Use of tissue cross-reactivity studies in the development of antibody-based biopharmaceuticals: history, experience, methodology, and future directions.

Toxicologic pathology

Volumn 38, Issue 7, 2010, Pages 1138-1166

  Leach, Michael W ^a   Halpern, Wendy G ^b   Johnson, Carol W ^b   Rojko, Jennifer L ^b   MacLachlan, Tim K ^b   Chan, Curtis M ^b   Galbreath, Elizabeth J ^b   Ndifor, Anthony M ^b   Blanset, Diann L ^b   Polack, Evelyne ^b   Cavagnaro, Joy A ^b  

^a PFIZER INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY;

ANIMAL; ANTIBODY COMBINING SITE; ARTICLE; CROSS REACTION; DRUG DESIGN; DRUG DEVELOPMENT; DRUG SCREENING; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METHODOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; CROSS REACTIONS; DRUG DESIGN; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HUMANS; IMMUNOHISTOCHEMISTRY;

EID: 79955045375     PISSN: None     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623310382559     Document Type: Article

References (0)