Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 3, 2011, Pages

  Kang, Kyu Tae ^a   Sullivan, Jennifer C ^a   Spradley, Frank T ^a   d'Uscio, Livius V ^b   Katusic, Zvonimir S ^b   Pollock, Jennifer S ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Hypertension; Nitric oxide synthase; Small mesenteric arteries; Triple therapy

Indexed keywords

ANGIOTENSIN II; CYCLIC GMP; DIHYDROBIOPTERIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HYDRALAZINE; HYDROCHLOROTHIAZIDE; NITRIC OXIDE; RESERPINE; SERINE; TETRAHYDROBIOPTERIN; THREONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD PRESSURE REGULATION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HYPERTENSION; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE;

ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BIOPTERIN; CYCLIC GMP; GTP CYCLOHYDROLASE; HYDRALAZINE; HYDROCHLOROTHIAZIDE; HYPERTENSION; MALE; MESENTERIC ARTERIES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, SPRAGUE-DAWLEY; RESERPINE; SIGNAL TRANSDUCTION;

EID: 79955070997     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00393.2010     Document Type: Article

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