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Volumn 215, Issue 1, 2011, Pages 81-92

Interactive effects of mGlu5 and 5-HT2A receptors on locomotor activity in mice

Author keywords

5 HT2A receptors; Hallucinogen; Locomotor activity; Metabotropic glutamate receptors; Mice; Serotonin

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 2,5 DIMETHOXY 4 METHYLAMPHETAMINE; METABOTROPIC RECEPTOR 5; SEROTONIN 2A RECEPTOR; VOLINANSERIN;

EID: 79955037647     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-010-2115-1     Document Type: Article
Times cited : (30)

References (56)
  • 1
    • 0032527894 scopus 로고    scopus 로고
    • Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine
    • B Adams B Moghaddam 1998 Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine J Neurosci 18 5545 5554 9651235 1:CAS:528:DyaK1cXksFartLY%3D (Pubitemid 28311969)
    • (1998) Journal of Neuroscience , vol.18 , Issue.14 , pp. 5545-5554
    • Adams, B.1    Moghaddam, B.2
  • 2
    • 0031006582 scopus 로고    scopus 로고
    • Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells
    • DOI 10.1016/S0028-3908(97)00051-8, PII S0028390897000518
    • GK Aghajanian GJ Marek 1997 Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells Neuropharmacology 36 589 599 9225284 10.1016/S0028-3908(97)00051-8 1:CAS:528:DyaK2sXktlSmsLo%3D (Pubitemid 27272104)
    • (1997) Neuropharmacology , vol.36 , Issue.4-5 , pp. 589-599
    • Aghajanian, G.K.1    Marek, G.J.2
  • 4
    • 60149095737 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-dependent long-term potentiation
    • 19705571 10.1016/j.neuropharm.2009.01.002 1:CAS:528:DC%2BD1MXit1Oqt7c%3D
    • R Anwyl 2009 Metabotropic glutamate receptor-dependent long-term potentiation Neuropharmacology 56 735 740 19705571 10.1016/j.neuropharm.2009.01. 002 1:CAS:528:DC%2BD1MXit1Oqt7c%3D
    • (2009) Neuropharmacology , vol.56 , pp. 735-740
    • Anwyl, R.1
  • 5
    • 20044385283 scopus 로고    scopus 로고
    • Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice
    • DOI 10.1007/s00213-004-2108-z
    • MA Benneyworth RL Smith RJ Barrett E Sanders-Bush 2005 Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6 J mice Psychopharmacology (Berl) 179 854 862 10.1007/s00213-004-2108-z 1:CAS:528:DC%2BD2MXjvF2ks7s%3D (Pubitemid 40767905)
    • (2005) Psychopharmacology , vol.179 , Issue.4 , pp. 854-862
    • Benneyworth, M.A.1    Smith, R.L.2    Barrett, R.J.3    Sanders-Bush, E.4
  • 6
    • 34547198448 scopus 로고    scopus 로고
    • A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis
    • DOI 10.1124/mol.107.035170
    • MA Benneyworth Z Xiang RL Smith EE Garcia PJ Conn E Sanders-Bush 2007 A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis Mol Pharmacol 72 477 484 17526600 10.1124/mol.107.035170 1:CAS:528:DC%2BD2sXosVKrt7o%3D (Pubitemid 47124127)
    • (2007) Molecular Pharmacology , vol.72 , Issue.2 , pp. 477-484
    • Benneyworth, M.A.1    Xiang, Z.2    Smith, R.L.3    Garcia, E.E.4    Conn, P.J.5    Sanders-Bush, E.6
  • 7
    • 3242752882 scopus 로고    scopus 로고
    • Interactions of the mGluR5 gene with breeding and maternal factors on startle and prepulse inhibition in mice
    • 15184109 10.1007/BF03033300
    • SA Brody MA Geyer 2004 Interactions of the mGluR5 gene with breeding and maternal factors on startle and prepulse inhibition in mice Neurotox Res 6 79 90 15184109 10.1007/BF03033300
    • (2004) Neurotox Res , vol.6 , pp. 79-90
    • Brody, S.A.1    Geyer, M.A.2
  • 8
    • 0842264953 scopus 로고    scopus 로고
    • Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors
    • DOI 10.1038/sj.mp.4001404
    • SA Brody SC Dulawa F Conquet MA Geyer 2004 Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors Mol Psychiatry 9 35 41 14699440 10.1038/sj.mp.4001404 1:CAS:528:DC%2BD3sXhtVWhtr7P (Pubitemid 38175080)
    • (2004) Molecular Psychiatry , vol.9 , Issue.1 , pp. 35-41
    • Brody, S.A.1    Dulawa, S.C.2    Conquet, F.3    Geyer, M.A.4
  • 11
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • PJ Conn JP Pin 1997 Pharmacology and functions of metabotropic glutamate receptors Annu Rev Pharmacol Toxicol 37 205 237 9131252 10.1146/annurev. pharmtox.37.1.205 1:CAS:528:DyaK2sXisl2ktr0%3D (Pubitemid 27238875)
    • (1997) Annual Review of Pharmacology and Toxicology , vol.37 , pp. 205-237
    • Conn, P.J.1    Pin, J.-P.2
  • 12
    • 0033612553 scopus 로고    scopus 로고
    • Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat
    • DOI 10.1002/(SICI)1096-9861(19990628)409:2<187::AID-CNE2>3.0.CO;2-P
    • V Cornea-Hebert M Riad C Wu SK Singh L Descarries 1999 Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat J Comp Neurol 409 187 209 10379914 10.1002/(SICI)1096- 9861(19990628)409:2<187::AID-CNE2>3.0.CO;2-P 1:CAS:528:DyaK1MXjvFGmtbg%3D (Pubitemid 29264253)
    • (1999) Journal of Comparative Neurology , vol.409 , Issue.2 , pp. 187-209
    • Cornea-Hebert, V.1    Riad, M.2    Wu, C.3    Singh, S.K.4    Descarries, L.5
  • 13
    • 43449131567 scopus 로고    scopus 로고
    • Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm
    • DOI 10.1097/FBP.0b013e3282feb0ac, PII 0000887720080500000007
    • JM Darrah MR Stefani B Moghaddam 2008 Interaction of N-methyl-d-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm Behav Pharmacol 19 225 234 18469540 10.1097/FBP.0b013e3282feb0ac 1:CAS:528:DC%2BD1cXls1Kmsbw%3D (Pubitemid 351670403)
    • (2008) Behavioural Pharmacology , vol.19 , Issue.3 , pp. 225-234
    • Darrah, J.M.1    Stefani, M.R.2    Moghaddam, B.3
  • 15
    • 35748980554 scopus 로고    scopus 로고
    • 2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test
    • DOI 10.1007/s00213-007-0891-z
    • PJ Fletcher M Tampakeras J Sinyard GA Higgins 2007 Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test Psychopharmacology 195 223 234 17673981 10.1007/s00213-007-0891-z 1:CAS:528:DC%2BD2sXht1CltbrO (Pubitemid 350045843)
    • (2007) Psychopharmacology , vol.195 , Issue.2 , pp. 223-234
    • Fletcher, P.J.1    Tampakeras, M.2    Sinyard, J.3    Higgins, G.A.4
  • 16
    • 0033797463 scopus 로고    scopus 로고
    • Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors
    • 11027922 10.1016/S0893-133X(00)00136-6 1:CAS:528:DC%2BD3cXntF2iu7Y%3D
    • JC Gewirtz GJ Marek 2000 Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors Neuropsychopharmacology 23 569 576 11027922 10.1016/S0893-133X(00)00136-6 1:CAS:528:DC%2BD3cXntF2iu7Y%3D
    • (2000) Neuropsychopharmacology , vol.23 , pp. 569-576
    • Gewirtz, J.C.1    Marek, G.J.2
  • 17
    • 73449137227 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated long-term depression: Molecular mechanisms
    • 19926678 10.1124/pr.109.001735 1:CAS:528:DC%2BC3cXhs1Wrtr7F
    • CM Gladding SM Fitzjohn E Molnar 2009 Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms Pharmacol Rev 61 395 412 19926678 10.1124/pr.109.001735 1:CAS:528:DC%2BC3cXhs1Wrtr7F
    • (2009) Pharmacol Rev , vol.61 , pp. 395-412
    • Gladding, C.M.1    Fitzjohn, S.M.2    Molnar, E.3
  • 19
    • 61949104116 scopus 로고    scopus 로고
    • Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: Association with N-methyl-d-aspartic acid receptor up-regulation
    • 18593507 10.1017/S1461145708009085 1:CAS:528:DC%2BD1cXhsFWktbfM
    • L Gray M van den Buuse E Scarr B Dean AJ Hannan 2009 Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor up-regulation Int J Neuropsychopharmacol 12 45 60 18593507 10.1017/S1461145708009085 1:CAS:528:DC%2BD1cXhsFWktbfM
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 45-60
    • Gray, L.1    Van Den Buuse, M.2    Scarr, E.3    Dean, B.4    Hannan, A.J.5
  • 20
    • 22544449233 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia
    • DOI 10.1002/syn.20164
    • DS Gupta RE McCullumsmith M Beneyto V Haroutunian KL Davis JH Meador-Woodruff 2005 Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia Synapse 57 123 131 15945063 10.1002/syn.20164 1:CAS:528:DC%2BD2MXmslGgsLo%3D (Pubitemid 41023469)
    • (2005) Synapse , vol.57 , Issue.3 , pp. 123-131
    • Gupta, D.S.1    McCullumsmith, R.E.2    Beneyto, M.3    Haroutunian, V.4    Davis, K.L.5    Meador-Woodruff, J.H.6
  • 22
    • 0036945935 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity
    • DOI 10.1016/S0028-3908(02)00332-5
    • SA Henry V Lehmann-Masten F Gasparini MA Geyer A Markou 2002 The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity Neuropharmacology 43 1199 1209 12527469 10.1016/S0028-3908(02)00332-5 1:CAS:528:DC%2BD3sXislOguw%3D%3D (Pubitemid 36084431)
    • (2002) Neuropharmacology , vol.43 , Issue.8 , pp. 1199-1209
    • Henry, S.A.1    Lehmann-Masten, V.2    Gasparini, F.3    Geyer, M.A.4    Markou, A.5
  • 23
    • 2942650911 scopus 로고    scopus 로고
    • Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release
    • DOI 10.1038/sj.npp.1300417
    • H Homayoun MR Stefani BW Adams GD Tamagan B Moghaddam 2004 Functional interaction between NMDA and mGlu5 receptors: effects on working memory, instrumental learning, motor behaviors, and dopamine release Neuropsychopharmacology 29 1259 1269 15010696 10.1038/sj.npp.1300417 1:CAS:528:DC%2BD2cXkvFWltrc%3D (Pubitemid 38780649)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.7 , pp. 1259-1269
    • Homayoun, H.1    Stefani, M.R.2    Adams, B.W.3    Tamagan, G.D.4    Moghaddam, B.5
  • 24
    • 0035869454 scopus 로고    scopus 로고
    • Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey substantia Nigra
    • GW Hubert M Paquet Y Smith 2001 Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey Substantia nigra J Neurosci 21 1838 1847 11245668 1:CAS:528:DC%2BD3MXjslClsLY%3D (Pubitemid 32221367)
    • (2001) Journal of Neuroscience , vol.21 , Issue.6 , pp. 1838-1847
    • Hubert, G.W.1    Paquet, M.2    Smith, Y.3
  • 25
    • 0030431577 scopus 로고    scopus 로고
    • Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100, 907 as a potent 5-HT2A antagonist with a favorable CNS safety profile
    • 8627580 1:CAS:528:DyaK28XivFeht7s%3D
    • JH Kehne BM Baron AA Carr SF Chaney J Elands DJ Feldman, et al. 1996 Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100, 907 as a potent 5-HT2A antagonist with a favorable CNS safety profile J Pharmacol Exp Ther 277 968 981 8627580 1:CAS:528: DyaK28XivFeht7s%3D
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 968-981
    • Kehne, J.H.1    Baron, B.M.2    Carr, A.A.3    Chaney, S.F.4    Elands, J.5    Feldman, D.J.6
  • 26
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • DOI 10.1007/s00213-005-2200-z
    • JN Kew JA Kemp 2005 Ionotropic and metabotropic glutamate receptor structure and pharmacology Psychopharmacology (Berl) 179 4 29 10.1007/s00213-005-2200-z 1:CAS:528:DC%2BD2MXjtV2itbY%3D (Pubitemid 40576690)
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 4-29
    • Kew, J.N.C.1    Kemp, J.A.2
  • 28
    • 0035996485 scopus 로고    scopus 로고
    • Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice
    • DOI 10.1016/S0091-3057(02)00845-6, PII S0091305702008456
    • A Klodzinska M Bijak K Tokarski A Pilc 2002 Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice Pharmacol Biochem Behav 73 327 332 12117586 10.1016/S0091-3057(02)00845-6 1:CAS:528:DC%2BD38XltFaisLc%3D (Pubitemid 34765571)
    • (2002) Pharmacology Biochemistry and Behavior , vol.73 , Issue.2 , pp. 327-332
    • Klodzinska, A.1    Bijak, M.2    Tokarski, K.3    Pilc, A.4
  • 29
    • 0344835242 scopus 로고    scopus 로고
    • Modulation of phencyclidine-induced changes in locomotor activity and patterns in rats by serotonin
    • DOI 10.1016/S0014-2999(97)01557-4, PII S0014299997015574
    • K Krebs-Thomson V Lehmann-Masten S Naiem MP Paulus MA Geyer 1998 Modulation of phencyclidine-induced changes in locomotor activity and patterns in rats by serotonin Eur J Pharmacol 343 135 143 9570460 10.1016/S0014-2999(97) 01557-4 1:CAS:528:DyaK1cXhsFejt7c%3D (Pubitemid 28138595)
    • (1998) European Journal of Pharmacology , vol.343 , Issue.2-3 , pp. 135-143
    • Krebs-Thomson, K.1    Lehmann-Masten, V.2    Naiem, S.3    Paulus, M.P.4    Geyer, M.A.5
  • 30
    • 42749091423 scopus 로고    scopus 로고
    • The possible involvement of metabotropic glutamate receptors in schizophrenia
    • 18063347 10.1016/j.euroneuro.2007.11.001 1:CAS:528:DC%2BD1cXlsFOiurs%3D
    • A Krivoy T Fischel A Weizman 2008 The possible involvement of metabotropic glutamate receptors in schizophrenia Eur Neuropsychopharmacol 18 395 405 18063347 10.1016/j.euroneuro.2007.11.001 1:CAS:528:DC%2BD1cXlsFOiurs%3D
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 395-405
    • Krivoy, A.1    Fischel, T.2    Weizman, A.3
  • 31
    • 0030954048 scopus 로고    scopus 로고
    • Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP
    • YM Lu Z Jia C Janus JT Henderson R Gerlai JM Wojtowicz, et al. 1997 Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP J Neurosci 17 5196 5205 9185557 1:CAS:528:DyaK2sXktVOmsrc%3D (Pubitemid 27263833)
    • (1997) Journal of Neuroscience , vol.17 , Issue.13 , pp. 5196-5205
    • Lu, Y.-M.1    Jia, Z.2    Janus, C.3    Henderson, J.T.4    Gerlai, R.5    Wojtowicz, J.M.6    Roder, J.C.7
  • 32
    • 48949107355 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer v pyramidal cells of the rat prefrontal cortex
    • 18621097 10.1016/j.neulet.2008.06.083 1:CAS:528:DC%2BD1cXps1Gguro%3D
    • GJ Marek C Zhang 2008 Activation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer V pyramidal cells of the rat prefrontal cortex Neurosci Lett 442 239 243 18621097 10.1016/j.neulet.2008.06.083 1:CAS:528:DC%2BD1cXps1Gguro%3D
    • (2008) Neurosci Lett , vol.442 , pp. 239-243
    • Marek, G.J.1    Zhang, C.2
  • 34
    • 77149138329 scopus 로고    scopus 로고
    • Glutamatergic (N-methyl-d-aspartate receptor) hypofrontality in schizophrenia: Too little juice or a miswired brain?
    • 19933774 10.1124/mol.109.059865 1:CAS:528:DC%2BC3cXjt1ent74%3D
    • GJ Marek B Behl AY Bespalov G Gross Y Lee H Schoemaker 2010 Glutamatergic (N-methyl-d-aspartate receptor) hypofrontality in schizophrenia: too little juice or a miswired brain? Mol Pharmacol 77 317 326 19933774 10.1124/mol.109.059865 1:CAS:528:DC%2BC3cXjt1ent74%3D
    • (2010) Mol Pharmacol , vol.77 , pp. 317-326
    • Marek, G.J.1    Behl, B.2    Bespalov, A.Y.3    Gross, G.4    Lee, Y.5    Schoemaker, H.6
  • 35
    • 3142737454 scopus 로고    scopus 로고
    • Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice
    • AJ McGeehan PH Janak MF Olive 2004 Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, d-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice Psychopharmacology (Berl) 174 266 273 10.1007/s00213-003-1733-2 1:CAS:528:DC%2BD2cXltVSntbs%3D (Pubitemid 38916301)
    • (2004) Psychopharmacology , vol.174 , Issue.2 , pp. 266-273
    • Mcgeehan, A.J.1    Janak, P.H.2    Olive, M.F.3
  • 36
    • 0037439245 scopus 로고    scopus 로고
    • 2A receptors in the middle layers of the rat prelimbic prefrontal cortex
    • DOI 10.1016/S0306-4522(02)00580-8, PII S0306452202005808
    • LA Miner JR Backstrom E Sanders-Bush SR Sesack 2003 Ultrastructural localization of serotonin2A receptors in the middle layers of the rat prelimbic prefrontal cortex Neuroscience 116 107 117 12535944 10.1016/S0306-4522(02)00580- 8 1:CAS:528:DC%2BD3sXlt1ynsQ%3D%3D (Pubitemid 36110438)
    • (2003) Neuroscience , vol.116 , Issue.1 , pp. 107-117
    • Miner, L.A.H.1    Backstrom, J.R.2    Sanders-Bush, E.3    Sesack, S.R.4
  • 37
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • B Moghaddam B Adams A Verma D Daly 1997 Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex J Neurosci 17 2921 2927 9092613 1:CAS:528:DyaK2sXisValurk%3D (Pubitemid 27155025)
    • (1997) Journal of Neuroscience , vol.17 , Issue.8 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verma, A.3    Daly, D.4
  • 38
    • 67650796127 scopus 로고    scopus 로고
    • Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice
    • 19439499 10.1124/mol.109.056580 1:CAS:528:DC%2BD1MXptlegsr0%3D
    • G Molinaro A Traficante B Riozzi L Di Menna M Curto S Pallottino, et al. 2009 Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice Mol Pharmacol 76 379 387 19439499 10.1124/mol.109.056580 1:CAS:528: DC%2BD1MXptlegsr0%3D
    • (2009) Mol Pharmacol , vol.76 , pp. 379-387
    • Molinaro, G.1    Traficante, A.2    Riozzi, B.3    Di Menna, L.4    Curto, M.5    Pallottino, S.6
  • 39
    • 70349260680 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine
    • 19515968 10.1124/jpet.109.154138 1:CAS:528:DC%2BD1MXhtVyitLzK
    • MC Montana LF Cavallone KK Stubbert AD Stefanescu ED Kharasch RW Gereau 2009 The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine J Pharmacol Exp Ther 330 834 843 19515968 10.1124/jpet.109.154138 1:CAS:528:DC%2BD1MXhtVyitLzK
    • (2009) J Pharmacol Exp Ther , vol.330 , pp. 834-843
    • Montana, M.C.1    Cavallone, L.F.2    Stubbert, K.K.3    Stefanescu, A.D.4    Kharasch, E.D.5    Gereau, R.W.6
  • 40
    • 0027217320 scopus 로고
    • 2 receptors in the rat brain
    • DOI 10.1016/0306-4522(93)90241-7
    • DA Morilak SJ Garlow RD Ciaranello 1993 Immunocytochemical localization and description of neurons expressing serotonin2 receptors in the rat brain Neuroscience 54 701 717 8332257 10.1016/0306-4522(93)90241-7 1:CAS:528:DyaK3sXkvVOjs7s%3D (Pubitemid 23171330)
    • (1993) Neuroscience , vol.54 , Issue.3 , pp. 701-717
    • Morilak, D.A.1    Garlow, S.J.2    Ciaranello, R.D.3
  • 41
    • 4444279368 scopus 로고    scopus 로고
    • Lysergic acid diethylamide and [-]-2,5-dimethoxy-4-methylamphetamine increase extracellular glutamate in rat prefrontal cortex
    • DOI 10.1016/j.brainres.2004.07.044, PII S0006899304011813
    • JW Muschamp MJ Regina EM Hull JC Winter RA Rabin 2004 Lysergic acid diethylamide and [-]-2, 5-dimethoxy-4-methylamphetamine increase extracellular glutamate in rat prefrontal cortex Brain Res 1023 134 140 15364028 10.1016/j.brainres.2004.07.044 1:CAS:528:DC%2BD2cXnsFSrtbs%3D (Pubitemid 39195343)
    • (2004) Brain Research , vol.1023 , Issue.1 , pp. 134-140
    • Muschamp, J.W.1    Regina, M.J.2    Hull, E.M.3    Winter, J.C.4    Rabin, R.A.5
  • 42
    • 77953612697 scopus 로고    scopus 로고
    • Cognitive effects of group i metabotropic glutamate receptor ligands in the context of drug addiction
    • 20371237 10.1016/j.ejphar.2010.01.029 1:CAS:528:DC%2BC3cXntVShu7k%3D
    • MF Olive 2010 Cognitive effects of group I metabotropic glutamate receptor ligands in the context of drug addiction Eur J Pharmacol 639 47 58 20371237 10.1016/j.ejphar.2010.01.029 1:CAS:528:DC%2BC3cXntVShu7k%3D
    • (2010) Eur J Pharmacol , vol.639 , pp. 47-58
    • Olive, M.F.1
  • 45
    • 0027530661 scopus 로고
    • Three independent factors characterize spontaneous rat motor activity
    • MP Paulus MA Geyer 1993 Three independent factors characterize spontaneous rat motor activity Behav Brain Res 53 11 20 8466655 10.1016/S0166-4328(05)80262-1 1:STN:280:DyaK3s3itFKqsw%3D%3D (Pubitemid 23074026)
    • (1993) Behavioural Brain Research , vol.53 , Issue.1-2 , pp. 11-20
    • Paulus, M.P.1    Geyer, M.A.2
  • 46
    • 33846685161 scopus 로고    scopus 로고
    • The role of group I metabotropic glutamate receptors in schizophrenia
    • DOI 10.1007/s00726-006-0319-9, Special Issue: Focus on Metabotropic Glutamate Receptors
    • M Pietraszek J Nagel A Gravius D Schäfer W Danysz 2007 The role of group I metabotropic glutamate receptors in schizophrenia Amino Acids 32 173 178 16699816 10.1007/s00726-006-0319-9 1:CAS:528:DC%2BD2sXhtFyhtLo%3D (Pubitemid 46198740)
    • (2007) Amino Acids , vol.32 , Issue.2 , pp. 173-178
    • Pietraszek, M.1    Nagel, J.2    Gravius, A.3    Schafer, D.4    Danysz, W.5
  • 48
    • 0029002053 scopus 로고
    • Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain
    • 7636025 10.1002/cne.903550310 1:CAS:528:DyaK2MXlvFGmsLg%3D
    • C Romano MA Sesma CT McDonald K O'Malley AN Van den Pol JW Olney 1995 Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain J Comp Neurol 355 455 469 7636025 10.1002/cne.903550310 1:CAS:528:DyaK2MXlvFGmsLg%3D
    • (1995) J Comp Neurol , vol.355 , pp. 455-469
    • Romano, C.1    Sesma, M.A.2    McDonald, C.T.3    O'Malley, K.4    Van Den Pol, A.N.5    Olney, J.W.6
  • 49
    • 77953618742 scopus 로고    scopus 로고
    • Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator
    • 20371241 10.1016/j.ejphar.2010.02.057 1:CAS:528:DC%2BC3cXntVShu7g%3D
    • H Rosenbrock G Kramer S Hobson E Koros M Grundl M Grauert, et al. 2010 Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator Eur J Pharmacol 639 40 46 20371241 10.1016/j.ejphar.2010.02.057 1:CAS:528: DC%2BC3cXntVShu7g%3D
    • (2010) Eur J Pharmacol , vol.639 , pp. 40-46
    • Rosenbrock, H.1    Kramer, G.2    Hobson, S.3    Koros, E.4    Grundl, M.5    Grauert, M.6
  • 50
    • 0037630660 scopus 로고    scopus 로고
    • The hallucinogen 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI) increases cortical extracellular glutamate levels in rats
    • DOI 10.1016/S0304-3940(03)00547-0
    • JL Scruggs D Schmidt AY Deutch 2003 The hallucinogen 1-[2,5-dimethoxy-4- iodophenyl]-2-aminopropane (DOI) increases cortical extracellular glutamate levels in rats Neurosci Lett 346 137 140 12853103 10.1016/S0304-3940(03)00547-0 1:CAS:528:DC%2BD3sXltF2gtLY%3D (Pubitemid 36829280)
    • (2003) Neuroscience Letters , vol.346 , Issue.3 , pp. 137-140
    • Scruggs, J.L.1    Schmidt, D.2    Deutch, A.Y.3
  • 51
    • 0027378595 scopus 로고
    • Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain
    • DOI 10.1016/0304-3940(93)90227-C
    • R Shigemoto S Nomura H Ohishi H Sugihara S Nakanishi N Mizuno 1993 Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain Neurosci Lett 163 53 57 8295733 10.1016/0304-3940(93)90227-C 1:CAS:528:DyaK2cXisVWitg%3D%3D (Pubitemid 23349393)
    • (1993) Neuroscience Letters , vol.163 , Issue.1 , pp. 53-57
    • Shigemoto, R.1    Nomura, S.2    Ohishi, H.3    Sugihara, H.4    Nakanishi, S.5    Mizuno, N.6
  • 52
    • 41949132297 scopus 로고    scopus 로고
    • Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action
    • 18378264 10.1016/j.neuropharm.2008.02.006 1:CAS:528:DC%2BD1cXkvVOmsLg%3D
    • I Smolders R Clinckers A Meurs D De Bundel J Portelli G Ebinger, et al. 2008 Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action Neuropharmacology 54 1017 1028 18378264 10.1016/j.neuropharm.2008.02.006 1:CAS:528:DC%2BD1cXkvVOmsLg%3D
    • (2008) Neuropharmacology , vol.54 , pp. 1017-1028
    • Smolders, I.1    Clinckers, R.2    Meurs, A.3    De Bundel, D.4    Portelli, J.5    Ebinger, G.6
  • 53
    • 34948834664 scopus 로고    scopus 로고
    • Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent
    • DOI 10.1016/j.neuropharm.2007.08.002, PII S002839080700247X
    • K Stachowicz K Golembiowska M Sowa G Nowak E Chojnacka-Wojcik A Pilc 2007 Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent Neuropharmacology 53 741 748 17870136 10.1016/j.neuropharm.2007.08.002 1:CAS:528:DC%2BD2sXhtFGrsL3O (Pubitemid 47532144)
    • (2007) Neuropharmacology , vol.53 , Issue.6 , pp. 741-748
    • Stachowicz, K.1    Golembiowska, K.2    Sowa, M.3    Nowak, G.4    Chojnacka-Wojcik, E.5    Pilc, A.6
  • 54
    • 0028270378 scopus 로고
    • Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat
    • CM Testa DG Standaert AB Young JB Penney Jr 1994 Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat J Neurosci 14 3005 3018 8182455 1:CAS:528:DyaK2cXkt1Onu7c%3D (Pubitemid 24138989)
    • (1994) Journal of Neuroscience , vol.14 , Issue.5 , pp. 3005-3018
    • Testa, C.M.1    Standaert, D.G.2    Young, A.B.3    Penney Jr., J.B.4
  • 56
    • 77953285045 scopus 로고    scopus 로고
    • The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration
    • 20363246 10.1016/j.pbb.2010.03.014 1:CAS:528:DC%2BC3cXmslSisb0%3D
    • JW Young AK Goey A Minassian W Perry MP Paulus MA Geyer 2010 The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration Pharmacol Biochem Behav 96 7 15 20363246 10.1016/j.pbb.2010.03.014 1:CAS:528:DC%2BC3cXmslSisb0%3D
    • (2010) Pharmacol Biochem Behav , vol.96 , pp. 7-15
    • Young, J.W.1    Goey, A.K.2    Minassian, A.3    Perry, W.4    Paulus, M.P.5    Geyer, M.A.6


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