N-benzyl-3-sulfonamidopyrrolidines are a new class of bacterial DNA gyrase inhibitors

ACS Medicinal Chemistry Letters

Volumn 2, Issue 4, 2011, Pages 289-292

  Foss, Marie H ^a   Hurley, Katherine A ^b   Sorto, Nohemy A ^b   Lackner, Laura L ^b   Thornton, Kelsey M ^a   Shaw, Jared T ^b   Weibel, Douglas B ^a,c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of Wisconsin Madison   (United States)

Author keywords

534F6; antibiotics; DNA gyrase; gyramides; inhibitors

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL DNA; CIPROFLOXACIN; GYRAMIDE A; GYRAMIDE B; GYRAMIDE C; GYRASE INHIBITOR; PHENYLALANYLARGININE 2 NAPHTHYLAMIDE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DRUG DESIGN; DRUG IDENTIFICATION; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SALMONELLA ENTERICA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; NEGIBACTERIA; PSEUDOMONAS AERUGINOSA; SALMONELLA ENTERICA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

EID: 79954624232     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml1002822     Document Type: Article

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