Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 66 A, Issue 3, 2011, Pages 332-340

  Yarasheski, Kevin E ^a   Scherzer, Rebecca ^b,c   Kotier, Donald P ^d   Dobs, Adrian S ^e   Tien, Phyllis C ^b,c   Lewis, Cora E ^f   Kronmal, Richard A ^g   Heymsfield, Steven B ^h   Bacchetti, Peter ^c   Grunfeld, Carl ^b,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f University of Alabama at Birmingham   (United States)

^g UNIVERSITY OF WASHINGTON   (United States)

^h PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Body composition; Fat redistribution; Lipoatrophy; Sarcopenia

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS;

ADULT; AGE; AGED; AGING; ARTICLE; COMPARATIVE STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN SIZE; PATHOLOGY; PHYSIOLOGY; SKELETAL MUSCLE;

ADULT; AGE FACTORS; AGED; AGING; FEMALE; HIV INFECTIONS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MUSCLE, SKELETAL; ORGAN SIZE;

EID: 79955084432     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glq228     Document Type: Article

References (47)

1. Palella FJ Jr., Baker RK, Moorman AC, et al. Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study. J Acquir Immune Defic Syndr. 2006;43: 27-34. (Pubitemid 44306484)
2. Cockerham L, Scherzer R, Zolopa A, et al. Association of HIV infection, demographic and cardiovascular risk factors with all-cause mortality in the recent HAART era. J Acquir Immune Defic Syndr. 2010;53:102-106.
3. Deeks SG. Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy. Top HIV Med. 2009;17:118-123.
4. Smit E, Skolasky RL, Dobs AS, et al. Changes in the incidence and predictors of wasting syndrome related to human immunodeficiency virus infection, 1987-1999. Am J Epidemiol. 2002;156:211-218. (Pubitemid 34810474)
5. Evans WJ. Skeletal muscle loss: cachexia, sarcopenia, and inactivity. Am J Clin Nutr. 2010;91:1123S-1127S.
6. Granfeld C, Feingold KR. Metabolic disturbances and wasting in the acquired immunodeficiency syndrome. N Engl J Med. 1992;327:329-337.
7. Tang AM, Jacobson DL, Spiegelman D, Knox TA, Wanke C. Increasing risk of 5% or greater unintentional weight loss in a cohort of HIV-infected patients, 1995 to 2003. J Acquir Immune Defic Syndr. 2005; 40:70-76. (Pubitemid 41233208)
8. Szulc P, Munoz F, Marchand F, Chapurlat R, Delmas PD. Rapid loss of appendicular skeletal muscle mass is associated with higher all-cause mortality in older men: the prospective MINOS study. Am J Clin Nutr. 2010;91:1227-1236.
9. Li C, Ford ES, Zhao G, Balluz LS, Giles WH. Estimates of body composition with dual-energy X-ray absorptiometry in adults. Am J Clin Nutr. 2009;90:1457-1465.
10. Hughes VA, Frontera WR, Roubenoff R, Evans WJ, Singh MA. Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr. 2002;76:473-481. (Pubitemid 34804075)
11. Goodpaster BH, Park SW, Harris TB, et al. The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci. 2006;61: 1059-1064. (Pubitemid 44727214)
12. Tsekes G, Chrysos G, Douskas G, et al. Body composition changes in protease inhibitor-naive HIV-infected patients treated with two nucleoside reverse transcriptase inhibitors. HIV Med. 2002;3:85-90. (Pubitemid 34567578)
13. Bolland MJ, Grey AB, Home AM, et al. Bone mineral density remains stable in HAART-treated HIV-infected men over 2 years. Clin Endocrinol (Oxf). 2007;67:270-275. (Pubitemid 47076305)
14. McDermott AY, Terrin N, Wanke C, Skinner S, Tchetgen E, Shevitz AH. CD4+ cell count, viral load, and highly active antiretroviral therapy use are independent predictors of body composition alterations in HIV-infected adults: a longitudinal study. Clin Infect Dis. 2005;41:1662-1670. (Pubitemid 41691607)
15. Degris E, Delpierre C, Sommet A, et al. Longitudinal study of body composition of 101 HIV men with lipodystrophy: DXA criteria for lipodystrophy evolution. J Clin Densitom. 2010;13(2):237-244.
16. Thomas DM, Das SK, Levine JA, et al. New fat free mass - fat mass model for use in physiological energy balance equations. Nutr Metab. 2010; In press.
17. Heymsfield SB, Scherzer R, Pietrobelli A, Lewis CE, Grunfeld C. Body mass index as a phenotypic expression of adiposity: quantitative contribution of muscularity in a population-based sample. Int J Obes (Lond). 2009;33:1363-1373.
18. Westerterp KR, Meijer GA, Kester AD, Wouters L, ten Hoor F Fat-free mass as a function of fat mass and habitual activity level. Int JSportsMed. 1992;13:163-166.
19. Bacchetti P, Gripshover B, Grunfeld C, et al. Fat distribution in men with HIV infection. J Acquir Immune Defic Syndr. 2005;40:121-131. (Pubitemid 41395709)
20. Bacchetti P, Cofrancesco J, Heymsfield S, et al. Fat distribution in women with HIV infection. J Acquir Immune Defic Syndr. 2006;42: 562-571.
21. Grunfeld C, Saag M, Cofrancesco J, et al. Regional adipose tissue measured by MRI over five years in HIV-infected and control subjects indicates persistence of HIV-associated lipoatrophy. AIDS. 2010;24: 1717-1726.
22. Tien PC, Benson C, Zolopa AR, Sidney S, Osmond D, Grunfeld C. The study of fat redistribution and metabolic change in HIV infection (FRAM): methods, design, and sample characteristics. Am J Epidemiol. 2006;163:860-869.
23. Friedman GD, Cutter GR, Donahue RP, et al. CARDIA: study design, recruitment, and some characteristics of the examined subjects. J Clin Epidemiol. 1988;41:1105-1116. (Pubitemid 19039041)
24. Hill JO, Sidney S, Lewis CE, Tolan K, Scherzinger AL, Stamm ER. Racial differences in amounts of visceral adipose tissue in young adults: the CARDIA (Coronary Artery Risk Development in Young Adults) study. Am J Clin Nutr. 1999;69:381-387. (Pubitemid 29104556)
25. Choi A, Scherzer R, Bacchetti P, et al. Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons. Am J Kidney Dis. 2010;56(5):872-882.
26. Gallagher D, Belmonte D, Deurenberg P, et al. Organ-tissue mass measurement allows modeling of REE and metabolically active tissue mass. Am J Physiol. 1998;275:E249-E258.
27. Scherzer R, Shen W, Heymsfield SB, et al. Intermuscular adipose tissue and metabolic associations in HIV infection. Obesity (Silver Spring). 2010; In press.
28. Frisancho AR, Flegel PN. Elbow breadth as a measure of frame size for US males and females. Am J Clin Nutr. 1983;37:311-314. (Pubitemid 13130707)
29. Searle SR, Speed FM, Milliken GA. Populations marginal means in the linear model: an alternative to least squares means. Am Stat. 1980; 34:216-221.
30. Huber P. The behavior of maximum likelihood estimates under nonstandard conditions. In Proceedings of the Fifth Berkeley Symposium on Mathematical Statistics and Probability; 1967; Berkeley, CA: University of California Press. 221-223.
31. White H. A heteroskedasticity-consistent covariance matrix estimator and a direct test for heteroskedasticity. Econometrica. 1980;48:817-830.
32. Hastie T, Tibshirani R. Generalized Additive Models. New York: Chapman & Hall; 1990.
33. Schafer JL. Multiple imputation: a primer. Stat Methods Med Res. 1999;8:3-15. (Pubitemid 29222784)
34. Robins JM, Finkelstein DM. Correcting for noncompliance and dependent censoring in an AIDS Clinical Trial with inverse probability of censoring weighted (IPCW) log-rank tests. Biometrics. 2000;56:779-788.
35. Mulligan K, Tai VW, Schambelan M. Cross-sectional and longitudinal evaluation of body composition in men with HIV infection. J Acquir Immune Defic Syndr Hum Retroviral. 1997;15:43-48.
36. Kotier DP, Wang J, Pierson RN. Body composition studies in patients with the acquired immunodeficiency syndrome. Am J Clin Nutr. 1985;42:1255-1265. (Pubitemid 16166024)
37. Grinspoon S, Corcoran C, Miller K, et al. Body composition and endocrine function in women with acquired immunodeficiency syndrome wasting. J Clin Endocrinol Metab. 1997;82:1332-1337. (Pubitemid 27200397)
38. Yarasheski KE, Zachwieja JJ, Gischler J, Crowley J, Horgan MM, Powderly WG. Increased plasma gln and Leu Ra and inappropriately low muscle protein synthesis rate in AIDS wasting. Am J Physiol. 1998;275:E577-E583.
39. Yarasheski KE, Smith SR, Powderly WG. Reducing plasma HIV RNA improves muscle amino acid metabolism. Am J Physiol Endocrinol Metab. 2005;288:E278-E284. (Pubitemid 40023817)
40. Hong-Brown LQ, Pruznak AM, Frost RA, Vary TC, Lang CH. Indinavir alters regulators of protein anabolism and catabolism in skeletal muscle. Am J Physiol Endocrinol Metab. 2005;289:E382-E390. (Pubitemid 41192693)
41. Chantry CJ, Cervia JS, Hughes MD, et al. Predictors of growth and body composition in HIV-infected children beginning or changing antiretroviral therapy. HIV Med. 2010.
42. Note R, Maisonneuve C, Letteron P, et al. Mitochondrial and metabolic effects of nucleoside reverse transcriptase inhibitors (NRTIs) in mice receiving one of five single- and three dual-NRTI treatments. Antimicrob Agents Chemother. 2003;47:3384-3392. (Pubitemid 37345694)
43. Divi RL, Leonard SL, Walker BL, et al. Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age. Toxicol Sci. 2007;99:203-213. (Pubitemid 47250380)
44. Fleischman A, Johnsen S, Systrom DM, et al. Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults. Am J Physiol Endocrinol Metab. 2007;292:E1666-E1673. (Pubitemid 47084702)
45. Newman AB, Kupelian V, Visser M, et al. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci. 2006;61:72-77. (Pubitemid 43227803)
46. Swallow EB, Reyes D, Hopkinson NS, et al. Quadriceps strength predicts mortality in patients with moderate to severe chronic obstructive pulmonary disease. Thorax. 2007;62:115-120.
47. Desquilbet L, Margolick JB, Fried LP, et al. Relationship between a frailty-related phenotype and progressive deterioration of the immune system in HIV-infected men. J Acquir Immune Defic Syndr. 2009;50: 299-306.