Maternal serum hCG, PAPP-A and AFP as predictors of hemoglobin Bart disease at mid-pregnancy

Prenatal Diagnosis

Volumn 31, Issue 5, 2011, Pages 430-433

  Tongprasert, Fuanglada ^a   Wanapirak, Chanane ^a   Tongsong, Theera ^a  

^a Faculty of Medicine Chiang Mai University   (Thailand)

Author keywords

human chorionic gonadotropin; Alpha fetoprotein; Fetus; Hb Bart's disease; Pregnancy associated plasma protein A

Indexed keywords

ALPHA FETOPROTEIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; HEMOGLOBIN; PREGNANCY ASSOCIATED PROTEIN;

ADULT; ALPHA THALASSEMIA; ARTICLE; CLINICAL ARTICLE; CORDOCENTESIS; DIAGNOSTIC VALUE; FEMALE; FETUS DISEASE; HEMOGLOBIN BART DISEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE BLOOD LEVEL; HUMAN; MATERNAL BLOOD; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SCREENING TEST; SECOND TRIMESTER PREGNANCY;

ADULT; ALPHA-FETOPROTEINS; CHORIONIC GONADOTROPIN; CORDOCENTESIS; FEMALE; GESTATIONAL AGE; HEMOGLOBINOPATHIES; HEMOGLOBINS, ABNORMAL; HUMANS; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY TRIMESTER, SECOND; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; PROSPECTIVE STUDIES;

EID: 79954612187     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.2705     Document Type: Article

References (16)

1. Bartha JL, Comino-Delgado R, Arce F, Alba P, Broullon JR, Barahona M. 1999. Relationship between alpha-fetoprotein and fetal erythropoiesis. J Reprod Med 44: 689-697.
2. Bartha JL, Harrison G, Kyle PM, Soothill PW. 2003. Fetal serum alpha-fetoprotein in alloimmunised pregnancies. Prenat Diagn 23: 917-920.
3. Bartha JL, Illanes S, Abdel-Fattah SA, Harrison G, Soothill PW. 2006. Maternal serum alpha-fetoprotein, fetal middle cerebral artery blood flow velocity and fetal haemoglobin in pregnancies at risk of fetal anaemia. Prenat Diagn 26: 101-104.
4. Benn PA, Egan JF, Ingardia CJ. 2002. Extreme second-trimester serum analyte values in down syndrome pregnancies with hydrops fetalis. J Matern Fetal Neonatal Med 11: 262-265.
5. Komischke K, Searle K, Enders G. 1997. Maternal serum alpha-fetoprotein and human chorionic gonadotropin in pregnant women with acute parvovirus B19 infection with and without fetal complications. Prenat Diagn 7: 1039-1046.
6. Lemmens-Zygulska M, Eigel A, Helbig B, Sanguansermsri T, Horst J, Flatz G. 1996. Prevalence of alpha-thalassemias in northern Thailand. Hum Genet 98: 345-347.
7. Manoukian AA, Bhagavan NV, Oshiro TH, Scottolini AG. 1990. Concentrations of alpha-fetoprotein increased in maternal serum but normal in amniotic fluid in a pregnancy involving hemoglobin Bart's disease. Clin Chem 36: 822.
8. Ong CY, Lee CP, Leung KY, Lau E, Tang MH. 2006. Human chorionic gonadotropin and plasma protein-A in alpha0-thalassemia pregnancies. Obstet Gynecol 108(3Pt1): 651-655.
9. Saller DN Jr, Canick JA, Oyer CE. 1996. The detection of non-immune hydrops through second-trimester maternal serum screening. Prenat Diagn 16: 431-435.
10. Saller DN Jr, Canick JA, Schwartz S, Blitzer MG. 1992. Multiple-marker screening in pregnancies with hydropic and nonhydropic Turner syndrome. Am J Obstet Gynecol 167(4Pt1): 1021-1024.
11. Spencer K, Liao AW, Skentou H, Cicero S, Nicolaides KH. 2000. Screening for triploidy by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation. Prenat Diagn 20: 495-499.
12. Srisupundit K, Piyamongkol W, Tongprasert F, Luewan S, Tongsong T. 2010. Reference range of fetal splenic circumference from 14 to 40 weeks of gestation. Arch Gynecol Obstet. [Epub ahead of print]. PMID: 20135134.
13. Tongsong T, Wanapirak C, Sirichotiyakul S. 1999a. Placental thickness at mid-pregnancy as a predictor of Hb Bart's disease. Prenat Diagn 19: 1027-1030.
14. Tongsong T, Wanapirak C, Sirichotiyakul S, Piyamongkol W, Chanprapaph P. 1999b. Fetal sonographic cardiothoracic ratio at midpregnancy as a predictor of Hb Bart disease. J Ultrasound Med 18: 807-811.
15. Tseng LH, Hwa HL, Chuang SM, Lee TY, Ko TM. 1994. Increased level of second trimester maternal serum chorionic gonadotropin in pregnancy with a fetus affected by homozygous alpha-thalassemia 1. Arch Gynecol Obstet 255: 113-117.
16. Yaron Y, Heifetz S, Ochshorn Y, Lehavi O, Orr-Urtreger A. 2002. Decreased first trimester PAPP-A is a predictor of adverse pregnancy outcome. Prenat Diagn 22: 778-782.