Editorial

Anti-Cancer Agents in Medicinal Chemistry

Volumn 11, Issue 3, 2011, Pages 247-248

  Hassan, Hassan T ^a  

^a UNIVERSITY OF THE WEST OF SCOTLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AJOENE; AJOENE DERIVATIVE; ALLICIN; ALLYL SULFIDE; ANTINEOPLASTIC AGENT; CYTARABINE; DIALLYL DISULFIDE; DIALLYL TRISULFIDE; DIALLYLMETHYLDIISULFIDE; DIALLYLMETHYLTRISULFIDE; FLUDARABINE; GARLIC EXTRACT; HISTONE DEACETYLASE; ORGANOSULFUR DERIVATIVE; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE; PLANT EXTRACT; SULFUR DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; BASAL CELL CARCINOMA; CANCER CELL CULTURE; CANCER RESISTANCE; CANCER RISK; CANCER SURVIVAL; CELL PROLIFERATION; DRUG EFFICACY; DRUG MECHANISM; EDITORIAL; ENZYME INHIBITION; FOOD INTAKE; GARLIC; HUMAN; METASTASIS; MULTIDRUG RESISTANCE; PROSTATE CANCER; PROSTATE HYPERTROPHY; RISK REDUCTION; TREATMENT RESPONSE; CHEMISTRY; CLINICAL TRIAL (TOPIC); NEOPLASM;

ALLIUM; ANTINEOPLASTIC AGENTS; CLINICAL TRIALS AS TOPIC; HUMANS; NEOPLASMS; PLANT EXTRACTS; SULFUR COMPOUNDS;

EID: 79954551653     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (16)

1. Weisberger, A. S; Pensky, J. Tumour inhibition ba a sulfhydryl-blocking agent related to active principle of garlic (Allium Sativum). Cancer Res., 1958, 18, 1301-1308.
2. Jiroveta, L.; Jäger, W.; Koch, H.P.; Remberg, G. Investigation of the volatile constituents of the essential oil of Egyptian garlic (Allium sativum) by means of GC-MS and GC-FTIR. Z Lebensm-Unters Forschung, 1992, 194, 363-365.
3. Rosen, R.T.; Hiserodt, R.D.; Fukuda, E.K.; Ruiz, R.J.; Zhou, Z.; Lach, J.; Rosen, S.L.; Hartman, T.G. Determination of allicin, s-allylcysteiene and volatile metabolites of garlic in breath, plasma or stimulated gastric fluids. J. Nutr., 2001, 131, 968S-971S.
4. Minami, T; Boku, T.; Inada, K.; Morita, M.; Okazaki, Y. Odor componentsof human breath after the ingestion of grated raw garlic. J. Food Sci., 1989, 54, 763-765.
5. Egen-Schwind, C.; Eckard, R.; Kemper, F.H. Metabolism of garlic constituents in the isolated perfused rat liver. Planta Med., 1992, 58, 301-305.
6. Steinmetz, K.A.; Kushi, L.H.; Bostick, R.M.; Folsom, A.R.; Potter, J.D. Vegetables, fruits and colon cancer in the Iowa women's health study. Am. J. Epidemol., 1994, 139, 1-15.
7. Buiatti, D.; Palli, A.; Decardi, D.; Amadori, C.; Avellini, S.; Bianchi, R.; Biserni, F.; Cipriani, P.; Cocoo, A.; Giacosa, A. Case control study of gastric cancer and diet cin Italy. Int. J. Cancer, 1989, 44, 611-616.
8. Gao, C.M., Takezaki, J.H.; Ding, M.S.; Li, K.; Tajima, K. Protective effect of Allium vegetables against both oesophageal and stomach cancer: a simultaneous case reference study of a high epidemic area in Jiangsu providence, China. Jpn. J. Cancer Res., 1999, 90, 610-614.
9. Key, T.J.A.; Silcocks, P.B.; Davey, G.K.; Appleby, P.N.; Bishop, D.T. A case-control study of diet and prostate cancer. Br. J. Cancer, 1997, 76, 678-687.
10. Galeone, C., Pelucchi, C., Levi, F.; Negri, E. Onion and garlic use and human cancer. Am. J. Clin. Nutr., 2006, 84, 1027-1032.
11. Zheng, W; Blot, W.J.; Shu, X.O.; Gao, Y.T.; Ji, B.T.; Ziegler, R.G.; Fraumeni, J.F. Jr. Diet and other risk factors for laryngeal cancer in Shanghai, China. Am. J. Epidemiol., 1992, 136, 178-191.
12. Hassan, H.T. Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy. Leuk Res., 2004, 28, 667-671.
13. Ahmed, N; Laverick, L.; Sammons, J.; Zhang, H.; Maslin, D.; Hassan, H.T. Ajoene, a garlic-derived natural compound, emhances chemotherapyinduced apoptosis in human myeloid leukaemia CD34 positive resistant cells. Anticancer Res., 2001, 21, 3519-3525.
14. Arora, A.; Seth, K.; Shukla, Y. Reversal of p-glycoprotein-mediated multidrug resistance by diallyl sulphide in K562 leukemia cells and in mouse liver. Carcinogenesis, 2004, 25, 941-949.
15. Tilli, C.M.L.J.; Stavast-Kooy, A.J.W.; Vuerstack, J.D.D.; Thissen, M.R.T.M.; Krekels, G.A.M.; Ramackers, F.C.S.; Neumann, H.A.M. The garlicderived organosulfur component ajoene decreases basal cell carcinoma tumour size by inducing apoptosis. Arch. Dermatol. Res., 2003, 205, 117-123.
16. Durak, I.; Yilmaz, E.; Devrim, E.; Perk, H.; Kacmaz, M. Consumption of garlic extract leads to sifnigicant improvements in patients with benign prostate hyperplasia and prostate cancer. Nutr. Res., 2003, 23, 199-204.