The effect of polyoxyethylene polymers on the transport of ranitidine in Caco-2 cell monolayers

International Journal of Pharmaceutics

Volumn 409, Issue 1-2, 2011, Pages 164-168

  Ashiru Oredope, Diane A I ^a   Patel, Nilesh ^b   Forbes, Ben ^b   Patel, Rajesh ^c   Basit, Abdul W ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Caco 2; Excipients; H2 antagonists; P glycoprotein; Permeability; Ranitidine

Indexed keywords

ADENOSINE TRIPHOSPHATASE; GLYCOPROTEIN P; MACROGOL; MACROGOL 200; MACROGOL 300; MACROGOL 400; MANNITOL; RANITIDINE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; CELL TRANSPORT; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ABSORPTION; DRUG TRANSPORT; ELECTRIC RESISTANCE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN INTERACTION;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; EXCIPIENTS; HISTAMINE H2 ANTAGONISTS; HUMANS; P-GLYCOPROTEIN; POLYETHYLENE GLYCOLS; RANITIDINE;

EID: 79955012696     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.02.059     Document Type: Article

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