Development of a real-time RT-PCR assay for detection of resistance to oseltamivir in influenza A pandemic (H1N1) 2009 virus using single nucleotide polymorphism probes

Journal of Virological Methods

Volumn 173, Issue 2, 2011, Pages 259-265

  Wong, Sallene ^a   Pabbaraju, Kanti ^a   Wong, Anita ^a   Fonseca, Kevin ^a,b   Drews, Steven J ^a,b  

^a PROVINCIAL LABORATORY FOR PUBLIC HEALTH   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

H275; H275Y; Oseltamivir; Pandemic (H1N1) 2009; Real time RT PCR; Resistance; Single nucleotide polymorphism (SNP)

Indexed keywords

HISTIDINE; OSELTAMIVIR; TYROSINE; VIRUS RNA; VIRUS SIALIDASE;

2009 H1N1 INFLUENZA; ALLELE; AMINO ACID SUBSTITUTION; ANTIVIRAL RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; CONTROLLED STUDY; CROSS REACTION; GENE MUTATION; GOLD STANDARD; HUMAN; IN VITRO STUDY; INFLUENZA VIRUS A H1N1; INTERMETHOD COMPARISON; LIMIT OF DETECTION; MOLECULAR PROBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VIRUS CULTURE; WILD TYPE;

AMINO ACID SUBSTITUTION; ANTIVIRAL AGENTS; DRUG RESISTANCE, VIRAL; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; OSELTAMIVIR; POLYMORPHISM, SINGLE NUCLEOTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

INFLUENZA A VIRUS;

EID: 79954607048     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2011.02.014     Document Type: Article

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