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Volumn 6, Issue 12, 2010, Pages 696-698

Polycystic kidney disease: Do mTOR inhibitors still have a future in ADPKD?

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DERIVATIVE; EVEROLIMUS; IMMUNOSUPPRESSIVE AGENT; MTOR PROTEIN, HUMAN; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

EID: 79955007824     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2010.153     Document Type: Article
Times cited : (11)

References (10)
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    • (ed. Schrier, R. W., Lippincott Williams & Wilkins, Philadelphia
    • Ecder, T. et al. in Diseases of the Kidney and Urinary Tract (ed. Schrier, R. W.) 502-539 (Lippincott Williams & Wilkins, Philadelphia, 2007).
    • (2007) Diseases of the Kidney and Urinary Tract , pp. 502-539
    • Ecder, T.1
  • 2
    • 34047276812 scopus 로고    scopus 로고
    • Autosomal dominant polycystic kidney disease
    • Torres, V. E., Harris, P C. & Pirson, Y. Autosomal dominant polycystic kidney disease. Lancet 369, 1287-1301 (2007).
    • (2007) Lancet , vol.369 , pp. 1287-1301
    • Torres, V.E.1    Harris, P.C.2    Pirson, Y.3
  • 3
    • 0031459844 scopus 로고    scopus 로고
    • Mechanisms of progression in autosomal dominant polycystic kidney disease
    • Grantham, J. J. Mechanisms of progression in autosomal dominant polycystic kidney disease. Kidney Int. Suppl. 63, S93-S97 (1997).
    • (1997) Kidney Int. Suppl , vol.63 , pp. S93-S97
    • Grantham, J.J.1
  • 4
    • 33645769011 scopus 로고    scopus 로고
    • The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease
    • Shillingford, J. M. et al. The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease. Proc. Natl Acad. Sci. USA 103, 5466-5471 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 5466-5471
    • Shillingford, J.M.1
  • 5
    • 34447514158 scopus 로고    scopus 로고
    • Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease
    • Wu, M. et al. Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease. Kidney Blood Press. Res. 30, 253-259 (2007).
    • (2007) Kidney Blood Press. Res , vol.30 , pp. 253-259
    • Wu, M.1
  • 6
    • 40449138290 scopus 로고    scopus 로고
    • Sirolimus reduces polycystic liver volume in ADPKD patients
    • Qian, Q. et al. Sirolimus reduces polycystic liver volume in ADPKD patients. J. Am. Soc. Nephrol. 19, 631-638 (2008).
    • (2008) J. Am. Soc. Nephrol , vol.19 , pp. 631-638
    • Qian, Q.1
  • 7
    • 77956035166 scopus 로고    scopus 로고
    • Everolimus in patients with autosomal dominant polycystic kidney disease
    • Walz, G. et al. Everolimus in patients with autosomal dominant polycystic kidney disease. N. Engl. J. Med. 363, 830-840 (2010).
    • (2010) N. Engl. J. Med , vol.363 , pp. 830-840
    • Walz, G.1
  • 8
    • 77956029702 scopus 로고    scopus 로고
    • Sirolimus and kidney growth in autosomal dominant polycystic kidney disease
    • Serra, A. L. et al. Sirolimus and kidney growth in autosomal dominant polycystic kidney disease. N. Engl. J. Med. 363, 820-829 (2010).
    • (2010) N. Engl. J. Med , vol.363 , pp. 820-829
    • Serra, A.L.1
  • 9
    • 77952986486 scopus 로고    scopus 로고
    • Sirolimus therapy to halt the progression of ADPKD
    • Perico, N. et al. Sirolimus therapy to halt the progression of ADPKD. J. Am. Soc. Nephrol. 21, 1031-1040 (2010).
    • (2010) J. Am. Soc. Nephrol , vol.21 , pp. 1031-1040
    • Perico, N.1
  • 10
    • 34548432676 scopus 로고    scopus 로고
    • Computed tomography evaluation of autosomal dominant polycystic kidney disease progression: A progress report
    • Antiga, L. et al. Computed tomography evaluation of autosomal dominant polycystic kidney disease progression: a progress report. Clin. J. Am. Soc. Nephrol. 1, 754-760 (2006)
    • (2006) Clin. J. Am. Soc. Nephrol , vol.1 , pp. 754-760
    • Antiga, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.