Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats

Biochimica et Biophysica Acta - Biomembranes

Volumn 1808, Issue 6, 2011, Pages 1441-1447

  Sato, Masanobu ^a   Wakayama, Tomohiko ^a   Mamada, Hideaki ^a   Shirasaka, Yoshiyuki ^a   Nakanishi, Takeo ^a   Tamai, Ikumi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Excretion; Kidney; Reabsorption; Secretion; Urate

Indexed keywords

CARRIER PROTEIN; UNCLASSIFIED DRUG; URIC ACID; URIC ACID TRANSPORTER 1;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; MALE; MEMBRANE VESICLE; MOLECULAR CLONING; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; TISSUE DISTRIBUTION; XENOPUS LAEVIS;

ANIMALS; ANION TRANSPORT PROTEINS; BENZBROMARONE; BIOLOGICAL TRANSPORT; EPITHELIAL CELLS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; KINETICS; LACTATES; MALE; MICROVILLI; OOCYTES; PYRAZINAMIDE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; URIC ACID; XENOPUS LAEVIS;

RATTUS;

EID: 79954769480     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.11.002     Document Type: Article

References (37)

1. D.A. Sica, and A.C. Schoolwerth Renal handling of organic anions and cations: excretion of uric acid 7th ed. 2004 WB Saunders Philadelphia
2. N. Anzai, Y. Kanai, and H. Endou New insights into renal transport of urate Curr. Opin. Rheumatol. 19 2007 151 157 (Pubitemid 46208773)
3. H.K. Choi, D.B. Mount, and A.M. Reginato Pathogenesis of gout Ann. Intern. Med. 143 2005 499 516 (Pubitemid 41379398)
4. F. Jossa, E. Farinaro, S. Panico, V. Krogh, E. Celentano, R. Galasso, M. Mancini, and M. Trevisan Serum uric acid and hypertension: the Olivetti heart study J. Hum. Hypertens. 8 1994 677 681 (Pubitemid 24276965)
5. D.S. Freedman, D.F. Williamson, E.W. Gunter, and T. Byers Relation of serum uric acid to mortality and ischemic heart disease. The NHANES I Epidemiologic Follow-up Study Am. J. Epidemiol. 141 1995 637 644
6. M.J. Bos, P.J. Koudstaal, A. Hofman, J.C. Witteman, and M.M. Breteler Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study Stroke 37 2006 1503 1507 (Pubitemid 44305733)
7. D.H. Kang, T. Nakagawa, L. Feng, S. Watanabe, L. Han, M. Mazzali, L. Truong, R. Harris, and R.J. Johnson A role for uric acid in the progression of renal disease J. Am. Soc. Nephrol. 13 2002 2888 2897 (Pubitemid 35386908)
8. M. Rentzos, C. Nikolaou, M. Anagnostouli, A. Rombos, K. Tsakanikas, M. Economou, A. Dimitrakopoulos, M. Karouli, and D. Vassilopoulos Serum uric acid and multiple sclerosis Clin. Neurol. Neurosurg. 108 2006 527 531 (Pubitemid 44209214)
9. G. Toncev Therapeutic value of serum uric acid levels increasing in the treatment of multiple sclerosis Vojnosanit. Pregl. 63 2006 879 882
10. C.M. Knapp, C.S. Constantinescu, J.H. Tan, R. McLean, G.R. Cherryman, and I. Gottlob Serum uric acid levels in optic neuritis Mult. Scler. 10 2004 278 280 (Pubitemid 38807454)
11. T.S. Kim, C.U. Pae, S.J. Yoon, W.Y. Jang, N.J. Lee, J.J. Kim, S.J. Lee, C. Lee, I.H. Paik, and C.U. Lee Decreased plasma antioxidants in patients with Alzheimer's disease Int. J. Geriatr. Psychiatry 21 2006 344 348
12. L.M. de Lau, P.J. Koudstaal, A. Hofman, and M.M. Breteler Serum uric acid levels and the risk of Parkinson disease Ann. Neurol. 58 2005 797 800 (Pubitemid 41552559)
13. M.K. Kutzing, and B.L. Firestein Altered uric acid levels and disease states J. Pharmacol. Exp. Ther. 324 2008 1 7 (Pubitemid 350294141)
14. S.S. Daskalopoulou, V. Tzovaras, D.P. Mikhailidis, and M. Elisaf Effect on serum uric acid levels of drugs prescribed for indications other than treating hyperuricaemia Curr. Pharm. Des. 11 2005 4161 4175 (Pubitemid 41679180)
15. T. Iwanaga, M. Sato, T. Maeda, T. Ogihara, and I. Tamai Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter J. Pharmacol. Exp. Ther. 320 2007 211 217 (Pubitemid 46025736)
16. M. Sato, T. Iwanaga, H. Mamada, T. Ogihara, H. Yabuuchi, T. Maeda, and I. Tamai Involvement of uric acid transporters in alteration of serum uric acid level by angiotensin II receptor blockers Pharm. Res. 25 2008 639 646 (Pubitemid 351357726)
17. Y. Li, M. Sato, Y. Yanagisawa, H. Mamada, A. Fukushi, K. Mikami, Y. Shirasaka, and I. Tamai Effects of angiotensin II receptor blockers on renal handling of uric acid in rats Drug Metab. Pharmacokinet. 23 2008 263 270
18. T. Hamada, K. Ichida, M. Hosoyamada, E. Mizuta, K. Yanagihara, K. Sonoyama, S. Sugihara, O. Igawa, T. Hosoya, A. Ohtahara, C. Shigamasa, Y. Yamamoto, H. Ninomiya, and I. Hisatome Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients Am. J. Hypertens. 21 2008 1157 1162
19. I.M. Weiner Urate transport in the nephron Am. J. Physiol. 237 1979 F85 F92
20. A.M. Kahn, and E.J. Weinman Urate transport in the proximal tubule: in vivo and vesicle studies Am. J. Physiol. 249 1985 F789 F798
21. A. Enomoto, H. Kimura, A. Chairoungdua, Y. Shigeta, P. Jutabha, S.H. Cha, M. Hosoyamada, M. Takeda, T. Sekine, T. Igarashi, H. Matsuo, Y. Kikuchi, T. Oda, K. Ichida, T. Hosoya, K. Shimokata, T. Niwa, Y. Kanai, and H. Endou Molecular identification of a renal urate anion exchanger that regulates blood urate levels Nature 417 2002 447 452 (Pubitemid 34563537)
22. M. Hosoyamada, K. Ichida, A. Enomoto, T. Hosoya, and H. Endou Function and localization of urate transporter 1 in mouse kidney J. Am. Soc. Nephrol. 15 2004 261 268 (Pubitemid 38140766)
23. K. Ichida, M. Hosoyamada, I. Hisatome, A. Enomoto, M. Hikita, H. Endou, and T. Hosoya Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion J. Am. Soc. Nephrol. 15 2004 164 173 (Pubitemid 38020708)
24. S.A. Eraly, V. Vallon, T. Rieg, J.A. Gangoiti, W.R. Wikoff, G. Siuzdak, B.A. Barshop, and S.K. Nigam Multiple organic anion transporters contribute to net renal excretion of uric acid Physiol. Genomics 33 2008 180 192 (Pubitemid 351629526)
25. E. Hu, Z. Chen, T.A. Fredrickson, N. Spurr, S. Gentle, M. Sims, Y. Zhu, W. Halsey, S. Van Horn, J. Mao, G.M. Sathe, and D.P. Brooks Rapid isolation of tissue-specific genes from rat kidney Exp. Nephrol. 9 2001 156 164 (Pubitemid 32041494)
26. T. Iwanaga, D. Kobayashi, M. Hirayama, T. Maeda, and I. Tamai Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone Drug Metab. Dispos. 33 2005 1791 1795 (Pubitemid 41697263)
27. I. Tamai, A. Tsuji, and Y. Kin Carrier-mediated transport of cefixime, a new cephalosporin antibiotic, via an organic anion transport system in the rat renal brush-border membrane J. Pharmacol. Exp. Ther. 246 1988 338 344
28. Q. Li, Y. Sai, Y. Kato, H. Muraoka, I. Tamai, and A. Tsuji Transporter-mediated renal handling of nafamostat mesilate J. Pharm. Sci. 93 2004 262 272 (Pubitemid 38174249)
29. I. Tamai, T. Nakanishi, D. Kobayashi, K. China, Y. Kosugi, J. Nezu, Y. Sai, and A. Tsuji Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations Mol. Pharm. 1 2004 57 66
30. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
31. T. Wakayama, H. Nakata, M. Kurobo, Y. Sai, and S. Iseki Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis J. Histochem. Cytochem. 57 2009 351 362
32. E.J. Weinman, D. Steplock, W.N. Suki, and G. Eknoyan Urate reabsorption in proximal convoluted tubule of the rat kidney Am. J. Physiol. 231 1976 509 515
33. C.A. Polkowski, and S.M. Grassl Uric acid transport in rat renal basolateral membrane vesicles Biochim. Biophys. Acta 1146 1993 145 152 (Pubitemid 23067053)
34. T. Imaoka, H. Kusuhara, S. Adachi-Akahane, M. Hasegawa, N. Morita, H. Endou, and Y. Sugiyama The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules J. Am. Soc. Nephrol. 15 2004 2012 2022 (Pubitemid 39031340)
35. E. Gopal, Y.J. Fei, M. Sugawara, S. Miyauchi, L. Zhuang, P. Martin, S.B. Smith, P.D. Prasad, and V. Ganapathy Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate J. Biol. Chem. 279 2004 44522 44532 (Pubitemid 39430859)
36. E. Gopal, N.S. Umapathy, P.M. Martin, S. Ananth, J.P. Gnana-Prakasam, H. Becker, C.A. Wagner, V. Ganapathy, and P.D. Prasad Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney Biochim. Biophys. Acta 1768 2007 2690 2697 (Pubitemid 350060863)
37. L.J. Mandel Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport Annu. Rev. Physiol. 47 1985 85 101 (Pubitemid 15142373)