A clinical evaluation of the efficacy and safety of singlet oxygen in cleansing and disinfecting stagnating wounds

Journal of Wound Care

Volumn 20, Issue 4, 2011, Pages 149-158

  Kammerlander, G ^a,b   Assadian, O ^c   Eberlein, T ^d   Zweitmuller, P ^b   Luchsinger, S ^e   Andriessen, A ^f  

^a CWM Academy   (Switzerland)

^b Wound Competence Centre   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

^d Andriessen Consultants ^*

^e Wound Competence Centre   (Switzerland)

^f Andriessen Consultants   (Switzerland)

Author keywords

Redox system; Singlet oxygen; Stagnating wounds; Wound cleansing; Wound disinfection

Indexed keywords

EID: 79955029492     PISSN: 09690700     EISSN: None     Source Type: Journal    
DOI: 10.12968/jowc.2011.20.4.149     Document Type: Article

References (26)

1. Bowler, P.G., Duerden, B.I., Armstrong, D.G. Wound microbiology and associated approaches to wound management. Clin Microbiol Rev 2001; 14:2, 244-269. (Pubitemid 32294670)
2. Dissemond. J., Schmid, E.N., Esser. S. et al. [Bacterial colonization of chronic wounds. Studies on outpatients in a university dermatology clinic with special consideration of ORSA]. [Article in German]. Hautarzt 2004; 55:3, 280-288. (Pubitemid 38404876)
3. Steed, D.L., Donohoe, D., Webster, M.W., Lindsley, L Effect of extensive debridement and treatment on the healing of diabetic foot ulcers. Diabetic Ulcer Study Group, J Am Coll Surg. 1996; 183: 1, 61-64. (Pubitemid 26234895)
4. Attinger, C.E. Janis. J.E., Steiberg J. Clinical approach to wounds: debridement and wound bed preparation including the use of dressings and wound-healing adjuvants. Plast Reconstr Surg. 2006; 117:(Suppl. 7), 72S-109S. (Pubitemid 44317773)
5. Kammerlander, G., Andriessen, A., Asmussen, P. et al. Role of the wet-to-dry phase of cleansing in preparing the chronic wound bed for dressing application. J Wound Care. 2005; 14:8, 349-352
6. James, G.A., Swogger, E., Wolcott, R.D. et al. Biofilms in chronic wounds. Wound Repair Regen. 2008; 16: 1, 37-44.
7. Dissemond. J., Goos, M., Esser, S. [Pathogenetic significance of methicillin resistant Staphylococcus aureus (MRSA) in chronic wounds]. [Article in German]. Vasa. 2003;32:3, 131-138. (Pubitemid 37127823)
8. Percival, S.L., Bowler, P.G., Russel, D. Bacterial resistance to silver in wound care. J Hospital Infect. 2005; 60: 1-7. (Pubitemid 40485843)
9. Andriessen. A., Eberlein. T.H. Assessment of a wound cleansing solution in the treatment of problem wounds. Wounds. 2008; 20:6, 171-175.
10. Kammerlander, G., Luchsinger, S., Locherer, E. et al. Mutizentrische Fallbeobachtungen sekudar heilender chronischer Wunden mit naszierendem Sauerstoff OI. Gesundheit/Medizin. 2009:40-44.
11. Marincic, D. Actimaris klinische ORL-Studie bei entzundlichen Haut- und Schleimhautprozessen. Hospitalis. 2010; 80:6/10, 144-151.
12. Rada, B., Leto. T.L. Oxidative innate immune defenses by Nox/Duox family NADPH oxidases. Contrib Microbiol. 2008; 15: 164-187.
13. Guzik T.J., Korbut, R., Adamek-Guzik, T. Nitric oxide and superoxide in inflammation and immune regulation. J Physiol Pharmacol. 2003; 54:4, 469-487. (Pubitemid 38029745)
14. Wondrak, G.T. Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid Redox Signal. 2009; 11: 12, 3013-3069.
15. Clark, R.A. Oxidative stress and "senescent" fibroblasts in non-healing wounds as potential therapeutic targets. J Invest Dermatol. 2008; 128: 10, 2361-2364.
16. Mendez, M.V. Stanley, A., Parker, H.Y. et al. Fibroblasts cultured from venous ulcers display cellular characteristics of senescence. J Vasc Surg. 1998; 28: 876-883. (Pubitemid 28521027)
17. Kammerlander, G. Lokaltherapeutische Standards für chronische Hautwunden. satisraction ana patient < [Book in German]. Taschenbuch, 2005.
18. Langley, R.G., Ellis, C.N. Evaluating psoriasis with Psoriasis Area and Severity Index, Psoriasis Global Assessment, and Lattice System Physician's Global Assessment. J Am Acad Dermatol 2004; 51:4, 563-569. (Pubitemid 39278075)
19. Athanasopoulos, A., Economopoulou, M., Orlova, V et al. The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms. Blood. 2006; 107:7, 2720-2727.
20. Grocott, P Evaluation of a tool used to assess the management of fungating wounds. J Wound Care. 1997; 6:9, 421-426.
21. Davies, B., Oberle, K. Dimensions of the supportive role of the nurse in palliative care. Oncol Nurs Forum. 1990; 17: 1, 87-94.
22. Hampson J. P The use of metronidazole in the treatment of malodorous wounds. J Wound Care. 1996; 5; 9:421-425.
23. Hoy A. Other symptom challenges.' In: Saunders, O. Sykes, N. (eds). The Management of Terminal Malignant Disease. Edward Arnold, 1993.
24. Krajnik, M., Zylicz, Z. Topical morphine for cutaneous cancer pain. Palliat Med. 1997; 11:4:325. (Pubitemid 27373038)
25. Mortimer, P Management of skin problems: Medical aspects. In: Doyle, D., Hanks, G.W.C., MacDonald, N. (eds). Oxford Textbook of Palliative Medicine. Oxford University Press, 1995.
26. Thomas, S., Hay, N.P. The anti-microbial properties of two metronidazole medicated dressings to treat malodorous wounds. The Pharmaceutical Journal. 1991:246:261-266.