Oral valganciclovir treatment for congenital cytomegalovirus infection

Pediatrics International

Volumn 53, Issue 2, 2011, Pages 249-252

  Imamura, Takashi ^a   Suzutani, Tatsuo ^a   Ogawa, Hiroshi ^a   Asano, Kimisato ^a   Nomoto, Mika ^a   Matsui, Takamichi ^a   Momoi, Nobuo ^a   Ikuta, Kazufumi ^a   Inoue, Naoki ^b   Hosoya, Mitsuaki ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

cytomegalovirus infection; oral valganciclovir; progressive hearing loss

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; VALGANCICLOVIR;

ARTICLE; AUDIOMETRY; CASE REPORT; CONGENITAL MALFORMATION; CYTOMEGALOVIRUS INFECTION; ECHOGRAPHY; EYE EXAMINATION; HEARING LOSS; HEART VENTRICLE HYPERTROPHY; HEPATITIS; HEPATOSPLENOMEGALY; HUMAN; HYPERBILIRUBINEMIA; INFANT; INTRAUTERINE GROWTH RETARDATION; MALE; NEUTROPENIA; NEWBORN SCREENING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; THROMBOCYTOPENIA; VIRUS LOAD;

ADMINISTRATION, ORAL; ADULT; ANTIVIRAL AGENTS; AUDIOMETRY; CYTOMEGALOVIRUS INFECTIONS; DISEASE PROGRESSION; FEMALE; GANCICLOVIR; HEARING LOSS; HUMANS; INFANT; INFANT, NEWBORN; NEONATAL SCREENING; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS;

EID: 79955057815     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2010.03217.x     Document Type: Article

References (17)

1. Boppana SB, Pass RF, Britt WS, Stagno S, Alford CA,. Symptomatic congenital cytomegalovirus infection: Neonatal morbidity and mortality. Pediatr. Infect. Dis. J. 1992; 11: 93-9.
2. Pass RF, Stagno S, Meyers GJ, Alford CA,. Outcome of symptomatic congenital cytomegalovirus infection: Results of long-term longitudinal follow-up. Pediatrics 1980; 66: 758-62. (Pubitemid 11250436)
3. Dahle AJ, McCollister FP, Stagno S, Reynolds DW, Hoffman HE,. Progressive hearing impairment in children with congenital cytomegalovirus infection. J. Speech. Hear. Disord. 1979; 44: 220-9. (Pubitemid 9188962)
4. Boppana SB, Fowler KB, Britt WJ, Stagno S, Pass RF,. Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus. Pediatrics 1999; 104: 55-60. (Pubitemid 29315847)
5. Whitley RJ, Cloud G, Gruber W, et al, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: Result of a phase II study. J. Infect. Dis. 1997; 175: 1080-6. (Pubitemid 27176494)
6. Marshall BC, Koch WC,. Antivirals for cytomegalovirus infection in neonates and infants: Focus on pharmacokinetics, formulations, dosing, and adverse events. Paediatr. Drugs 2009; 11: 309-21.
7. Fowler KB, Boppana SB,. Congenital cytomegalovirus (CMV) infection and hearing deficit. J. Clin. Virol. 2006; 35: 226-31. (Pubitemid 43053405)
8. Michaels MG, Greenberg DP, Sabo DL, Wald ER,. Treatment of children with congenital cytomegalovirus infection with ganciclovir. Pediatr. Infect. Dis. J. 2003; 22: 504-8. (Pubitemid 36782189)
9. Kimberlin DW, Lin CY, Sanchez PJ, et al, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: A randomized, controlled trial. J. Pediatr. 2003; 143: 16-25. (Pubitemid 36928564)
10. Smets K, De Coen K, Dhooge I, et al,. Selecting neonates with congenital cytomegalovirus infection for ganciclovir therapy. Eur. J. Pediatr. 2006; 165: 885-90. (Pubitemid 44627775)
11. Rivera LB, Boppana SB, Fowler KB, Britt WJ, Stagno S, Pass RF,. Predictors of hearing loss in children with symptomatic congenital cytomegalovirus infection. Pediatrics 2002; 110: 762-7.
12. Bradford RD, Cloud G, Lakeman AD, et al, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Detection of cytomegalovirus (CMV) DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the central nervous system. J. Infect. Dis. 2005; 191: 227-33. (Pubitemid 40096380)
13. Chiba H, Ito T, Watanabe T, et al,. Clinical Study of Threshold Change by objective audiometry in infants. Audiol. Jpn. 2007; 50: 174-9.
14. Acosta EP, Brundage RC, King JR, et al, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Ganciclovir population pharmacokinetics in neonates following intravenous administration of ganciclovir and oral administration of a liquid valganciclovir formulation. Clin. Pharmacol. Ther. 2007; 81: 867-72. (Pubitemid 46788295)
15. Galli L, Novelli A, Chiappini E, et al,. Valganciclovir for congenital CMV infection: A pilot study on plasma concentration in newborns and infants. Pediatr. Infect. Dis. J. 2007; 26: 451-3. (Pubitemid 46789332)
16. Lombardi G, Garofoli F, Villani P, et al,. Oral valganciclovir treatment in newborns with symptomatic congenital cytomegalovirus infection. Eur. J. Clin. Microbiol. Infect. Dis. 2009; 28: 1465-70.
17. Nassetta L, Kimberlin D, Whitley R,. Treatment of congenital cytomegalovirus infection: Implications for future therapeutic strategies. J. Antimicrob. Chemother. 2009; 63: 862-7.