09.002, PII S1074742705000869
-
K Rutten J Prickaerts A Blokland 2006 Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action Neurobiol Learn Mem 85 132 138 16242977 10.1016/j.nlm.2005.09.002 1:CAS:528:DC%2BD28XhsF2nt7o%3D (Pubitemid 43247839)
-
(2006)
Neurobiology of Learning and Memory
, vol.85
, Issue.2
, pp. 132-138
-
-
Rutten, K.1
Prickaerts, J.2
Blokland, A.3
-
44
-
-
34247629557
-
The phosphodiesterase inhibitor rolipram promotes survival of newborn hippocampal neurons after ischemia
-
DOI 10.1161/STROKEAHA.106.476754, PII 0000767020070500000040
-
T Sasaki K Kitagawa E Omura-Matsuoka K Todo Y Terasaki S Sugiura, et al. 2007 The phosphodiesterase inhibitor rolipram promotes survival of newborn hippocampal neurons after ischemia Stroke 38 1597 1605 17379823 10.1161/STROKEAHA.106.476754 1:CAS:528:DC%2BD2sXktlSnu7c%3D (Pubitemid 46684180)
-
(2007)
Stroke
, vol.38
, Issue.5
, pp. 1597-1605
-
-
Sasaki, T.1
Kitagawa, K.2
Omura-Matsuoka, E.3
Todo, K.4
Terasaki, Y.5
Sugiura, S.6
Hatazawa, J.7
Yagita, Y.8
Hori, M.9
-
45
-
-
0026726950
-
Effects of ischemia duration on neurological outcome, CA1 histopathology and nonmatching to sample learning in monkeys
-
1412584 1:STN:280:DyaK3s%2FjtF2qsQ%3D%3D
-
MS Scheller MR Grafe MH Zornow JH Fleischer 1992 Effects of ischemia duration on neurological outcome, CA1 histopathology and nonmatching to sample learning in monkeys Stroke 23 1471 1478 1412584 1:STN:280:DyaK3s%2FjtF2qsQ%3D%3D
-
(1992)
Stroke
, vol.23
, pp. 1471-1478
-
-
Scheller, M.S.1
Grafe, M.R.2
Zornow, M.H.3
Fleischer, J.H.4
-
46
-
-
0034009080
-
Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions
-
DOI 10.1016/S0955-0674(99)00073-3
-
SH Soderling JA Beavo 2000 Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions Curr Opin Cell Biol 12 174 179 10712916 10.1016/S0955-0674(99)00073-3 1:CAS:528:DC%2BD3cXitVantLs%3D (Pubitemid 30142563)
-
(2000)
Current Opinion in Cell Biology
, vol.12
, Issue.2
, pp. 174-179
-
-
Soderling, S.H.1
Beavo, J.A.2
-
47
-
-
0035666581
-
Chronic cerebral hypoperfusion in the rat enhances age-related deficits in spatial memory
-
DOI 10.1007/s007020100019
-
M Sopala W Danysz 2001 Chronic cerebral hypoperfusion in the rat enhances age-related deficits in spatial memory J Neural Transm 108 1445 1456 11810407 10.1007/s007020100019 1:STN:280:DC%2BD38%2Fotlaqsg%3D%3D (Pubitemid 34020448)
-
(2001)
Journal of Neural Transmission
, vol.108
, Issue.12
, pp. 1445-1456
-
-
Sopala, M.1
Danysz, W.2
-
48
-
-
0037293506
-
A possible mechanism for improvement by a cognition-enhancer nefiracetam of spatial memory function and cAMP-mediated signal transduction system in sustained cerebral ischaemia in rats
-
DOI 10.1038/sj.bjp.0705096
-
S Takeo M Niimura K Miyake-Takagi A Nagakura T Fukatsu T Ando N Takagi K Tanonaka J Hara 2003 A possible mechanism for improvement by a cognition-enhancer nefiracetam of spatial memory function and cAMP-mediated signal transduction system in sustained cerebral ischaemia in rats Br J Pharmacol 138 642 654 12598418 10.1038/sj.bjp.0705096 1:CAS:528: DC%2BD3sXitlCktr8%3D (Pubitemid 36315312)
-
(2003)
British Journal of Pharmacology
, vol.138
, Issue.4
, pp. 642-654
-
-
Takeo, S.1
Niimura, M.2
Miyake-Takagi, K.3
Nagakura, A.4
Fukatsu, T.5
Ando, T.6
Takagi, N.7
Tanonaka, K.8
Hara, J.9
-
50
-
-
0034576039
-
Phosphorylated cAMP response element-binding protein as a molecular marker of memory processing in rat hippocampus: Effect of novelty
-
11090612 1:STN:280:DC%2BD3M7gs1KqtA%3D%3D
-
H Viola M Furman LA Izquierdo M Alonso DM Barros MM de Souza I Izquierdo JH Medina 2000 Phosphorylated cAMP response element-binding protein as a molecular marker of memory processing in rat hippocampus: effect of novelty J Neurosci 20 RC112 11090612 1:STN:280:DC%2BD3M7gs1KqtA%3D%3D
-
(2000)
J Neurosci
, vol.20
, pp. 112
-
-
Viola, H.1
Furman, M.2
Izquierdo, L.A.3
Alonso, M.4
Barros, D.M.5
De Souza, M.M.6
Izquierdo, I.7
Medina, J.H.8
-
51
-
-
0036842355
-
Inhibition of human phosphodiesterase 4A expressed in yeast cell GL62 by theophylline, rolipram, and acetamide-45
-
K Wang JQ Chen Z Chen JC Chen 2002 Inhibition of human phosphodiesterase 4A expressed in yeast cell GL62 by theophylline, rolipram, and acetamide-45 Acta Pharmacol Sin 23 1013 1017 12421478 1:CAS:528:DC%2BD38Xos1Cktbw%3D (Pubitemid 35285185)
-
(2002)
Acta Pharmacologica Sinica
, vol.23
, Issue.11
, pp. 1013-1017
-
-
Wang, K.1
Chen, J.-Q.2
Chen, Z.3
Chen, J.-C.4
-
52
-
-
60549116497
-
Phosphodiesterase 4D gene polymorphism is associated with ischaemic and haemorrhagic stroke
-
10.1042/CS20080162 1:CAS:528:DC%2BD1MXlsFKntw%3D%3D
-
H Xue H Wang X Song W Li K Sun W Zhang X Wang Y Wang R Hui 2009 Phosphodiesterase 4D gene polymorphism is associated with ischaemic and haemorrhagic stroke Clin Sci (Lond) 116 335 340 10.1042/CS20080162 1:CAS:528:DC%2BD1MXlsFKntw%3D%3D
-
(2009)
Clin Sci (Lond)
, vol.116
, pp. 335-340
-
-
Xue, H.1
Wang, H.2
Song, X.3
Li, W.4
Sun, K.5
Zhang, W.6
Wang, X.7
Wang, Y.8
Hui, R.9
-
53
-
-
0029923241
-
Diminished noradrenergic stimulation reduces the activity of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase in rat cerebral cortex
-
8780016 10.1046/j.1471-4159.1996.66051894.x 1:CAS:528:DyaK28XisVSku70%3D
-
Y Ye JM O'Donnell 1996 Diminished noradrenergic stimulation reduces the activity of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase in rat cerebral cortex J Neurochem 66 1894 1902 8780016 10.1046/j.1471-4159.1996. 66051894.x 1:CAS:528:DyaK28XisVSku70%3D
-
(1996)
J Neurochem
, vol.66
, pp. 1894-1902
-
-
Ye, Y.1
O'Donnell, J.M.2
-
54
-
-
33747173366
-
Polymorphisms of the phosphodiesterase 4D, cAMP-specific (PDE4D) gene and risk of ischemic stroke: A prospective, nested case-control evaluation
-
DOI 10.1161/01.STR.0000230608.56048.38, PII 0000767020060800000018
-
RY Zee VH Brophy S Cheng HH Hegener HA Erlich PM Ridker 2006 Polymorphisms of the phosphodiesterase 4D, cAMP-specific (PDE4D) gene and risk of ischemic stroke: a prospective, nested case-control evaluation Stroke 37 2012 2017 16825591 10.1161/01.STR.0000230608.56048.38 1:CAS:528:DC%2BD28XmvFaksro%3D (Pubitemid 44309896)
-
(2006)
Stroke
, vol.37
, Issue.8
, pp. 2012-2017
-
-
Zee, R.Y.L.1
Brophy, V.H.2
Cheng, S.3
Hegener, H.H.4
Erlich, H.A.5
Ridker, P.M.6
-
55
-
-
67650569455
-
Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs
-
19442182 10.2174/138161209788168092 1:CAS:528:DC%2BD1MXmtValt7k%3D
-
HT Zhang 2009 Cyclic AMP-specific phosphodiesterase-4 as a target for the development of antidepressant drugs Curr Pharm Des 15 1688 1698 19442182 10.2174/138161209788168092 1:CAS:528:DC%2BD1MXmtValt7k%3D
-
(2009)
Curr Pharm des
, vol.15
, pp. 1688-1698
-
-
Zhang, H.T.1
-
56
-
-
77749309302
-
Phosphodiesterase targets for cognitive dysfunction and schizophrenia-A New York Academy of Sciences Meeting
-
20191432
-
HT Zhang 2010 Phosphodiesterase targets for cognitive dysfunction and schizophrenia-a New York Academy of Sciences Meeting IDrugs 13 166 168 20191432
-
(2010)
IDrugs
, vol.13
, pp. 166-168
-
-
Zhang, H.T.1
-
57
-
-
0033922848
-
Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats
-
DOI 10.1007/s002130000414
-
HT Zhang JM O'Donnell 2000 Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats Psychopharmacology (Berl) 150 311 316 10.1007/s002130000414 1:CAS:528: DC%2BD3cXltFGisLw%3D (Pubitemid 30447851)
-
(2000)
Psychopharmacology
, vol.150
, Issue.3
, pp. 311-316
-
-
Zhang, H.-T.1
O'Donnell, J.M.2
-
58
-
-
0034051217
-
Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism
-
DOI 10.1016/S0893-133X(00)00108-1, PII S0893133X00001081
-
HT Zhang AM Crissman NR Dorairaj LJ Chandler JM O'Donnell 2000 Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism Neuropsychopharmacology 23 198 204 10882846 10.1016/S0893-133X(00)00108-1 1:CAS:528:DC%2BD3cXksFGjtb4%3D (Pubitemid 30406904)
-
(2000)
Neuropsychopharmacology
, vol.23
, Issue.2
, pp. 198-204
-
-
Zhang, H.-T.1
Crissman, A.M.2
Dorairaj, N.R.3
Chandler, L.J.4
O'Donnell, J.M.5
-
59
-
-
0036790883
-
Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme
-
12377395 1:CAS:528:DC%2BD38Xns1Sjt7c%3D
-
HT Zhang Y Huang SL Jin SA Frith N Suvarna M Conti JM O'Donnell 2002 Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme Neuropsychopharmacology 27 587 595 12377395 1:CAS:528:DC%2BD38Xns1Sjt7c%3D
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 587-595
-
-
Zhang, H.T.1
Huang, Y.2
Jin, S.L.3
Frith, S.A.4
Suvarna, N.5
Conti, M.6
O'Donnell, J.M.7
-
60
-
-
3242758203
-
Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus
-
DOI 10.1038/sj.npp.1300440
-
HT Zhang Y Zhao Y Huang NR Dorairaj LJ Chandler JM O'Donnell 2004 Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus Neuropsychopharmacology 29 1432 1439 15114341 10.1038/sj.npp.1300440 1:CAS:528:DC%2BD2cXlvVSjsbw%3D (Pubitemid 38982235)
-
(2004)
Neuropsychopharmacology
, vol.29
, Issue.8
, pp. 1432-1439
-
-
Zhang, H.-T.1
Zhao, Y.2
Huang, Y.3
Dorairaj, N.R.4
Chandler, L.J.5
O'Donnell, J.M.6
-
61
-
-
18744416953
-
Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats
-
DOI 10.1007/s00213-004-2085-2
-
HT Zhang Y Huang NU Suvarna C Deng AM Crissman AT Hopper M De Vivo GM Rose JM O'Donnell 2005 Effects of the novel PDE4 inhibitors MEM1018 and MEM1091 on memory in the radial-arm maze and inhibitory avoidance tests in rats Psychopharmacol Berl 179 613 619 10.1007/s00213-004-2085-2 1:CAS:528: DC%2BD2MXjslOrs7k%3D (Pubitemid 40674762)
-
(2005)
Psychopharmacology
, vol.179
, Issue.3
, pp. 613-619
-
-
Zhang, H.-T.1
Huang, Y.2
Suvarna, N.U.3
Deng, C.4
Crissman, A.M.5
Hopper, A.T.6
De Vivo, M.7
Rose, G.M.8
O'Donnell, J.M.9
|