Use of an HRP2-based rapid diagnostic test to guide treatment of children admitted to hospital in a malaria-endemic area of north-east Tanzania

Tropical Medicine and International Health

Volumn 16, Issue 5, 2011, Pages 545-550

  Mtove, George ^a   Nadjm, Behzad ^b   Amos, Ben ^c   Hendriksen, Ilse C E ^d   Muro, Florida ^e   Reyburn, Hugh ^b  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (Tanzania)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c Teule Hospital   (Tanzania)

^d MAHIDOL OXFORD TROPICAL MEDICINE RESEARCH UNIT   (Thailand)

^e KILIMANJARO CHRISTIAN MEDICAL CENTRE   (Tanzania)

Author keywords

Hospital; Malaria; Rapid diagnostic test; Severe

Indexed keywords

ANTIMALARIAL AGENT;

ANTIMALARIAL AGENT; BACTERIAL DISEASE; BLOOD; CHILD HEALTH; DISEASE PREVALENCE; DISEASE SEVERITY; ENDEMISM; INFECTIOUS DISEASE; MALARIA; MICROSCOPY;

AGE DISTRIBUTION; ARTICLE; BLOOD CELL COUNT; BLOOD CULTURE; CHILDHOOD DISEASE; CLINICAL EXAMINATION; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDEMIC DISEASE; FALSE POSITIVE RESULT; FEVER; HIGH RISK POPULATION; HOSPITAL ADMISSION; HUMAN; IMMUNOASSAY; MAJOR CLINICAL STUDY; MALARIA; MEDICAL HISTORY; PARASITEMIA; RAPID IMMUNOCHROMATOGRAPHIC TEST; SALMONELLOSIS; SENSITIVITY AND SPECIFICITY; TANZANIA;

ADOLESCENT; AGE DISTRIBUTION; ANIMALS; ANTIGENS, PROTOZOAN; CHILD; CHILD, PRESCHOOL; ENDEMIC DISEASES; EPIDEMIOLOGIC METHODS; FALSE POSITIVE REACTIONS; FEMALE; FEVER; HOSPITALIZATION; HOSPITALS, DISTRICT; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; REAGENT KITS, DIAGNOSTIC; RURAL HEALTH; TANZANIA;

TANZANIA;

SALMONELLA;

EID: 79954867568     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/j.1365-3156.2011.02737.x     Document Type: Article

References (20)

1. Bell DR, Wilson DW & Martin LB (2005) False-positive results of a Plasmodium falciparum histidine-rich protein 2-detecting malaria rapid diagnostic test due to high sensitivity in a community with fluctuating low parasite density. American Journal of Tropical Medicine and Hygiene 73, 199-203.
2. Birku Y, Welday D, Ayele D & Shepherd A (1999) Rapid diagnosis of severe malaria based on the detection of Pf-Hrp-2 antigen. Ethiopian Medical Journal 37, 173-179.
3. Biswas S, Tomar D & Rao DN (2005) Investigation of the kinetics of histidine-rich protein 2 and of the antibody responses to this antigen, in a group of malaria patients from India. Annals of Tropical Medicine and Parasitology 99, 553-562.
4. Brent AJ, Oundo JO, Mwangi I, Ochola L, Lowe B & Berkley JA (2006) Salmonella bacteremia in Kenyan children. Pediatric Infectious Disease Journal 25, 230-236.
5. Fryauff DJ, Gomez-Saladin E, Purnomo et al. (1997) Comparative performance of the ParaSight F test for detection of Plasmodium falciparum in malaria-immune and nonimmune populations in Irian Jaya, Indonesia. Bulletin of the World Health Organization 75, 547-552.
6. Gamboa D, Ho MF, Bendezu J et al. (2010) A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: implications for malaria rapid diagnostic tests. PLoS ONE 5, e8091.
7. Harris I, Sharrock W, Bain L et al. (2010) A large proportion of asymptomatic Plasmodium infections with low and sub-microscopic parasite densities in the low transmission setting of Temotu Province, Solomon Islands: challenges for malaria diagnostics in an elimination setting. Malaria Journal 9, 254.
8. Hopkins H, Kambale W, Kamya MR et al. (2007) Comparison of HRP2- and pLDH-based rapid diagnostic tests for malaria with longitudinal follow-up in Kampala, Uganda. American Journal of Tropical Medicine and Hygiene 76, 1092-1097.
9. Hopkins H, Bebell L, Kambale W, Dokomajilar C, Rosenthal PJ & Dorsey G (2008) Rapid diagnostic tests for malaria at sites of varying transmission intensity in Uganda. Journal of Infectious Diseases 197, 510-518.
10. Laurent A, Schellenberg J, Shirima K et al. (2010) Performance of HRP-2 based rapid diagnostic test for malaria and its variation with age in an area of intense malaria transmission in Tanzania. Malaria Journal 9, 294.
11. Nadjm B, Amos B, Mtove G et al. (2010) WHO guidelines for antimicrobial treatment in children admitted to hospital in an area of intense Plasmodium falciparum transmission: prospective study. BMJ 340, c1350.
12. Reyburn H, Mbatia R, Drakeley C et al. (2004) Overdiagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study. BMJ 329, 1212.
13. Reyburn H, Mbakiwa H, Mwangi R et al. (2007) Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomised trial. BMJ 334, 403.
14. Swarthout T, Counihan DH, Senga RK & Van den Broek I (2007) Paracheck-Pf accuracy and recently treated Plasmodium falciparum infections: is there a risk of over-diagnosis? Malaria Journal 6, 58.
15. WHO (2000a) Management of the Child with a Serious Infection or Severe Malnutrition. WHO, Geneva.
16. WHO (2000b) New perspectives in malaria diagnosis. WHO/CDS/RBM/2000.14.
17. WHO (2008) Malaria Rapid Diagnostic Test Performance: results of WHO Product Testing of Malaria RDTs, Round 1. TDR/WHO. WHO, Geneva.
18. WHO (2010) Guidelines for malaria diagnosis and treatment. WHO-Roll Back Malaria.
19. Wongsrichanalai C, Chuanak N, Tulyayon S et al. (1999) Comparison of a rapid field immunochromatographic test to expert microscopy for the detection of Plasmodium falciparum asexual parasitemia in Thailand. Acta Tropica 73, 263-273.
20. Zurovac D, Midia B, Ochola SA, English M & Snow RW (2006) Microscopy and outpatient malaria case management among older children and adults in Kenya. Tropical Medicine and International Health 11, 432-440.