Multivariate optimization of formulation variables influencing flurbiprofen proniosomes characteristics

Journal of Pharmaceutical Sciences

Volumn 100, Issue 6, 2011, Pages 2212-2221

  Zidan, Ahmed S ^a,b   Mokhtar, Mahmoud ^a  

^a Zagazig University   (Egypt)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Factorial design; Gels; Membrane transport; Percutaneous; Surfactants

Indexed keywords

CHOLESTEROL; FLURBIPROFEN; NONIONIC SURFACTANT;

ANIMAL TISSUE; ARTICLE; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; NONHUMAN; RABBIT; STEADY STATE;

EID: 79954622486     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22453     Document Type: Article

References (29)

1. Schreier H, Bouwstra J. 1994. Liposomes and niosomes as topical drug carriers: Dermal and transdermal drug delivery. J Control Release 30:1-15.
2. Aggarwal D, Kaur IP. 2005. Improved pharmacodynamics of timolol maleate from a mucoadhesive niosomal ophthalmic drug delivery system. Int J Pharm 290:155-159
3. Manconi M, Sinico C, Valenti D, Loy G, Fadda AM. 2002. Niosomes as carriers for tretinoin. I. Preparation and properties. Int J Pharm 234:237-248.
4. Hu C, Rhodes DG. 2000. Proniosomes: A novel drug carrier preparation. Int J Pharm 206(1-2):110-122.
5. Vora B, Khopade AJ, Jain NK. 1998. Proniosome based transdermal delivery of levonorgestrel for effective contraception. J Control Release 54:149-165.
6. Alsarra IA, Bosela AA, Ahmed SM, Mahrous GM. 2005. Proniosomes as a drug carrier for transdermal delivery of ketorolac. Eur J Pharm Biopharm 59(3):585-490.
7. Mohammed AR, Weston N, Coombes AGA, Fitzgerald M, Perrie Y. 2004. Liposome formulation of poorly water soluble drugs: Optimization of drug loading and ESEM analysis of stability. Int J Pharm 285:23-34.
8. Gregoriadis G. 1993. Liposome technology, 2nd ed. Boca Raton, Florida:CRC Press.
9. Gregoriadis G, Perrie Y. 2010. Liposomes. In Encyclopedia of Life Sciences (ELS); Chichester: John Wiley & Sons, Ltd.
10. Bernsdorff C, Wolff A, Winter R, Gratton E. 1997. Effect of hydrostatic pressure on water penetration and rotational dynamics in phospholipids-cholesterol bilayers. Biophys J 72:1264-1277.
11. Charoo NA, Shamsher AA, Kohli K, Pillai K, Rahman Z. 2008. Improvement in bioavailability of transdermally applied flurbiprofen using tulsi (Ocimum sanctum) and turpentine oil. Colloids Surf B Biointerfaces 65(2):300-307.
12. Sebastiani P, Nicoli S, Santi P. 2005. Effect of lactic acid and iontophoresis on drug permeation across rabbit ear skin. Int J Pharm 292:119-126.
13. Larrucea E, Arellano A, Santoyo S, Ygarrua P. 2001. Interaction of tenoxicam with cyclodextrins and its influence on the in vitro percutaneous penetration of the drug. Drug Dev Ind Pharm 27(3):25l-260.
14. Mura P, Faucci MT, Bramanti G, Corti P. 2000. Evaluation of transcutol as a clonazepam transdermal permeation enhancer from hydrophilic gel formulations. Eur J Pharm Sci 9:365-372.
15. Udupa N, Chandraprakash KS, Umadevi P, Pillai GK. 1993. Formulation and evaluation of methotrexate niosomes. Drug Dev Ind Pharm 19:1331-1342.
16. Hwang BY, Jung BH, Chung SJ, Lee MH, Shim CK. 1997. In vitro skin permeation of nicotine from proliposomes. J Contr Release 49:177-184.
17. Furlanetto S, Maestrelli F, Orlandini S, Mura P. 2003. Optimization of dissolution test precision for a ketoprofen oral extended-release product. J Pharm Biomed Anal 32:159-165.
18. Furlanetto S, Cirri M, Maestrelli F, Corti G, Mura P. 2006. Study of formulation variables influencing the drug release rate from matrix tablet by experimental design. Eur J Pharm Biopharm 62:77-84.
19. Gregoriadis G, Davis C. 1979. Stability of liposomes in vivo and in vitro is promoted by their cholesterol content in the presence of blood cells. Biochem Biophys Res Commun 90:1287-1293.
20. Yoshioka T, Sternberg B, Florence AT. 1994. Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 40, 60, and 80) and sorbitan triester (Span 85). Int J Pharm 105:1-6.
21. Hao Y, Zhao F, Li N, Yang Y, Li K. 2002. Studies on a high encapsulation of cholchicine by niosome system. Int J Pharm 244:73-80.
22. Mokhtar M, Sammour OA, Hammad MA, Megrab NA. 2008. Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes. Int J Pharm 361:104-111.
23. Kirby C, Clarke J, Gregoriadis G. 1980. Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro. Biochem J 186:591-598.
24. Uchegbu IF, Vyas SP. 1998. Non-ionic surfactant based vesicles (niosomes) in drug delivery. Int J Pharm 172:33-70.
25. Ladbrooke BD, Williams RM, Chapman D. 1968. Studies on lecithin-cholesterol-water interactions by differential scanning calorimetry and X-ray diffraction. Biochim Biophys Acta 150:333-340.
26. Papahadjopoulos D, Jacobson K, Nir S, Isac T. 1973. Phase transition in phospholipid vesicles: Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol. Biochim Biophys Acta 311:330-334.
27. David N, Rashmi SN. 1990. Elastic deformation and failure of lipid bilayer membranes containing cholesterol. Biophys J 58:997-1009.
28. Harrington, Jr. EC. 1965. The Desirability Function. Industrial Quality Control, 21(10): 494-498.
29. Gatza PE, McMillan RC. 1972. The use of experimental design and computerized data analysis in elastomer development studies, Division of Rubber Chemistry, American Chemical Society Fall Meeting, Cincinnati, Ohio, pp 3-6.