Science to practice: Can inflammatory arthritis be monitored by using MR imaging with injected hyperpolarized 13C-pyruvate?

Radiology

Volumn 259, Issue 2, 2011, Pages 309-310

  Larson, Peder E Z ^a   Gold, Garry E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 13; LACTIC ACID; PYRUVIC ACID; PYRUVIC ACID C 13; UNCLASSIFIED DRUG;

ARTHRITIS; ARTICLE; CLINICAL TRIAL (TOPIC); DIAGNOSTIC ACCURACY; DISEASE MODEL; DISEASE SEVERITY; HUMAN; HYPERPOLARIZATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT MONITORING; PRIORITY JOURNAL; PROSTATE CANCER; RHEUMATOID ARTHRITIS;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CARBON ISOTOPES; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; MAGNETIC RESONANCE SPECTROSCOPY; PYRUVATES; RATS;

EID: 79955031160     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.11110376     Document Type: Article

References (6)

1. MacKenzie JD , Yen YF , Mayer D , Tropp JS , Hurd RE , Spielman DM Detection of infl ammatory arthritis by using hyperpolarized 13 C-pyurvate with MR imaging and spectroscopy Radiology 2011 ; 259 ( 2 ): 414-420
2. Kurhanewicz J , Vigneron DB , Brindle K , et al Analysis of cancer metabolism by imaging hyperpolarized nuclei: Prospects for translation to clinical research Neoplasia 2011 ; 13 ( 2 ): 81-97
3. Biswal S , Resnick DL , Hoffman JM , Gambhir SS Molecular imaging: Integration of molecular imaging into the musculoskeletal imaging practice Radiology 2007 ; 244 ( 3 ): 651-671 (Pubitemid 47292078)
4. Ardenkjaer-Larsen JH , Fridlund B , Gram A , et al Increase in signal-to-noise ratio of 10,000 times in liquid-state NMR Proc Natl Acad Sci U S A 2003 ; 100 ( 18 ): 10158-10163 (Pubitemid 37071849)
5. Golman K , Ardenkjaer-Larsen JH , Petersson JS , Mansson S , Leunbach I Molecular imaging with endogenous substances Proc Natl Acad Sci U S A 2003 ; 100 ( 18 ): 10435-10439 (Pubitemid 37071896)
6. Wilson DM , Keshari KR , Larson PEZ , et al Multicompound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo J Magn Reson 2010 ; 205 ( 1 ): 141-147