Novel design for drift tubes in ion mobility spectrometry for optimised resolution of peak clusters

International Journal for Ion Mobility Spectrometry

Volumn 14, Issue 1, 2011, Pages 31-38

  Hariharan, Chandrasekhara Bharadwaj ^a   Seifert, Luzia ^a   Baumbach, Jörg Ingo ^b   Vautz, Wolfgang ^a  

^a LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

2 Heptanone; 4 Heptanone; Acetone; Drift tube; Ion mobility spectrometry; Peak clusters; Resolution

Indexed keywords

DRIFT TUBE; HEPTANONE; ION MOBILITY SPECTROMETRY; PEAK CLUSTERS; RESOLUTION;

ACETONE; DRIFT CHAMBERS; ELECTRIC FIELDS; IONS; SPECTROMETRY;

TUBES (COMPONENTS);

EID: 79954743978     PISSN: 14356163     EISSN: 18654584     Source Type: Journal    
DOI: 10.1007/s12127-011-0059-8     Document Type: Article

References (27)

1. Langevin P (1905) Une formule fondamentale de théorie cinétique. Ann de Chim et de Phys 5: 245-288.
2. Cohen MJ, Karasek FW (1970) Plasma chromatography-a new dimension for gas chromatography and mass spectrometry. J Chromatogr Sci 8: 330-337.
3. Stach J, Baumbach JI (2002) Ion mobility spectrometry-Basic elements and applications. Int J Ion Mobil Spectrom 5(1): 1-21.
4. Louis RH, Hill HH (1990) Ion mobility spectrometry in analytical chemistry. Crit Rev Anal Chem 21(5): 321-355.
5. Eiceman GA, Karpas Z (2005) Ion Mobility Spectrometry. Taylor and Francis, 2005.
6. Westhoff M, Litterst P, Freitag L, Urfer W, Bader S, Baumbach JI (2009) Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: results of a pilot study. Thorax 64: 744-748.
7. Vautz W, Nolte J, Bufe A, Baumbach J, Peters M (2010) Analysis of mice's breath using gas chromatography ion mobility spectrometry. J Appl Physiol 108: 697-704.
8. Prasad S, Pierce K, Schmidt H, Rao J, Güth R, Bader S, Synovec R, Smith GB, Eiceman GA (2007) Analysis of bacteria by pyrolysis gas chromatography-differential mobility spectrometry and isolation of chemical components with a dependence on growth temperature. Analyst 132: 1031-1039.
9. Vautz W, Carstens ETH, Hirn A, Quintel M, Nolte J, Jünger M, Perl T (2010) Online determination of Plasma Propofol concentrations by expired air analysis. Int J Ion Mobil Spectrom 13(1): 37-40.
10. Westhoff M, Ruzsanyi V, Litterst P, Freitag L, Baumbach JI (2007) Ion mobility spectrometry-a new method for the fast detection of Sarkoidose in human breath?-Preliminary results of a feasibility study. J Physiol Pharmacol 58(5): 739-751.
11. Vautz W, Baumbach JI (2008) Exemplar application of multi-capillary column ion mobility spectrometry for biological and medical purpose. Int J Ion Mobil Spectrom 11: 35-41.
12. Baumbach JI (2006) Process analysis using ion mobility spectrometry. Anal Bioanal Chem 384: 1059-1070.
13. Bödeker B, Vautz W, Baumbach JI (2008) Peak comparison in MCC/IMS-Data-Searching for potential biomarkers in human breath data. Int J Ion Mobil Spectrom 11: 89-93.
14. Tang K, Shvartsburg AA, Lee H, Prior D, Buschbach M, Li F, Tolmachev A, Anderson G, Smith RD (2005) High-sensitivity ion mobility spectrometry/mass spectrometry using electrodynamic ion funnel interfaces. Anal Chem 77(10): 3330-3339.
15. Siems WF, Wu C, Tarver E, Hill HH (1994) Measuring the resolving power of ion mobility spectrometers. Anal Chem 66(23): 4195-4201.
16. Revercomb HE, Mason EA (1975) Theory of plasma chromatography/gaseous electrophoresis-a review. Anal Chem 47(7): 970-983.
17. Asbury GR, Hill HH (2000) Evaluation of ultrahigh resolution ion mobility spectrometry as an analytical separation device in chromatographic terms. J Microcolumn Sep 12(3): 172-178.
18. Ruzsanyi V, Baumbach JI, Sielemann S, Litterst P, Westhoff M, Freitag L (2005) Detection of human metabolites using multi-capillary columns coupled to ion mobility spectrometers. J Chromatogr A 1084: 145-151.
19. Baumbach JI, Eiceman GA (1999) Ion mobility spectrometry: arriving on-site and moving beyond a low profile. Appl Spectrosc 53(9): 338-355.
20. Davis D, Harden C, Shoff D, Bell S, Eiceman G, Ewing R (1994) Analysis of ion mobility spectra for mixed vapours using Gaussian deconvolution. Anal Chim Acta 289: 263-272.
21. Dugourd Ph, Hudgins RR, Clemmer DE, Jarrold MF (1997) High resolution ion mobility measurements. Rev Sci Instrum 68(2): 1122-1129.
22. Wu C, Siems W, Asbury R, Hill HH (1998) Electrospray ionisation high resolution ion mobility spectrometry-mass spectrometry. Anal Chem 70(23): 4929-4938.
23. Vautz W, Bödecker B, Bader S, Perl T (2009) An impeccable approach to obtain reproducible reduced ion mobilities. Int J Ion Mobil Spectrum 12(2): 47-57.
24. Deng C, Zhang J, Yu X, Zhang X (2004) Determination of acetone in human breath by gas chromatography-mass spectrometry and solid phase microextraction with on-fiber derivatization. J Chromatogr B 810(2): 269-275.
25. Statherropolous M, Sianos E, Agapiou A, Georgiadou A, Pappa A, Tzamtzis N, Giotaki H, Papageorgiou C, Kolostoumbis D (2005) Preliminary investigation of using volatile organic compounds from human expired air, blood and urine for locating entrapped people in earthquakes. J Chromatogr B 822: 112-117.
26. Smith S, Burden H, Persad R, Whittington K, de Lacy CB, Ratcliffe N, Probert C (2008) A comparative study of the analysis of human urine headspace using gas chromatography-mass spectrometry. J Breath Res 2(3): 184-193.
27. Erhart S, Amman A, Haberlandt E, Edlinger G, Schmid A, Filipiak W, Schwarz K, Mochalski P, Rostasy K, Karall D, Scholl S (2009) 3-Heptanone as a potential new marker for valporic acid therapy. J Breath Res 3(1): 376-381.