Heparinized cardiopulmonary bypass circuits and low systemic anticoagulation: An analysis of nearly 6000 patients undergoing coronary artery bypass grafting

Journal of Thoracic and Cardiovascular Surgery

Volumn 141, Issue 5, 2011, Pages 1145-1149

  Øvrum, Eivind ^a,b   Tangen, Geir ^a   Tølløfsrud, Stein ^a   Skeie, Bjørn ^a   Ringdal, Mari Anne L ^a   Istad, Reidar ^a   Øystese, Rolf ^a  

^a Oslo Heart Center   (Norway)

^b Box 2684 ^*  (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; HEPARIN;

ADULT; ANTICOAGULATION; ARTICLE; BLOOD BANK; BLOOD CLOTTING TIME; BLOOD TRANSFUSION; CARDIOPULMONARY BYPASS; CARDIOVASCULAR RISK; CONTROLLED STUDY; CONVALESCENCE; CORONARY ARTERY BYPASS GRAFT; DRUG DOSE REDUCTION; EXTRACORPOREAL CIRCULATION; EXTUBATION; FEMALE; HEART INFARCTION; HEPARINIZATION; HIGH RISK PATIENT; HOSPITAL DISCHARGE; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; MORTALITY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; ANTICOAGULANTS; BLOOD TRANSFUSION; CARDIOPULMONARY BYPASS; COATED MATERIALS, BIOCOMPATIBLE; CORONARY ARTERY BYPASS; EQUIPMENT DESIGN; FEMALE; HEPARIN; HUMANS; INTUBATION, INTRATRACHEAL; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NORWAY; OPERATIVE BLOOD SALVAGE; RESPIRATION, ARTIFICIAL; RISK ASSESSMENT; RISK FACTORS; STROKE; TIME FACTORS; TREATMENT OUTCOME;

EID: 79954616692     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2010.07.003     Document Type: Article

References (25)

1. H.K. Song, B.S. Diggs, M.S. Slater, S.W. Guyton, R.M. Ungerleider, and K.F. Welke Improved quality and cost-effectiveness of coronary artery bypass grafting in United States from 1988 to 2005 J Thorac Cardiovasc Surg 137 2009 65 69
2. V. Videm, J.L. Svennevig, E. Fosse, G. Semb, A. Østerud, and T.E. Mollnes Reduced complement activation with heparin-coated oxygenator and tubings in coronary bypass operations J Thorac Cardiovasc Surg 103 1992 806 813
3. Y.J. Gu, W. van Oeveren, C. Akkerman, P.W. Boonstra, R.J. Huyzen, and C.R. Wildevuur Heparin-coated circuits reduce the inflammatory response to cardiopulmonary bypass Ann Thorac Surg 55 1993 917 922 (Pubitemid 23130245)
4. E. Fosse, O. Moen, E. Johnson, G. Semb, V. Brockmeier, and T.E. Mollnes Reduced complement and granulocyte activation with heparin coated cardiopulmonary bypass Ann Thorac Surg 58 1994 472 477 (Pubitemid 24285121)
5. L.K. Von Segesser, B.M. Weiss, M. Pasic, E. Garcia, and M.I. Turina Risk and benefit of low systemic heparinization during open heart operations Ann Thorac Surg 58 1994 391 398 (Pubitemid 24285107)
6. G.S. Aldea, B.A. Doursounian, P. O'Gara, P. Treanor, O.M. Shapira, and H.L. Lazar Heparin-bonded circuits with a reduced anticoagulation protocol in primary CABG: a prospective, randomized study Ann Thorac Surg 62 1996 410 418 (Pubitemid 26259682)
7. E. Øvrum, E. m Holen, G. Tangen, F. Brosstad, M. Abdelnoor, and M.A.L. Ringdal Completely heparinized cardiopulmonary bypass and reduced systemic heparin: clinical and hemostatic effects Ann Thorac Surg 60 1995 365 371
8. E. Øvrum, G. Tangen, R. Øystese, M.A.L. Ringdal, and R. Istad Comparison of two heparin-coated extracorporeal circuits with reduced systemic anticoagulation in routine coronary artery bypass surgery J Thorac Cardiovasc Surg 121 2001 324 330 (Pubitemid 32150922)
9. E. Øvrum, G. Tangen, S. Tølløfsrud, and M.A.L. Ringdal Heparin-coated circuits and reduced systemic anticoagulation applied to 2500 consecutive first-time coronary artery bypass grafting procedures Ann Thorac Surg 76 2003 1144 1148 (Pubitemid 37204722)
10. E. Øvrum, E. m Holen, and G. Tangen Consistent non-pharmacologic blood conservation in primary and reoperative coronary artery bypass grafting Eur J Cardiothorac Surg 9 1995 30 35
11. M. Ranucci, A. Balduini, A. Ditta, A. Boncilli, and S. Brozzi A systematic review of biocompatible cardiopulmonary bypass circuits and clinical outcome Ann Thorac Surg 87 2009 1311 1319
12. L.H. Edmunds Jr. Surface-bond heparin - panacea or peril? Ann Thorac Surg 58 1994 285 286
13. E. Øvrum, F. Brosstad, E. m Holen, G. Tangen, and M. Abdelnoor Effects on coagulation and fibrinolysis with reduced versus full systemic heparinization and heparin-coated cardiopulmonary bypass Circulation 92 1995 2579 2584
14. G.S. Aldea, P. O'Gara, O.M. Shapira, T. Treanor, A. Osman, and E. Patalis Effect of anticoagulation protocol on outcome in patients undergoing CABG with heparin-bonded cardiopulmonary bypass circuits Ann Thorac Surg 65 1998 425 433 (Pubitemid 28083339)
15. M. Ranucci, A. Mazzucco, R. Pessotto, G. Grillone, V. Casati, and L. Porreca Heparin-coated circuits for high-risk patients: a multicenter, prospective, randomized trial Ann Thorac Surg 67 1999 994 1000 (Pubitemid 29238286)
16. E.J. Heyer, K.S. Lee, H.E. Manspeizer, L. Mongero, T.B. Spanier, and X. Caliste Heparin-bonded cardiopulmonary bypass circuits reduce cognitive dysfunction J Cardiothorac Vasc Anesth 16 2002 37 42 (Pubitemid 34163815)
17. N.G. Slater Autologous blood transfusion today Br J Clin Pract 46 1992 193 197
18. S. Westaby, R. Pillai, A. Parry, D. O'Regan, N. Giannopoulos, and K. Grebenik Does modern cardiac surgery require conventional intensive care? Eur J Cardiothorac Surg 7 1993 313 318
19. D.C.H. Cheng, J. Karski, C. Peniston, B. Asokumar, G. Raveendran, and J. Carroll Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial J Thorac Cardiovasc Surg 112 1996 755 764 (Pubitemid 26347032)
20. B. Kipfer, L. Engelberger, E. Gygax, U. Nydegger, and T. Carrel Is reduced systemic heparinization justified with heparin-bonded bypass circuits in cardiac surgery? Experience with and without aprotinin Transfus Apher Sci 29 2003 17 24 (Pubitemid 36870841)
21. O.M. Shapira, G.S. Aldea, J. Zelingher, J. Volpe, C. Fitzgerald, and K. DeAndrade Enhanced blood conservation and improved clinical outcome after valve surgery using heparin-bonded cardiopulmonary bypass circuits J Card Surg 11 1996 307 317 (Pubitemid 26424508)
22. A.L. Shroyer, F.L. Grover, B. Hattler, J.F. Collins, G.O. McDonald, and E. Kozora Veterans Affairs Randomized On/Off Bypass (ROOBY) Study Group. On-pump versus off-pump coronary-artery bypass surgery N Engl J Med 361 2009 1827 1837
23. R.H. Habib, A. Zachrias, and M. Engoren Determinants of prolonged mechanical ventilation after coronary artery bypass grafting Ann Thorac Surg 62 1996 1164 1171 (Pubitemid 26340341)
24. E. Øvrum, M. Abdelnoor, and K. Forfang Aortic crossclamping time and incidence of perioperative myocardial infarction after coronary artery bypass surgery Asian Cardiovasc Thorac Ann 5 1997 77 82
25. E.L. Jones, and W.S. Weintraub The importance of completeness of revascularization during long-term follow-up after coronary artery operation J Thorac Cardiovasc Surg 112 1996 227 237 (Pubitemid 26301827)