The best algorithm to confirm the diagnosis of HTLV-1 and HTLV-2 in at-risk individuals from São Paulo, Brazil

Journal of Virological Methods

Volumn 173, Issue 2, 2011, Pages 280-286

  Costa, Emanuela A S ^a   Magri, Mariana C ^a,b   Caterino de Araujo, Adele ^a,b  

^a Secretaria de Estado da Saude de Sao Paulo   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Algorithm; Confirmatory assays; Human T cell lymphotropic virus type 1 and type 2 (HTLV 1 2); Polymerase chain reaction (PCR); Real time PCR; Western blotting (WB)

Indexed keywords

VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BRAZIL; CHILD; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DNA EXTRACTION; ENZYME IMMUNOASSAY; FEMALE; HIGH RISK PATIENT; HUMAN; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS 2; HUMAN T CELL LEUKEMIA VIRUS INFECTION; INFANT; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; VIRUS STRAIN; WESTERN BLOTTING;

HUMAN T-LYMPHOTROPIC VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 2;

EID: 79954585111     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2011.02.018     Document Type: Article

References (31)

1. Arruda B.C., Lira R.A., Loureiro P., Brandão L., Souza P., Souza W.V., Gomes Y.A. Evaluation of real time PCR technique to diagnosis of human T-lymphotropic virus type I (HTLV-I) in patients in the Hematologia da Fundação Hemope Hospital, in Northeastern Brazil. Rev. Bras. Hematol. Hemoter. 2008, 30:384-389.
2. Brasil Ministério da Saúde. Secretaria em Vigilância da Saúde. Programa Nacional de DST/AIDS. Guia de manejo clínico de HTLV. Brasília, 2003.
3. Casseb J., Souza T., Pierre-Lima M.T., Yeh E., Hendry M.R., Gallo D. Testing problems in diagnosing HTLV infection among intravenous drug users with AIDS in São Paulo city, Brazil. AIDS Res. Hum. Retroviruses 1997, 13:1639-1641.
4. Casseb J., Caterino-de-Araujo A., Hong M.A., Salomão S., Gallo D., Hendry R.M., Duarte A.J.S. Prevalence of HTLV-I and HTLV-II infections among HIV-1-infected asymptomatic individuals in São Paulo, Brazil. Rev. Inst. Med. Trop. São Paulo 1997, 39:213-215.
5. Caterino-de-Araujo A. Best screening assays for the diagnosis of human T-cell lymphotropic virus types 1 and 2 in South America. J. Virol. Methods 2009, 156:150-151.
6. Costa J.M.P., Segurado A.C. Molecular evidence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) infections in HTLV seroindeterminate individuals from São Paulo, Brazil. J. Clin. Virol. 2009, 44:185-189.
7. Costa E.A.S., Jacob F., Feliciano R., Santos-Fortuna E., Caterino-de-Araujo A. Falha na implantação de um novo algoritmo de testes laboratoriais para o diagnóstico de infecção por HTLV-1 e HTLV-2 em população de risco. Rev. Inst. Adolfo Lutz 2009, 68:314-317.
8. De-Araujo A.C., Casseb J.S.R., Neitzert E., Xavier De Souza M.L., Mammano F., Del Mistro A., De Rossi A., Chieco-Bianchi L. HTLV-I and HTLV-II infections among HIV-1 seropositive patients in São Paulo, Brazil. Eur. J. Epidemiol. 1994, 1:165-171.
9. Estes M.C., Sevall J.S. Multiplex PCR using real time DNA amplification for the rapid detection and quantitation of HTLV I or II. Mol. Cell. Probes 2003, 17:59-68.
10. Gasperini P., Barbierato M., Martinelli C., Rigotti P., Marchini F., Masserizzi G., Leoncini F., Chieco-Bianchi L., Schulz T.F., Calabrò M.L. Use of a BJAB-derivated cell line for isolation of human herpesvirus 8. J. Clin. Microbiol. 2005, 43:2866-2875.
11. Heneine W., Khabbaz R.F., Lal R.B., Kaplan J.E. Sensitive and specific polymerase chain reaction assays for diagnosis of human T-cell lymphotropic virus type I (HTLV-I) and HTLV-II infections in HTLV-I/II seropositive individuals. J. Clin. Microbiol. 1992, 30:1605-1607.
12. Ishak R., Vallinotto A.C.R., Azevedo V.N., Vicente A.C.P., Hall W.W., Ishak M.O.G. Molecular evidence for infection by HTLV-2 among individuals with negative serological screening tests for HTLV antibodies. Epidemiol. Infect. 2007, 135:604-609.
13. Jacob F., Santos-Fortuna E., Azevedo R.S., Caterino-de-Araujo A. Performances of HTLV serological tests in diagnosing HTLV infection in high-risk population of São Paulo, Brazil. Rev. Inst. Med. Trop. São Paulo 2007, 49:361-364.
14. Jacob F., Santos-Fortuna E., Azevedo R.S., Caterino-de-Araujo A. Serological patterns and temporal trends of HTLV-1/2 infection in high-risk populations attending public health units in São Paulo, Brazil. J. Clin. Virol. 2008, 42:149-155.
15. Jacob F., Magri M.C., Costa E.A.S., Santos-Fortuna E., Caterino-de Araujo A. Comparison of signal-to-cutoff values in first, second, and third generation enzyme immunoassays for the diagnosis of HTLV-1/2 infection in "at-risk" individuals from São Paulo, Brazil. J. Virol. Methods 2009, 159:288-290.
16. Laurentino R.V., Lopes I.G.L., Azevedo V.N., Machado L.F., Moreira M.R., Lobato L., Ishak M.O.G., Ishak R., Vallinoto A.C.R. Molecular characterization of human T-cell lymphotropic virus coinfecting human immunodeficiency virus 1 infected patients in the Amazon region of Brazil. Mem. Inst. Oswaldo Cruz 2005, 100:371-376.
17. Lee T.H., Chafets D.M., Busch M.P., Murphy E.L. Quantitation of HTLV-I and II proviral load using real-time quantitative PCR with SYBR green chemistry. J. Clin. Virol. 2004, 31:275-282.
18. Machuca A., Soriano V. In vivo fluctuation of HTLV-I and HTLV-II proviral load in patients receiving antiretroviral drugs. J. Acquir. Immune Defic. Syndr. 2000, 24:189-193.
19. Montanheiro P.A., Oliveira A.C., Posada-Vergara M.P., Milagres A.C., Tauil C., Marchiori P.E., Duarte A.J.S., Casseb J. Human T-cell lymphotropic virus type I (HTLV-I) proviral DNA viral load among asymptomatic patients and patients with HTLV-II-associated myelopathy/tropical spastic paraparesis. Braz. J. Med. Biol. Res. 2005, 28:1643-1647.
20. Montanheiro P.A., Olah I., Fukumori L.M.I., Smid J., Penalva de Oliveira A.C., Kanzaki L.I.B., Fonseca L.A.M., Duarte A.J.S., Casseb J. Low DNA HTLV-2 proviral load among women in São Paulo city. Virus Res. 2008, 135:22-25.
21. Morimoto H.K., Morimoto A.A., Reiche E.M.V., Ueda L.T., Matsuo T., Reiche F.V., Caterino-de-Araujo A. Difficulties in the diagnosis of HTLV-2 infection in HIV/AIDS patients from Brazil: comparative performances of serologic and molecular assays, and detection of HTLV-2b subtype. Rev. Inst. Med. Trop. São Paulo 2007, 49:225-230.
22. Murphy E.L., Lee T.-H., Chafets D., Nass C.C., Wang B., Loughlin K., Smith D. Higher human T lymphotropic virus (HTLV) provirus load is associated with HTLV-I versus HTLV-II, with HTLV-II subtype A versus B, and with male sex and history of blood transfusion. J. Infect. Dis. 2004, 190:504-510. for the HTLV outcomes study investigators.
23. Novoa P., Penalva de Oliveira A.C., Posada-Vergara M.P., Duarte A.J.S., Casseb J. Molecular characterization of human T-cell lymphotropic virus type 2 (HTLV-II) from people living in urban areas of São Paulo city: evidence of multiple subtypes circulation. J. Med. Virol. 2007, 79:182-187.
24. Popovic M., Sarin P.S., Robert-Gurroff M., Kalyanaraman V.S., Mann D., Minowada J., Gallo R.C. Isolation and transmission of human retrovirus (human T-cell leukemia virus). Science 1983, 219:856-859.
25. Proietti F.A., Carneiro-Proietti A.B.F., Catalan-Soares B.C., Murphy E.L. Global epidemiology of HTLV-I infection and associated diseases. Oncogene 2005, 24:6058-6068.
26. Segurado A.A.C., Malaque C.M.S., Sumita L.M., Pannuti C.S., Lal R.B. Laboratory characterization of human T cell lymphotropic virus types 1 (HTLV-1) and 2 (HTLV-2) infections in blood donors from São Paulo, Brazil. Am. J. Trop. Med. Hyg. 1997, 57:142-148.
27. Segurado A.C.C., Biasutti C., Zeigler R., Rodrigues C., Damas C.D., Jorge M.L.S.G., Marchiori P.E. Identification of human T-lymphotropic virus type I (HTLV-I) subtypes using restricted fragment length polymorphism in a cohort of asymptomatic carriers and patients with HTLV-I associated myelopathy/tropical spastic paraparesis from São Paulo, Brazil. Mem. Inst. Oswaldo Cruz 2002, 97:329-333.
28. Souza L.A., Lopes I.G.L., Maia E.L., Azevedo V.N., Machado L.F.A., Ishak M.O.G., Ishak R., Vallinoto A.C.R. Caracterização molecular do HTLV-1 em pacientes com paraparesia espástica tropical/mielopatia associada ao HTLV-1 em Belém, Pará. Rev. Soc. Bras. Med. Trop. 2006, 39:504-506.
29. Tamegão-Lopes B.P., Rezende P.R., Maradei-Pereira L.M.C., Lemos J.A.R. HTLV-1 and HTLV-2 proviral load: a simple method using quantitative real-time PCR. Rev. Soc. Bras. Med. Trop. São Paulo 2006, 39:548-552.
30. Tuke P.W., Luton P., Garson J.A. Differential diagnosis of HTLV-I and HTLV-II infections by restriction enzyme analysis of "nested" PCR products. J. Virol. Methods 1992, 40:163-174.
31. Vallinoto A.C.R., Pontes G.S., Muto N.A., Lopes I.G., Machado L.F., Azevedo Z.N., Carvalhaes F.A.P.L., Santos S.E.B., Guerreiro J.F., Ishak M.O.G., Ishak R. Identification of human T-cell lymphotropic virus infection in a semi-isolated afro-brazilian quilombo located in the Marajó island (Pará Brazil). Mem. Inst. Oswaldo Cruz 2006, 101:103-105.