Comparison of the new high sensitive cardiac troponin T with myoglobin, h-FABP and cTnT for early identification of myocardial necrosis in the acute coronary syndrome

Clinical Research in Cardiology

Volumn 100, Issue 3, 2011, Pages 209-215

  Kurz, Kerstin ^a   Giannitsis, Evangelos ^a   Becker, Maike ^a   Hess, Georg ^b   Zdunek, Dietmar ^b   Katus, Hugo A ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

Author keywords

Cardiac necrosis; Early detection; h FABP; High sensitive troponin T; Myoglobin

Indexed keywords

BIOLOGICAL MARKER; FATTY ACID BINDING PROTEIN; MYOGLOBIN; TROPONIN T;

ACUTE CORONARY SYNDROME; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; ASSAY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; FOLLOW UP; HEART MUSCLE NECROSIS; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PROTEIN DETERMINATION; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY ANALYSIS;

ACUTE CORONARY SYNDROME; AGED; BIOLOGICAL MARKERS; EARLY DIAGNOSIS; FATTY ACID-BINDING PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOGLOBIN; NECROSIS; TROPONIN T;

EID: 79954595952     PISSN: 18610684     EISSN: 18610692     Source Type: Journal    
DOI: 10.1007/s00392-010-0230-y     Document Type: Article

References (26)

1. K Thygesen JS Alpert HD White On behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the redefinition of Myocardial Infarction 2007 Universal definition of myocardial infarction J Am Coll Cardiol 50 2173 2195 10.1016/j.jacc.2007.09.011 18036459 (Pubitemid 350123680)
2. WT Hermens 1998 Mechanisms of protein release from injured heart muscle Dev Cardiovasc Med 205 85 98 1:CAS:528:DyaK1cXnsVWjt78%3D
3. DA Morrow CP Cannon RL Jesse LK Newby J Ravkilde AB Storrow, et al. 2007 National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes Clin Chem 53 552 574 1:CAS:528:DC%2BD2sXksFWht7c%3D 10.1373/clinchem.2006.084194 17384001 (Pubitemid 46580223)
4. T Reichlin W Hochholzer C Stelzig K Laule H Freidank NG Morgenthaler A Bergmann M Potocki M Noveanu T Breidthardt A Christ T Boldanova R Merki N Schaub R Bingisser M Christ C Mueller 2009 Incremental value of copeptin for rapid rule out of acute myocardial infarction J Am Coll Cardiol 54 60 68 1:CAS:528:DC%2BD1MXptlKltLc%3D 10.1016/j.jacc.2009.01.076 19555842
5. AH Kleine JF Glatz FA Van Nieuwenhoven GJ Van der Vusse 1992 Release of heart fatty acid-binding protein into plasma after acute myocardial infarction in man Mol Cell Biochem 116 155 162 1:STN:280:DyaK3s7isFGitQ%3D%3D 10.1007/BF01270583 1480144
6. T Reichlin W Hochholzer S Bassetti S Steuer C Stelzig S Hartwiger S Biedert N Schaub C Buerge M Potocki M Noveanu T Breidthardt R Twerenbold K Winkler R Bingisser C Mueller 2009 Early diagnosis of myocardial infarction with sensitive cardiac troponin assays N Engl J Med 361 858 867 1:CAS:528: DC%2BD1MXhtVKhtL%2FP 10.1056/NEJMoa0900428 19710484
7. E Giannitsis K Kurz K Hallermayer J Jarausch AS Jaffe HA Katus 2010 Analytical validation of a high sensitivity cardiac troponin T assay Clin Chem 56 254 261 1:CAS:528:DC%2BC3cXhslaksLc%3D 10.1373/clinchem.2009.132654 19959623
8. M Robers FF Van der Hulst MA Fischer W Roos CE Salud HG Eisenwiener, et al. 1998 Development of a rapid microparticle-enhanced turbidimetric immunoassay for plasma fatty acid-binding protein, an early marker of acute myocardial infarction Clin Chem 44 1564 1567 1:CAS:528:DyaK1cXksVSjsrY%3D 9665443 (Pubitemid 28309125)
9. E Giannitsis M Becker K Kurz G Hess D Zdunek HA Katus 2010 High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission Clin Chem 56 642 650 1:CAS:528:DC%2BC3cXksFOjsrs%3D 10.1373/clinchem.2009.134460 20167697
10. GX Brogan Jr S Friedman C McCuskey DS Cooling L Berrutti HC Thode Jr JL Bock 1994 Evaluation of a new rapid quantitative immunoassay for serum myoglobin versus CK-MB for ruling out acute myocardial infarction in the emergency department Ann Emerg Med 24 665 671 10.1016/S0196-0644(94)70276-4 8092593 (Pubitemid 24302833)
11. EM Ohman C Casey JR Bengtson D Pryor W Tormey JH Horgan 1990 Early detection of acute myocardial infarction: additional diagnostic information from serum concentrations of myoglobin in patients without ST elevation Br Heart J 63 335 338 1:STN:280:DyaK3czivFeisQ%3D%3D 10.1136/hrt.63.6.335 2375893 (Pubitemid 20182177)
12. AS Maisel K Templin M Love P Clopton 2000 A prospective study of an algorithm using cardiac troponin I and myoglobin as adjuncts in the diagnosis of acute myocardial infarction and intermediate coronary syndromes in a veteran's hospital Clin Cardiol 23 915 920 1:STN:280:DC%2BD3M7ivVOgsw%3D%3D 10.1002/clc.4960231212 11129678
13. J McCord RM Nowak PA McCullough C Foreback S Borzak G Tokarski 2001 Ninety-minute exclusion of acute myocardial infarction by use of quantitative point-of-care testing of myoglobin and troponin I Circulation 104 1483 1488 1:CAS:528:DC%2BD3MXnvVeqtb4%3D 10.1161/hc3801.096336 11571240 (Pubitemid 32917339)
14. SM Ng P Krishnaswamy R Morissey P Clopton R Fitzgerald AS Maisel 2001 Ninety-minute accelerated critical pathway for chest pain evaluation Am J Cardiol 88 611 617 1:STN:280:DC%2BD3MrhslSgtw%3D%3D 10.1016/S0002-9149(01)01801- X 11564382 (Pubitemid 32831092)
15. FS Apple CA Parvin KF Buechler RH Christenson AH Wu AS Jaffe 2005 Validation of the 99th percentile cutoff independent of assay imprecision (CV) for cardiac troponin monitoring for ruling out myocardial infarction Clin Chem 51 2198 2200 1:CAS:528:DC%2BD2MXhtFyhtL7O 10.1373/clinchem.2005.052886 16244304 (Pubitemid 41532650)
16. KM Eggers J Oldgren A Nordenskjöld B Lindahl 2004 Diagnostic value of serial measurement of cardiac markers in patients with chest pain: limited value of adding myoglobin to troponin I for exclusion of myocardial infarction Am Heart J 148 574 581 1:CAS:528:DC%2BD2cXot1Wlu78%3D 10.1016/j.ahj.2004.04.030 15459585 (Pubitemid 39349374)
17. FS Apple SW Smith LA Pearce R Ler MM Murakami 2008 Use of the Centaur TnI-Ultra assay for detection of myocardial infarction and adverse events in patients presenting with symptoms suggestive of acute coronary syndrome Clin Chem 54 723 728 1:CAS:528:DC%2BD1cXkt1equ7s%3D 10.1373/clinchem.2007.097162 18238833 (Pubitemid 351573705)
18. DC Gaze 2010 High-sensitive cardiac troponin assays: application for prime-time use Biomark Med 4 341 343 10.2217/bmm.10.18 20550467
19. G Lippi M Montagnana GC Guidi 2009 The clinical dilemma of positive results of high-sensitive troponin assays Am J Cardiol 103 1332 10.1016/j.amjcard.2009.02.037 19406287
20. M Neizel H Steen G Korosoglou D Lossnitzer S Lehrke BT Ivandic HA Katus E Giannitsis 2009 Minor troponin T elevation in patients 6 months after myocardial infarction: an observational study Clin Res Cardiol 98 297 304 1:CAS:528:DC%2BD1MXlt1Kjur0%3D 10.1007/s00392-009-0002-8 19280086
21. AHB Wu QA Lu J Todd J Moecks F Wians 2009 Short- and long-term biological variation in cardiac troponin I measured with a high-sensitivity assay: implications for clinical practice Clin Chem 55 52 58 1:CAS:528: DC%2BD1MXptFaqsw%3D%3D 10.1373/clinchem.2008.107391 18988755
22. Y Seino Y Tomita T Takano K Ohbayashi Tokyo Rapid-Test Office Cardiologists (Tokyo-ROC) Study 2004 Office cardiologists cooperative study on whole blood rapid panel tests in patients with suspicious acute myocardial infarction: comparison between heart-type fatty acid-binding protein and troponin T tests Circ J 68 144 148 10.1253/circj.68.144 14745150 (Pubitemid 38197252)
23. HA Valle LG Riesgo MS Bel FE Gonzalo MS Sanchez LI Oliva 2008 Clinical assessment of heart-type fatty acid binding protein in early diagnosis of acute coronary syndrome Eur J Emerg Med 15 140 144 10.1097/MEJ.0b013e3282efd47a 18460953 (Pubitemid 351643488)
24. F Ghani AH Wu L Graff C Petry G Armstrong F Prigent M Brown 2000 Role of heart-type fatty acid-binding protein in early detection of acute myocardial infarction Clin Chem 46 718 719 1:CAS:528:DC%2BD3cXjsVKktr8%3D 10794758 (Pubitemid 30318431)
25. T Keller T Zeller D Peetz S Tzikas A Roth E Czyz C Bickel S Baldus A Warnholtz M Fröhlich CR Sinning MS Eleftheriadis PS Wild RB Schnabel E Lubos N Jachmann S Genth-Zotz F Post V Nicaud L Tiret KJ Lackner TF Münzel S Blankenberg 2009 Sensitive troponin I assay in early diagnosis of acute myocardial infarction N Engl J Med 361 868 877 1:CAS:528:DC%2BD1MXhtVKhtLzL 10.1056/NEJMoa0903515 19710485
26. T Ilva J Lund P Porela H Mustonen LM Voipio-Pulkki S Eriksson K Pettersson P Tanner K Pulkki 2009 Early markers of myocardial injury: cTnI is enough Clin Chim Acta 400 82 85 1:CAS:528:DC%2BD1MXht1GlsQ%3D%3D 10.1016/j.cca.2008.10.005 18992232