Suppression of experimental abdominal aortic aneurysm in a rat model by the phosphodiesterase 3 inhibitor cilostazol

Journal of Surgical Research

Volumn 167, Issue 2, 2011, Pages

  Zhang, Qi ^a   Huang, Jian Hua ^a   Xia, Ren Peng ^a   Duan, Xiao Hui ^a   Jiang, Yi Bo ^a   Jiang, Qin ^a   Sun, Wei Jia ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

abdominal aortic aneurysm; cilostazol; elastin; metalloproteinase; NADPH oxidase; nuclear factor B; oxidative stress; reactive oxygen species; vascular inflammation

Indexed keywords

CILOSTAZOL; ELASTIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHODIESTERASE III; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD PRESSURE; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING;

ANIMALS; AORTIC ANEURYSM, ABDOMINAL; BLOOD PRESSURE; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MODELS, ANIMAL; NADPH OXIDASE; NF-KAPPA B; PANCREATIC ELASTASE; PHOSPHODIESTERASE 3 INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; TETRAZOLES;

EID: 79954571021     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.01.017     Document Type: Article

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