Severe hemolytic crisis after ceftriaxone administration

Pediatric Emergency Care

Volumn 27, Issue 4, 2011, Pages 322-323

  Goyal, Monika ^a   Donoghue, Aaron ^a   Schwab, Sandra ^a   Hasbrouck, Nicole ^a   Khojasteh, Soreena ^a   Osterhoudt, Kevin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

adverse reaction; ceftriaxone; hemolysis; Sickle cell

Indexed keywords

BILIRUBIN; CEFTRIAXONE; DRUG ANTIBODY; HAPTOGLOBIN; HEMOGLOBIN; LACTATE DEHYDROGENASE; MYOGLOBIN;

ACIDEMIA; ACUTE CHEST SYNDROME; ACUTE KIDNEY FAILURE; ANEMIA; ANTIBIOTIC THERAPY; ANTIBODY RESPONSE; ARTICLE; BACTEREMIA; BILIRUBIN BLOOD LEVEL; BLOOD GAS ANALYSIS; CASE REPORT; CHILD; COOMBS TEST; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; ENDOTRACHEAL INTUBATION; ERYTHROCYTE CONCENTRATE; FECES INCONTINENCE; FEMALE; FEVER; HEMATURIA; HEMODIALYSIS; HEMOGLOBIN BLOOD LEVEL; HEMOGLOBINURIA; HEMOLYSIS; HUMAN; HYPOTENSION; LABORATORY TEST; LACTATE DEHYDROGENASE BLOOD LEVEL; LUNG INFILTRATE; MALE; PALLOR; PLASMAPHERESIS; PLEURA EFFUSION; POINT OF CARE TESTING; PRESCHOOL CHILD; RESPIRATORY FAILURE; SCHOOL CHILD; SICKLE CELL ANEMIA; TACHYCARDIA; THORAX RADIOGRAPHY; URINALYSIS; URINE INCONTINENCE;

ANTI-BACTERIAL AGENTS; CEFTRIAXONE; CHILD; CHILD, PRESCHOOL; FEMALE; HEMOLYSIS; HUMANS; MALE; SEVERITY OF ILLNESS INDEX;

EID: 79955066095     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/PEC.0b013e3182131fa8     Document Type: Article

References (3)

1. Bernini JC, Mustafa MM, Sutor LJ, et al. Fatal hemolysis induced by ceftriaxone in a child with sickle cell anemia. J Pediatr. 1995; 126(5 pt 1):813-815.
2. Hemolysis from ceftriaxone. Med Lett Drugs Ther. 2002;44(1144): 100-101.
3. Quillen K, Lane C, Hu E, et al. Prevalence of ceftriaxone-induced red blood cell antibodies in pediatric patients with sickle cell disease and human immunodeficiency virus infection. Pediatr Infect Dis J. 2008;27(4):357-358. (Pubitemid 351483073)