Epigallocatechin-3-gallate potently inhibits the in vitro activity of hydroxy-3-methyl-glutaryl-CoA reductase

Journal of Lipid Research

Volumn 52, Issue 5, 2011, Pages 897-907

  Cuccioloni, Massimiliano ^a   Mozzicafreddo, Matteo ^a   Spina, Michele ^a   Tran, Chi Nhan ^a   Falconi, Maurizio ^a   Eleuteri, Anna Maria ^a   Angeletti, Mauro ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Cholesterol; Epigallocatechin 3 gallate; Inhibition; Reduced nicotinamide adenine dinucleotide phosphate

Indexed keywords

EPIGALLOCATECHIN GALLATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE (NADPH); PRAVASTATIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; ENZYME STRUCTURE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIVER MICROSOME; MOLECULAR DOCKING; OPTICAL BIOSENSOR; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SITE DIRECTED MUTAGENESIS; SPECTROPHOTOMETRY; TEA;

BIOSENSING TECHNIQUES; CATECHIN; COMPUTATIONAL BIOLOGY; ENZYME ACTIVATION; ENZYME ASSAYS; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MICROSOMES, LIVER; RECOMBINANT PROTEINS;

EID: 79955018181     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M011817     Document Type: Article

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