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Volumn 22, Issue 3, 2011, Pages 206-210

Functionality of fondaparinux (pentasaccharide) depends on clinical antithrombin levels

Author keywords

Antifactor Xa activity; antithrombin; antithrombotic activity; fondaparinux; heparin pentasaccharide

Indexed keywords

ANTIFACTOR XA; ANTITHROMBIN; FONDAPARINUX; PROTEIN; UNCLASSIFIED DRUG;

EID: 79955059072     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e328343f859     Document Type: Article
Times cited : (6)

References (23)
  • 5
    • 0025908340 scopus 로고
    • Chemical synthesis of glycosaminoglycans: New approaches to antithrombotic drugs
    • Petitou M, Lormeau JC, Choay J. Chemical synthesis of glycosaminoglycans: new approaches to antithrombotic drugs. Nature 1991; 350 (Suppl):30-33.
    • (1991) Nature , vol.350 , Issue.1 , pp. 30-33
    • Petitou, M.1    Lormeau, J.C.2    Choay, J.3
  • 6
    • 33748233635 scopus 로고
    • The unique antithrombin III binding domain of heparin: A lead to new synthetic antithrombotics
    • van Boeckel CAA, Petitou M. The unique antithrombin III binding domain of heparin: a lead to new synthetic antithrombotics. Angew Chem Int Ed Engl 1993; 32:1671-1690.
    • (1993) Angew. Chem. Int. Ed. Engl. , vol.32 , pp. 1671-1690
    • Van Boeckel, C.A.A.1    Petitou, M.2
  • 8
    • 0029563321 scopus 로고
    • The effect of the synthetic pentasaccharide SR 90107/ORG 31540 on thrombin generation ex vivo is uniquely due to ATIII-mediated neutralization of factor Xa
    • Lormeau JC, Herault JP. The effect of the synthetic pentasaccharide SR 90107/ORG 31540 on thrombin generation ex vivo is uniquely due to ATIIImediated neutralization of factor Xa. Thromb Haemost 1995; 74:1474-1477. (Pubitemid 26018664)
    • (1995) Thrombosis and Haemostasis , vol.74 , Issue.6 , pp. 1474-1477
    • Lormeau, J.C.1    Herault, J.P.2
  • 9
    • 0022394350 scopus 로고
    • 1H-NMR spectra of synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: Evidence for conformational peculiarity of the sulfated iduronate residue
    • DOI 10.1016/0006-291X(85)91655-9
    • Torri G, Casu B, Gatti G, Petitou M, Choay J, Jacquinet JC, Sinay P. Monoand bidimensional 500 MHz 1H-NMR spectra of a synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: evidence for conformational peculiarity of the sulfated iduronate residue. Biochem Biophys Res Commun 1985; 128:134-140. (Pubitemid 16235142)
    • (1985) Biochemical and Biophysical Research Communications , vol.128 , Issue.1 , pp. 134-140
    • Torri, G.1    Casu, B.2    Gatti, G.3
  • 10
    • 0030952743 scopus 로고    scopus 로고
    • Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide
    • DOI 10.1016/S0049-3848(97)00042-X, PII S004938489700042X
    • Walenga JM, Jeske WP, Bara L, Samama MM, Fareed J. Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide. Thromb Res 1997; 86:1-36. (Pubitemid 27272341)
    • (1997) Thrombosis Research , vol.86 , Issue.1 , pp. 1-36
    • Walenga, J.M.1    Jeske, W.P.2    Bara, L.3    Samama, M.M.4    Fareed, J.5
  • 11
    • 0023923422 scopus 로고
    • The inhibition of the generation of thrombin and the antithrombotic effect of a pentasaccharide with sole antifactor Xa activity
    • Walenga JM, Bara L, Petitou M, Samama M, Fareed J, Choay J, et al. The inhibition of the generation of thrombin and the antithrombotic effect of a pentasaccharide with sole antifactor Xa activity. Thromb Res 1988; 51:23-33.
    • (1988) Thromb. Res. , vol.51 , pp. 23-33
    • Walenga, J.M.1    Bara, L.2    Petitou, M.3    Samama, M.4    Fareed, J.5    Choay, J.6
  • 12
    • 34347393477 scopus 로고    scopus 로고
    • Hereditary and acquired antithrombin deficiency: Epidemiology, pathogenesis and treatment options
    • DOI 10.2165/00003495-200767100-00005
    • Maclean PS, Tait RC. Hereditary and acquired antithrombin deficiency: epidemiology, pathogenesis, and treatment options. Drugs 2007; 67:1429-1440. (Pubitemid 47026392)
    • (2007) Drugs , vol.67 , Issue.10 , pp. 1429-1440
    • Maclean, P.S.1    Tait, R.C.2
  • 13
    • 0020919882 scopus 로고
    • Newer avenues in the monitoring of antithrombotic therapy
    • Walenga JM, Fareed J, Messmore HL. Newer avenues in the monitoring of antithrombotic therapy. Semin Thromb Hemost 1983; 9:346-354.
    • (1983) Semin Thromb Hemost , vol.9 , pp. 346-354
    • Walenga, J.M.1    Fareed, J.2    Messmore, H.L.3
  • 14
    • 0022256999 scopus 로고
    • A modified stasis thrombosis model to study the antithrombotic actions of heparin and its fractions
    • Fareed J, Walenga JM, Kumar A, Rock A. A modified stasis-thrombosis model to study the antithrombotic actions of heparin and its fractions. Semin Thromb Hemost 1985; 11:155-175. (Pubitemid 15057128)
    • (1985) Seminars in Thrombosis and Hemostasis , vol.11 , Issue.2 , pp. 155-175
    • Fareed, J.1    Walenga, J.M.2    Kumar, A.3    Rock, A.4
  • 15
    • 79955052500 scopus 로고
    • Antithrombotic activity of heparin and low molecular weight heparin in animals treated with anti-ATIII antibodies
    • Parma B, Bergonzini GL, Bianchini P, Osima B. Antithrombotic activity of heparin and low molecular weight heparin in animals treated with anti-ATIII antibodies. Thromb Haemorrhagic Disord 1991; 3:13-15.
    • (1991) Thromb. Haemorrhagic. Disord. , vol.3 , pp. 13-15
    • Parma, B.1    Bergonzini, G.L.2    Bianchini, P.3    Osima, B.4
  • 19
    • 0021017904 scopus 로고
    • Molar antithrombin concentration in normal human plasma
    • Conrad J, Brosstad F, Lie Larson M, Samama M, Abildgaard U. Molar antithrombin concentration in normal human plasma. Haemostasis 1983; 13:363-368. (Pubitemid 14152590)
    • (1983) Haemostasis , vol.13 , Issue.6 , pp. 363-368
    • Conard, J.1    Brosstad, F.2    Larsen, M.L.3
  • 20
    • 69849102090 scopus 로고    scopus 로고
    • Catheter-related thrombosis: Biological and clinical evidence for risk with currently available anticoagulants
    • Montalescot G, Walenga JM. Catheter-related thrombosis: biological and clinical evidence for risk with currently available anticoagulants. Clin Appl Thromb Hemost 2009; 15:183-196.
    • (2009) Clin. Appl. Thromb. Hemost. , vol.15 , pp. 183-196
    • Montalescot, G.1    Walenga, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.