Comparison of the in vivo hemodynamic effects of the antiarrhythmic agents vernakalant and flecainide in a rat hindlimb perfusion model

Journal of Cardiovascular Pharmacology

Volumn 57, Issue 4, 2011, Pages 463-468

  Allison, Beth ^a   Yang, Yi ^a   Pourrier, Marc ^a   Gibson, John K ^a  

^a Cardiome Pharma Corp   (Canada)

Author keywords

Antiarrhythmics; flecainide; hemodynamics; hypotension; vasodilation; vernakalant

Indexed keywords

FLECAINIDE; HEPARIN; VERNAKALANT;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIASTOLIC ARTERIAL PRESSURE; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; EXTRACORPOREAL CIRCULATION; HEART HEMODYNAMICS; HEART RATE; HINDLIMB; IN VIVO STUDY; LIMB PERFUSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; QRS COMPLEX; RAT; RENAL ARTERY; SYSTOLIC ARTERIAL PRESSURE; THROMBUS; VASCULAR RESISTANCE; VASCULARIZATION; VASOMOTOR REFLEX;

ANIMALS; ANISOLES; ANTI-ARRHYTHMIA AGENTS; AORTA, ABDOMINAL; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLECAINIDE; HINDLIMB; MALE; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR RESISTANCE;

EID: 79954995812     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e318210276b     Document Type: Article

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