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Volumn 3, Issue 1, 2011, Pages 38-47

Expression of neurogenesis genes in human temporal lobe epilepsy with hippocampal sclerosis

Author keywords

Bromodeoxyuridine; Epileptogenesis; Mesial temporal sclerosis; Neurogenesis; Seizure

Indexed keywords

COLLAPSIN RESPONSE MEDIATOR PROTEIN; DOUBLECORTIN; NEUROGENIC DIFFERENTIATION FACTOR; NEURON SPECIFIC NUCLEAR PROTEIN;

EID: 79954554208     PISSN: None     EISSN: 19448171     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (59)
  • 2
    • 0033569665 scopus 로고    scopus 로고
    • Neurogenesis in the neocortex of adult primates
    • Gould E, Reeves AJ, Graziano MS and Gross CG. Neurogenesis in the neocortex of adult primates. Science 1999; 286: 548-552.
    • (1999) Science , vol.286 , pp. 548-552
    • Gould, E.1    Reeves, A.J.2    Graziano, M.S.3    Gross, C.G.4
  • 3
    • 23244458855 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian central nervous system
    • Ming GL and Song H. Adult neurogenesis in the mammalian central nervous system. Annu Rev Neurosci 2005; 28: 223-250.
    • (2005) Annu Rev Neurosci , vol.28 , pp. 223-250
    • Ming, G.L.1    Song, H.2
  • 4
    • 33644507720 scopus 로고    scopus 로고
    • Adult neurogenesis and functional plasticity in neuronal circuits
    • Lledo PM, Alonso M and Grubb MS. Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci 2006; 7: 179-193.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 179-193
    • Lledo, P.M.1    Alonso, M.2    Grubb, M.S.3
  • 5
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
    • Kuhn HG, Dickinson-Anson H and Gage FH. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 1996; 16: 2027-2033.
    • (1996) J Neurosci , vol.16 , pp. 2027-2033
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 7
    • 65549125564 scopus 로고    scopus 로고
    • Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain
    • Ahlenius H, Visan V, Kokaia M, Lindvall O and Kokaia Z. Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain. J Neurosci 2009; 29: 4408-4419.
    • (2009) J Neurosci , vol.29 , pp. 4408-4419
    • Ahlenius, H.1    Visan, V.2    Kokaia, M.3    Lindvall, O.4    Kokaia, Z.5
  • 9
    • 0035868717 scopus 로고    scopus 로고
    • Neurogenesis in the adult is involved in the formation of trace memories
    • Shors TJ, Miesegaes G, Beylin A, Zhao M, Rydel T and Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature 2001; 410: 372-376.
    • (2001) Nature , vol.410 , pp. 372-376
    • Shors, T.J.1    Miesegaes, G.2    Beylin, A.3    Zhao, M.4    Rydel, T.5    Gould, E.6
  • 13
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson A, Collin T, Kirik D, Kokaia Z and Lindvall O. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002; 8: 963-970.
    • (2002) Nat Med , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 14
    • 28044445105 scopus 로고    scopus 로고
    • Reappearance of hippocampal CA1 neurons after ischemia is associated with recovery of learning and memory
    • Bendel O, Bueters T, von Euler M, Ove Ogren S, Sandin J and von Euler G. Reappearance of hippocampal CA1 neurons after ischemia is associated with recovery of learning and memory. J Cereb Blood Flow Metab 2005; 25: 1586-1595.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1586-1595
    • Bendel, O.1    Bueters, T.2    von Euler, M.3    Ove, O.S.4    Sandin, J.5    von Euler, G.6
  • 15
    • 44349104927 scopus 로고    scopus 로고
    • Proliferating progenitor cells: A required cellular element for induction of ischemic tolerance in the brain
    • Maysami S, Lan JQ, Minami M and Simon RP. Proliferating progenitor cells: a required cellular element for induction of ischemic tolerance in the brain. J Cereb Blood Flow Metab 2008; 28: 1104-1113.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 1104-1113
    • Maysami, S.1    Lan, J.Q.2    Minami, M.3    Simon, R.P.4
  • 16
    • 0030612186 scopus 로고    scopus 로고
    • Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures
    • Bengzon J, Kokaia Z, Elmer E, Nanobashvili A, Kokaia M and Lindvall O. Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures. Proc Natl Acad Sci USA 1997; 94: 10432-10437.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10432-10437
    • Bengzon, J.1    Kokaia, Z.2    Elmer, E.3    Nanobashvili, A.4    Kokaia, M.5    Lindvall, O.6
  • 17
    • 0030907041 scopus 로고    scopus 로고
    • Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus
    • Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS and Lowenstein DH. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci 1997; 17: 3727-3738.
    • (1997) J Neurosci , vol.17 , pp. 3727-3738
    • Parent, J.M.1    Yu, T.W.2    Leibowitz, R.T.3    Geschwind, D.H.4    Sloviter, R.S.5    Lowenstein, D.H.6
  • 18
    • 0034663012 scopus 로고    scopus 로고
    • Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: Functional implications of seizure-induced neurogenesis
    • Scharfman HE, Goodman JH and Sollas AL. Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis. J Neurosci 2000; 20: 6144-6158.
    • (2000) J Neurosci , vol.20 , pp. 6144-6158
    • Scharfman, H.E.1    Goodman, J.H.2    Sollas, A.L.3
  • 19
    • 0038169897 scopus 로고    scopus 로고
    • Dentate granule cell neurogenesis after seizures induced by pentylenetrazol in rats
    • Jiang W, Wan Q, Zhang ZJ, Wang WD, Huang YG, Rao ZR and Zhang X. Dentate granule cell neurogenesis after seizures induced by pentylenetrazol in rats. Brain Res 2003; 977: 141-148.
    • (2003) Brain Res , vol.977 , pp. 141-148
    • Jiang, W.1    Wan, Q.2    Zhang, Z.J.3    Wang, W.D.4    Huang, Y.G.5    Rao, Z.R.6    Zhang, X.7
  • 20
    • 34548413314 scopus 로고    scopus 로고
    • Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling
    • Jessberger S, Zhao C, Toni N, Clemenson GD, Jr., Li Y and Gage FH. Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling. J Neurosci 2007; 27: 9400-9407.
    • (2007) J Neurosci , vol.27 , pp. 9400-9407
    • Jessberger, S.1    Zhao, C.2    Toni, N.3    Clemenson Jr., G.D.4    Li, Y.5    Gage, F.H.6
  • 21
    • 0035783732 scopus 로고    scopus 로고
    • Caspase inhibitors increase short-term survival of progenitor-cell progeny in the adult rat dentate gyrus following status epilepticus
    • Ekdahl CT, Mohapel P, Elmer E and Lindvall O. Caspase inhibitors increase short-term survival of progenitor-cell progeny in the adult rat dentate gyrus following status epilepticus. Eur J Neurosci 2001; 14: 937-945.
    • (2001) Eur J Neurosci , vol.14 , pp. 937-945
    • Ekdahl, C.T.1    Mohapel, P.2    Elmer, E.3    Lindvall, O.4
  • 22
    • 0036458737 scopus 로고    scopus 로고
    • Seizure-induced neurogenesis: Are more new neurons good for an adult brain?
    • Parent JM and Lowenstein DH. Seizure-induced neurogenesis: are more new neurons good for an adult brain? Prog Brain Res 2002; 135: 121-131.
    • (2002) Prog Brain Res , vol.135 , pp. 121-131
    • Parent, J.M.1    Lowenstein, D.H.2
  • 23
    • 33846586998 scopus 로고    scopus 로고
    • Neuroscience. Is more neurogenesis always better?
    • Scharfman HE and Hen R. Neuroscience. Is more neurogenesis always better? Science 2007; 315: 336-338.
    • (2007) Science , vol.315 , pp. 336-338
    • Scharfman, H.E.1    Hen, R.2
  • 24
    • 3242687976 scopus 로고    scopus 로고
    • Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis
    • Cha BH, Akman C, Silveira DC, Liu X and Holmes GL. Spontaneous recurrent seizure following status epilepticus enhances dentate gyrus neurogenesis. Brain Dev 2004; 26: 394-397.
    • (2004) Brain Dev , vol.26 , pp. 394-397
    • Cha, B.H.1    Akman, C.2    Silveira, D.C.3    Liu, X.4    Holmes, G.L.5
  • 25
    • 9644289380 scopus 로고    scopus 로고
    • Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus
    • Hattiangady B, Rao MS and Shetty AK. Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus. Neurobiol Dis 2004; 17: 473-490.
    • (2004) Neurobiol Dis , vol.17 , pp. 473-490
    • Hattiangady, B.1    Rao, M.S.2    Shetty, A.K.3
  • 26
    • 27644485844 scopus 로고    scopus 로고
    • Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures
    • Kralic JE, Ledergerber DA and Fritschy JM. Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures. Eur J Neurosci 2005; 22: 1916-1927.
    • (2005) Eur J Neurosci , vol.22 , pp. 1916-1927
    • Kralic, J.E.1    Ledergerber, D.A.2    Fritschy, J.M.3
  • 27
    • 33745191020 scopus 로고    scopus 로고
    • Impairment of dentate gyrus neuronal progenitor cell differentiation in a mouse model of temporal lobe epilepsy
    • Ledergerber D, Fritschy JM and Kralic JE. Impairment of dentate gyrus neuronal progenitor cell differentiation in a mouse model of temporal lobe epilepsy. Exp Neurol 2006; 199: 130-142.
    • (2006) Exp Neurol , vol.199 , pp. 130-142
    • Ledergerber, D.1    Fritschy, J.M.2    Kralic, J.E.3
  • 29
    • 0031792967 scopus 로고    scopus 로고
    • Remodeling of neuronal circuitries in human temporal lobe epilepsy: Increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex
    • Mikkonen M, Soininen H, Kalvianen R, Tapiola T, Ylinen A, Vapalahti M, Paljarvi L and Pitkanen A. Remodeling of neuronal circuitries in human temporal lobe epilepsy: increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex. Ann Neurol 1998; 44: 923-934.
    • (1998) Ann Neurol , vol.44 , pp. 923-934
    • Mikkonen, M.1    Soininen, H.2    Kalvianen, R.3    Tapiola, T.4    Ylinen, A.5    Vapalahti, M.6    Paljarvi, L.7    Pitkanen, A.8
  • 32
    • 0034940120 scopus 로고    scopus 로고
    • Increase of nestin-immunoreactive neural precursor cells in the dentate gyrus of pediatric patients with early-onset temporal lobe epilepsy
    • Blumcke I, Schewe JC, Normann S, Brustle O, Schramm J, Elger CE and Wiestler OD. Increase of nestin-immunoreactive neural precursor cells in the dentate gyrus of pediatric patients with early-onset temporal lobe epilepsy. Hippocampus 2001; 11: 311-321.
    • (2001) Hippocampus , vol.11 , pp. 311-321
    • Blumcke, I.1    Schewe, J.C.2    Normann, S.3    Brustle, O.4    Schramm, J.5    Elger, C.E.6    Wiestler, O.D.7
  • 33
    • 0036334009 scopus 로고    scopus 로고
    • Seizures decrease postnatal neurogenesis and granule cell development in the human fascia dentata
    • Mathern GW, Leiphart JL, De Vera A, Adelson PD, Seki T, Neder L and Leite JP. Seizures decrease postnatal neurogenesis and granule cell development in the human fascia dentata. Epilepsia 2002; 43 Suppl 5: 68-73.
    • (2002) Epilepsia , vol.43 , Issue.SUPPL. 5 , pp. 68-73
    • Mathern, G.W.1    Leiphart, J.L.2    de Vera, A.3    Adelson, P.D.4    Seki, T.5    Neder, L.6    Leite, J.P.7
  • 34
    • 36248930499 scopus 로고    scopus 로고
    • Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy
    • Engel T, Murphy BM, Schindler CK and Henshall DC. Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy. Epilepsy Res 2007; 77: 151-156.
    • (2007) Epilepsy Res , vol.77 , pp. 151-156
    • Engel, T.1    Murphy, B.M.2    Schindler, C.K.3    Henshall, D.C.4
  • 37
    • 0026697724 scopus 로고
    • NeuN, a neuronal specific nuclear protein in vertebrates
    • Mullen RJ, Buck CR and Smith AM. NeuN, a neuronal specific nuclear protein in vertebrates. Development 1992; 116: 201-211.
    • (1992) Development , vol.116 , pp. 201-211
    • Mullen, R.J.1    Buck, C.R.2    Smith, A.M.3
  • 38
    • 0030597343 scopus 로고    scopus 로고
    • A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution
    • Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M and Nonaka M. A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution. Gene 1996; 180: 157-163.
    • (1996) Gene , vol.180 , pp. 157-163
    • Hamajima, N.1    Matsuda, K.2    Sakata, S.3    Tamaki, N.4    Sasaki, M.5    Nonaka, M.6
  • 39
    • 0032849683 scopus 로고    scopus 로고
    • A family of proteins implicated in axon guidance and outgrowth
    • Quinn CC, Gray GE and Hockfield S. A family of proteins implicated in axon guidance and outgrowth. J Neurobiol 1999; 41: 158-164.
    • (1999) J Neurobiol , vol.41 , pp. 158-164
    • Quinn, C.C.1    Gray, G.E.2    Hockfield, S.3
  • 41
    • 0033152450 scopus 로고    scopus 로고
    • Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
    • Gleeson JG, Lin PT, Flanagan LA and Walsh CA. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 1999; 23: 257-271.
    • (1999) Neuron , vol.23 , pp. 257-271
    • Gleeson, J.G.1    Lin, P.T.2    Flanagan, L.A.3    Walsh, C.A.4
  • 42
    • 0029068316 scopus 로고
    • Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
    • Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N and Weintraub H. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 1995; 268: 836-844.
    • (1995) Science , vol.268 , pp. 836-844
    • Lee, J.E.1    Hollenberg, S.M.2    Snider, L.3    Turner, D.L.4    Lipnick, N.5    Weintraub, H.6
  • 44
    • 0033165994 scopus 로고    scopus 로고
    • NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus
    • Miyata T, Maeda T and Lee JE. NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus. Genes Dev 1999; 13: 1647-1652.
    • (1999) Genes Dev , vol.13 , pp. 1647-1652
    • Miyata, T.1    Maeda, T.2    Lee, J.E.3
  • 45
    • 0346732391 scopus 로고    scopus 로고
    • Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis
    • Li HS, Wang D, Shen Q, Schonemann MD, Gorski JA, Jones KR, Temple S, Jan LY and Jan YN. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron 2003; 40: 1105-1118.
    • (2003) Neuron , vol.40 , pp. 1105-1118
    • Li, H.S.1    Wang, D.2    Shen, Q.3    Schonemann, M.D.4    Gorski, J.A.5    Jones, K.R.6    Temple, S.7    Jan, L.Y.8    Jan, Y.N.9
  • 46
    • 3342938070 scopus 로고    scopus 로고
    • Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
    • Petersen PH, Zou K, Krauss S and Zhong W. Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci 2004; 7: 803-811.
    • (2004) Nat Neurosci , vol.7 , pp. 803-811
    • Petersen, P.H.1    Zou, K.2    Krauss, S.3    Zhong, W.4
  • 47
    • 34347356438 scopus 로고    scopus 로고
    • Numb, neurogenesis and epithelial polarity
    • Kim S and Walsh CA. Numb, neurogenesis and epithelial polarity. Nat Neurosci 2007; 10: 812-813.
    • (2007) Nat Neurosci , vol.10 , pp. 812-813
    • Kim, S.1    Walsh, C.A.2
  • 48
    • 0000738525 scopus 로고    scopus 로고
    • Hippocampal Sclerosis
    • In: Engel JJ, Pedley TA, editors, Philadelphia: Lippincott-Raven Publishers
    • Mathern GW, Babb TL and Armstrong DL. Hippocampal Sclerosis. In: Engel JJ, Pedley TA, editors. Epilepsy: a comprehensive textbook. Philadelphia: Lippincott-Raven Publishers; 1997. p. 133-155.
    • (1997) Epilepsy: A comprehensive textbook , pp. 133-155
    • Mathern, G.W.1    Babb, T.L.2    Armstrong, D.L.3
  • 49
    • 69949142062 scopus 로고    scopus 로고
    • Hippocampal sclerosis: Progress since Sommer
    • Thom M. Hippocampal sclerosis: progress since Sommer. Brain Pathol 2009; 19: 565-572.
    • (2009) Brain Pathol , vol.19 , pp. 565-572
    • Thom, M.1
  • 50
    • 35748953722 scopus 로고    scopus 로고
    • Is neurogenesis reparative after status epilepticus?
    • Parent JM, Jessberger S, Gage FH and Gong C. Is neurogenesis reparative after status epilepticus? Epilepsia 2007; 48 Suppl 8: 69-71.
    • (2007) Epilepsia , vol.48 , Issue.SUPPL. 8 , pp. 69-71
    • Parent, J.M.1    Jessberger, S.2    Gage, F.H.3    Gong, C.4
  • 51
    • 0028885024 scopus 로고
    • TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth
    • Minturn JE, Fryer HJ, Geschwind DH and Hockfield S. TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth. J Neurosci 1995; 15: 6757-6766.
    • (1995) J Neurosci , vol.15 , pp. 6757-6766
    • Minturn, J.E.1    Fryer, H.J.2    Geschwind, D.H.3    Hockfield, S.4
  • 52
    • 70949092754 scopus 로고    scopus 로고
    • Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors
    • Kim KK, Adelstein RS and Kawamoto S. Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J Biol Chem 2009; 284: 31052-31061.
    • (2009) J Biol Chem , vol.284 , pp. 31052-31061
    • Kim, K.K.1    Adelstein, R.S.2    Kawamoto, S.3
  • 53
    • 0036428732 scopus 로고    scopus 로고
    • Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus
    • Ekdahl CT, Mohapel P, Weber E, Bahr B, Blomgren K and Lindvall O. Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus. Eur J Neurosci 2002; 16: 1463-1471.
    • (2002) Eur J Neurosci , vol.16 , pp. 1463-1471
    • Ekdahl, C.T.1    Mohapel, P.2    Weber, E.3    Bahr, B.4    Blomgren, K.5    Lindvall, O.6
  • 56
    • 76749107731 scopus 로고    scopus 로고
    • Apoptosis, Bcl-2 family proteins and caspases: The ABCs of seizuredamage and epileptogenesis?
    • Engel T and Henshall DC. Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizuredamage and epileptogenesis? Int J Physiol Pathophysiol Pharmacol 2009; 1: 97-115.
    • (2009) Int J Physiol Pathophysiol Pharmacol , vol.1 , pp. 97-115
    • Engel, T.1    Henshall, D.C.2
  • 57
    • 0037183723 scopus 로고    scopus 로고
    • Seizure induced dentate neurogenesis does not diminish with age in rats
    • Gray WP, May K and Sundstrom LE. Seizure induced dentate neurogenesis does not diminish with age in rats. Neurosci Lett 2002; 330: 235-238.
    • (2002) Neurosci Lett , vol.330 , pp. 235-238
    • Gray, W.P.1    May, K.2    Sundstrom, L.E.3
  • 58
    • 0036456829 scopus 로고    scopus 로고
    • Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited
    • Mathern GW, Adelson PD, Cahan LD and Leite JP. Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. Prog Brain Res 2002; 135: 237-251.
    • (2002) Prog Brain Res , vol.135 , pp. 237-251
    • Mathern, G.W.1    Adelson, P.D.2    Cahan, L.D.3    Leite, J.P.4
  • 59
    • 0037218819 scopus 로고    scopus 로고
    • Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
    • Lai K, Kaspar BK, Gage FH and Schaffer DV. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat Neurosci 2003; 6: 21-27.
    • (2003) Nat Neurosci , vol.6 , pp. 21-27
    • Lai, K.1    Kaspar, B.K.2    Gage, F.H.3    Schaffer, D.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.