P-Glycoprotein (ABCB1) expression in human skin is mainly restricted to dermal components

Experimental Dermatology

Volumn 20, Issue 5, 2011, Pages 450-452

  Skazik, Claudia ^a   Wenzel, Jörg ^b   Marquardt, Yvonne ^a   Kim, Arianna ^c   Merk, Hans F ^a   Bickers, David R ^c   Baron, Jens M ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c College of Physicians and Surgeons ^*  (United States)

Author keywords

ABC transporter; Fibroblasts; Keratinocytes; P glycoprotein; Skin barrier

Indexed keywords

ABC TRANSPORTER; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1;

CONTROLLED STUDY; DERMIS; EPIDERMIS; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LETTER; NERVE SHEATH; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; SWEAT GLAND; TISSUE DISTRIBUTION;

BLOOD VESSELS; CARCINOMA, SQUAMOUS CELL; CELLS, CULTURED; DERMIS; EPIDERMIS; FIBROBLASTS; GENE EXPRESSION; HUMANS; KERATINOCYTES; LIVER; MUSCLE, SMOOTH; MYELIN SHEATH; P-GLYCOPROTEIN; SKIN; SKIN NEOPLASMS; SWEAT GLANDS;

EID: 79954607415     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2010.01237.x     Document Type: Letter

References (18)

1. Ito K, Nguyen H T, Kato Y et al. J Control Release 2008: 131: 198-204.
2. Sleeman M A, Watson J D, Murison J G. J Invest Dermatol 2000: 115: 19-23.
3. Baron J M, Holler D, Schiffer R et al. J Invest Dermatol 2001: 116: 541-548.
4. Schiffer R, Neis M, Holler D et al. J Invest Dermatol 2003: 120: 285-291.
5. Dreuw A, Hermanns H M, Heise R et al. J Invest Dermatol 2005: 124: 28-37.
6. Skazik C, Heise R, Bostanci O et al. Exp Dermatol 2008: 17: 739-747.
7. Heise R, Skazik C, Rodriguez F et al. J Invest Dermatol 2010: 130: 305-308.
8. Kruh G D, Zeng H, Rea P A et al. J Bioenerg Biomembr 2001: 33: 493-501.
9. Randolph G J, Beaulieu S, Pope M et al. Proc Natl Acad Sci USA 1998: 95: 6924-6929.
10. Borges-Walmsley M I, McKeegan Ks, Walmsley A R. Biochem J 2003: 376: 313-338.
11. Higgins C F. Nature 2007: 446: 749-757.
12. Calcabrini A, Stringaro A, Toccacieli L et al. J Invest Dermatol 2004: 122: 349-360.
13. Colone M, Calcabrini A, Toccacieli L et al. J Invest Dermatol 2008: 128: 957-971.
14. Heimerl S, Bosserhoff A K, Langmann T et al. Melanoma Res 2007: 17: 265-273.
15. Ambudkar S V, Kimchi-Sarfaty C, Sauna Z E et al. Oncogene 2003: 20: 7468-7485.
16. Calcagno A M, Kim I W, Wu C P et al. Curr Drug Deliv 2007: 4: 324-333.
17. Schmitt U, Abou El-Ela A, Guo L J et al. J Neural Transm 2006: 113: 787-801.
18. Kerstan A, Leverkus M, Trautmann A. Exp Dermatol 2009: 18: 893-899.