Narrowing a region on rat chromosome 13 that protects against hypertension in Dahl SS-13 BN congenic strains

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 4, 2011, Pages

  Moreno, Carol ^a   Williams, Jan M ^b   Lu, Limin ^a   Liang, Mingyu ^a   Lazar, Jozef ^a   Jacob, Howard J ^a   Cowley, Allen W ^a   Roman, Richard J ^b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Dahl S rats; Glomerulus; Kidney; Proteinuria; Renal disease

Indexed keywords

PROTEIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BROWN NORWAY RAT; CHROMOSOME 13; CONGENIC STRAIN; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; DIET; GENE EXPRESSION; HIGH SALT DIET; HYPERTENSION; KIDNEY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEINURIA; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TELEMETRY;

ANIMALS; ANIMALS, CONGENIC; BASE SEQUENCE; CHROMOSOMES, MAMMALIAN; GENETIC LOCI; HYPERTENSION; KIDNEY; MALE; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINURIA; RATS; RATS, INBRED DAHL; SODIUM CHLORIDE, DIETARY;

EID: 79955067680     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01026.2010     Document Type: Article

References (21)

1. Akiyama K, Morita H, Suetsugu S, Kuraba S, Numata Y, Yamamoto Y, Inui K, Ideura T, Wakisaka N, Nakano K, Oniki H, Takenawa T, Matsuyama M, Yoshimura A. Actin-related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats. Mamm Genome 19: 41-50, 2008.
2. Burre J, Zimmermann H, Volknandt W. Identification and characterization of SV31, a novel synaptic vesicle membrane protein and potential transporter. J Neurochem 103: 276-287, 2007.
3. Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC. Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Transgenic Res 20: 29-45, 2011.
4. Cowley AW Jr, Roman RJ, Kaldunski ML, Dumas P, Dickhout JG, Greene AS, Jacob HJ. Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension 37: 456-461, 2001.
5. Ewing B, Hillier L, Wendl MC, Green P. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res 8: 175-185, 1998.
6. Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, Kalloway S, Weiler H, Menoret S, Anegon I, Davis GD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jacob HJ, Buelow R. Knockout rats via embryo microinjection of zinc-finger nucleases. Science 325: 433, 2009.
7. Jiang J, Stec DE, Drummond H, Simon JS, Koike G, Jacob HJ, Roman RJ. Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats. Hypertension 29: 619-627, 1997.
8. Kent WJ. BLAT-the BLAST-like alignment tool. Genome Res 12: 656-664, 2002.
9. Krushkal J, Xiong M, Ferrell R, Sing CF, Turner ST, Boerwinkle E. Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation. Hum Mol Genet 7: 1379-1383, 1998.
10. Moreno C, Kaldunski ML, Wang T, Roman RJ, Greene AS, Lazar J, Jacob HJ, Cowley AW Jr. Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat. Physiol Genomics 31: 228-235, 2007.
11. Moreno C, Kennedy K, Andrae JW, Jacob HJ. Genome-wide scanning with SSLPs in the rat. Methods Mol Med 108: 131-138, 2005.
12. Ng PC, Henikoff S. Predicting deleterious amino acid substitutions. Genome Res 11: 863-874, 2001.
13. Ramensky V, Bork P, Sunyaev S. Human nonsynonymous SNPs: server and survey. Nucleic Acids Res 30: 3894-3900, 2002.
14. Rapp JP, Wang SM, Dene H. A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure. Science 243: 542-544, 1989.
15. Rice T, Rankinen T, Province MA, Chagnon YC, Perusse L, Borecki IB, Bouchard C, Rao DC. Genome-wide linkage analysis of systolic and diastolic blood pressure: the Quebec Family Study. Circulation 102: 1956-1963, 2000.
16. Rozen S, Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132: 365-386, 2000.
17. Schlick NE, Jensen-Seaman MI, Orlebeke K, Kwitek AE, Jacob HJ, Lazar J. Sequence analysis of the complete mitochondrial DNA in 10 commonly used inbred rat strains. Am J Physiol Cell Physiol 291: C1183-C1192, 2006.
18. Schmitz U, Thommes K, Beier I, Dusing R, Vetter H. Identification of Nck interacting proteins in vascular smooth muscle cells. Clin Exp Hypertens 26: 267-275, 2004.
19. Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E, Greenwood TA, Hipolito M, Koller DL, Lawson WB, Liu C, Lohoff F, McInnis MG, McMahon FJ, Mirel DB, Murray SS, Nievergelt C, Nurnberger J, Nwulia EA, Paschall J, Potash JB, Rice J, Schulze TG, Scheftner W, Panganiban C, Zaitlen N, Zandi PP, Zollner S, Schork NJ, Kelsoe JR. Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry 14: 755-763, 2009.
20. St Lezin EM, Pravenec M, Wong AL, Liu W, Wang N, Lu S, Jacob HJ, Roman RJ, Stec DE, Wang JM, Reid IA, Kurtz TW. Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats. J Clin Invest 97: 522-527, 1996.
21. Zhang QY, Dene H, Deng AY, Garrett MR, Jacob HJ, Rapp JP. Interval mapping and congenic strains for a blood pressure QTL on rat chromosome 13. Mamm Genome 8: 636-641, 1997.